Abstract: There are provided biocompatible chemical compositions having oxygen transporting capability and comprising oxygen transporting molecules chemically bound to antioxidants, to form compositions capable of protecting a mammalian body from oxidative damage. An example of a composition according to the invention is hemoglobin covalently coupled to a 6-hydroxy chroman carboxylic acid, such as Trolox.
Type:
Grant
Filed:
March 20, 2000
Date of Patent:
December 13, 2005
Assignee:
Hemosol LP
Inventors:
James Gordon Adamson, Greg Angus McIntosh