Abstract: A system comprising a multi-sensor catheter for monitoring of a cardiac hemodynamic condition, e.g. heart failure, is disclosed. The multi-sensor catheter comprises multi-lumen catheter tubing comprising first and second optical pressure sensors, and their respective optical fibers and connectors. For right heart and pulmonary artery catheterization, a flow-directed multi-sensor catheter comprises a guidewire lumen, an inflatable balloon tip, and sensor locations are configured for placement of a sensor in each of the right atrium and pulmonary artery, for measurement of central venous pressure in the right atrium and a pulmonary artery pressure. An optical fiber for oximetry may be included. The outside diameter is small enough for insertion through a vein of the arm. For monitoring of a left atrial shunt, sensors of a multi-sensor catheter are configured for measuring pressures upstream and downstream of the shunt, e.g. in the left and right atria, or left atrium and coronary sinus.
Type:
Grant
Filed:
September 30, 2019
Date of Patent:
March 15, 2022
Assignee:
HemoCath Ltd.
Inventors:
Christopher Glover, Eric Caron, Sylvain Abel
Abstract: A system (1) and apparatus comprising a multisensor guidewire (100/200/300) for use in interventional cardiology, e.g., Transcatheter Valve Therapies (TVT), comprises a plurality of optical sensors (10/20) for direct measurement of cardiovascular parameters, e.g. transvalvular blood pressure gradients and flow. A conventional outer coil wire (35) contains a shaped core wire (31) having a cross-section defining a channel surface (132), e.g. grooves (32), extending along its length, to position optical fibers (11) and optical sensors (10/20) in a channel (33). Advantageously, the core wire has a diameter that provides sufficient stiffness to the guidewire for use as a support guidewire for TVT, e.g. Transcatheter Aortic Valve Implantation (TAVI), while accommodating multiple sensors and fibers within a guidewire of outside diameter ?0.89 mm. An optical connector (112) couples the guidewire to a control system (150).