Patents Assigned to HEMOTEQ AG
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Publication number: 20240082463Abstract: The present invention relates to a suspension for coating of medical devices containing at least one tri-O-acylglycerol, at least one taxane in the form of microcrystals and at least one solvent in which the at least one tri-O-acylglycerol dissolves and in which the microcrystals of the at least one taxane do not dissolve. Furthermore, the present invention relates to a p method for preparing said suspension, a p method for coating a medical device with said suspension, and medical devices coated with at least one tri-O-acylglycerol and at least one microcrystalline taxane.Type: ApplicationFiled: November 16, 2021Publication date: March 14, 2024Applicant: HEMOTEQ AGInventors: Michael Hoffman, Erika Hoffmann, Günter Mathar
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Patent number: 11185614Abstract: The present invention relates to balloon catheters with or without crimped stent, whose surface is coated with at least one antirestenotic agent and at least one transport promoting molecular dispersant, as well as a method for the preparation of these medical devices.Type: GrantFiled: May 27, 2011Date of Patent: November 30, 2021Assignee: Hemoteq AGInventors: Erika Hoffmann, Michael Hoffmann, Roland Horres
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Patent number: 9968573Abstract: The present invention relates to an endoprosthesis with a drug coating comprising or consisting of at least one antibiotic agent and at least one further substance having the following generalType: GrantFiled: February 14, 2012Date of Patent: May 15, 2018Assignee: HEMOTEQ AGInventors: Erika Hoffmann, Michael Hoffmann, Roland Horres, Martin Erdtmann, Helmut Horbach
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Publication number: 20170014364Abstract: The present invention relates to an endoprosthesis with a drug coating comprising or consisting of at least one antibiotic agent and at least one further substance having the following generalType: ApplicationFiled: February 14, 2012Publication date: January 19, 2017Applicant: HEMOTEQ AGInventors: Erika Hoffmann, Michael Hoffmann, Roland Horres, Martin Erdtmann, Helmut Horbach
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Patent number: 9522219Abstract: The present invention is directed to stents made of a magnesium alloy degradable under physiological conditions and an outer polymeric coating. Herein, the stents according to the invention can be additionally coated with at least one anti-inflammatory, antiproliferative, antiangiogenic, antirestenotic and/or antithrombogenic active agent.Type: GrantFiled: August 15, 2012Date of Patent: December 20, 2016Assignees: HEMOTEQ AG, MEKO LASERSTRAHL-MATERIALBEARBEITUNGEN E.KInventors: Michael Stekker, Norbert Hort, Frank Feyerabend, Erika Hoffmann, Michael Hoffmann, Roland Horres
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Patent number: 9192697Abstract: The present invention is directed to a method for coating catheter balloons with a defined amount of a pharmacologically active agent, wherein the coating method uses a coating device having a volume measuring device for releasing a measurable amount of a coating solution by means of a dispensing device specifically onto the surface of the catheter balloon.Type: GrantFiled: February 9, 2011Date of Patent: November 24, 2015Assignee: Hemoteq AGInventors: Erika Hoffmann, Roland Horres, Volker Faust, Helmut Schreiber, Armin Von Holst, Michael Hoffmann
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Patent number: 8916227Abstract: The present invention relates to methods for coating the entire surface of lattice-like or mesh-like endoprostheses, wherein the endoprostheses initially are being provided with a thin layer covering the material surface of the endoprosthesis and subsequently, the surface of the entire endoprosthesis is being coated, wherein said coating of the entire surface covers the struts as well as the interstices between the individual struts.Type: GrantFiled: May 3, 2006Date of Patent: December 23, 2014Assignee: Hemoteq AGInventors: Roland Horres, Michael Hoffmann, Erika Hoffmann, Marita Linssen, Roger Caspers, Michaela Styrnik
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Patent number: 8784862Abstract: The invention concerns oligosaccharides and polysaccharides as well as the use of these oligosaccharides and/or polysaccharides, which contain the sugar unit N-acylglucosamine or N-acylgalactosamine for the production of hemocompatible surfaces as well as methods for the hemocompatible coating of surfaces with said oligosaccharides and/or polysaccharides, which imitate the common biosynthetic precursor substance of heparin, heparan sulphates and chitosan. The invention further describes methods for producing said oligosaccharides and/or polysaccharides and discloses various possibilities of using hemocompatibly coated surfaces. The invention relates particularly to the use of said oligosaccharides and/or polysaccharides on stents with at least one according to invention deposited hemocompatible coating, which contains an antiproliferative, antiinflammatory and/or antithrombotic active agent, methods for the preparation of said stents as well as the use of said stents for the prevention of restenosis.Type: GrantFiled: June 30, 2010Date of Patent: July 22, 2014Assignee: Hemoteq AGInventors: Roland Horres, Marita Katharina Linssen, Michael Hoffmann, Erika Hoffmann, Donate DiBiase, Volker Faust
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Publication number: 20140199365Abstract: The present invention is directed to stents made of a magnesium alloy degradable under physiological conditions and an outer polymeric coating. Herein, the stents according to the invention can be additionally coated with at least one anti-inflammatory, antiproliferative, antiangiogenic, antirestenotic and/or antithrombogenic active agent.Type: ApplicationFiled: August 15, 2012Publication date: July 17, 2014Applicants: HEMOTEQ AG, MEKO LASERSTRAHL-MATERIALBEARBEITUNGEN E.KInventors: Michael Stekker, Norbert Hort, Frank Feyerabend, Erika Hoffmann, Michael Hoffmann, Roland Horres
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Patent number: 8679520Abstract: The invention relates to stents with at least one hemocompatible coating which contains an antiproliferative, antiinflammatory and/or antithrombotic active agent, methods for the preparation of said stents as well as the use of said stents for the prevention of restenosis.Type: GrantFiled: October 15, 2002Date of Patent: March 25, 2014Assignee: Hemoteq AGInventors: Roland Horres, Michael Hoffmann, Erika Hoffmann, Donato Di Biase, Volker Faust
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Patent number: 8597720Abstract: A method for coating catheter balloons with a defined amount of a pharmacologically active agent, uses a coating device having a volume measuring device for releasing a measurable amount of a coating solution by means of a dispensing device specifically onto the surface of the catheter balloon.Type: GrantFiled: January 21, 2008Date of Patent: December 3, 2013Assignee: Hemoteq AGInventors: Erika Hoffmann, Roland Horres, Volker Faust, Helmut Schreiber, Armin Von Holst, Michael Hoffmann
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Publication number: 20130123695Abstract: The present invention relates to balloon catheters with or without crimped stent, whose surface is coated with at least one antirestenotic agent and at least one transport promoting molecular dispersant, as well as a method for the preparation of these medical devices.Type: ApplicationFiled: May 27, 2011Publication date: May 16, 2013Applicant: HEMOTEQ AGInventors: Erika Hoffmann, Michael Hoffmann, Roland Horres
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Publication number: 20130103139Abstract: The present invention relates to grid-like or net-like endoprosthesis having a continuous, respectively ongoing and interstices-spanning coating with a thread-tangle, wherein this continuous, respectively ongoing and interstices-spanning coating covers the struts as well as the interstices between the single endoprosthesis struts.Type: ApplicationFiled: May 27, 2011Publication date: April 25, 2013Applicant: HEMOTEQ AGInventors: Erika Hoffmann, Michael Hoffmann, Roland Horres, Lutz Freitag
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Publication number: 20110160698Abstract: The present invention is directed to a method for coating catheter balloons with a defined amount of a pharmacologically active agent, wherein the coating method uses a coating device having a volume measuring device for releasing a measurable amount of a coating solution by means of a dispensing device specifically onto the surface of the catheter balloon.Type: ApplicationFiled: February 9, 2011Publication date: June 30, 2011Applicant: HEMOTEQ AGInventors: Erika Hoffmann, Roland Horres, Volker Faust, Helmut Schreiber, Armin Von Holst, Michael Hoffmann
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Publication number: 20100063585Abstract: The invention relates to stents and catheter balloons having optimized coatings for eluting rapamycin as well as methods for manufacturing these coatings.Type: ApplicationFiled: July 3, 2007Publication date: March 11, 2010Applicant: HEMOTEQ AGInventors: Erika Hoffmann, Michael Hoffmann, Roland Horres, Sabine Küsters