Patents Assigned to HENAN UNIVERSITY
  • Patent number: 12276008
    Abstract: A tungsten-base alloy material and a preparation method therefor. The preparation method comprises: 1) evenly grinding composite powder containing tungsten and zirconium oxide, and then performing annealing treatment at 700-1000° C. to obtain powder A; and 2) grinding and then compression moulding the powder A, and then performing liquid-phase sintering to obtain a tungsten-base alloy blank so as to obtain the tungsten-base alloy material.
    Type: Grant
    Filed: August 12, 2020
    Date of Patent: April 15, 2025
    Assignee: HENAN UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Shizhong Wei, Liujie Xu, Fangnao Xiao, Kunming Pan, Yucheng Zhou, Xiuqing Li, Jiwen Li, Xiran Wang, Xiaodong Wang, Cheng Zhang, Chong Chen, Feng Mao, Mei Xiong, Guoshang Zhang, Dongliang Jin
  • Patent number: 12239039
    Abstract: An efficient transplanting device with an automatic seedling pick-up and supplementation function includes a seedling pick-up device, a seedling discharging device, and a seedling supplementation device. The seedling discharging device is used to discharge plug seedlings for transplantation; the seedling pick-up device is used to transfer the plug seedlings and the seedling supplementation device is used to supplement the plug seeding. A seedling pick-up photoelectric sensor, a detection camera, and a controller are provided for the operations of plug seedling pick-up, supplementation and discharge of the plug seedlings.
    Type: Grant
    Filed: September 6, 2024
    Date of Patent: March 4, 2025
    Assignee: Henan University of Science and Technology
    Inventors: Xin Jin, Qing Li, Shuang Chen, Xiaolin Xie, Shengsheng Wang, Liqiang Xiao, Mengnan Liu, Bo Zhao
  • Patent number: 12194072
    Abstract: A traditional Chinese medicine compound for preventing and treating African swine fever, its efficiency enhancement process, and application are provided, which relate to the field of fermentation technologies of traditional Chinese medicine by probiotics. A formula with the most apparent preventive and therapeutic effect on ASFV is obtained by comparing various traditional Chinese medicine prescriptions and self-drafted formulas, and the formula is made from Codonopsis pilosula, Atractylodes macrocephala, Wolfiporia cocos, Auckiandialappa Lappa Decne., Terminalia chebula, Aconitum carmichaeli, Myristica fragrans, Cynanchum otophyllum, Dioscorea polystachya and Ziziphus jujuba. Based on the formula, fermentation treatment of multi probiotics is performed, Bacillus subtilis, Saccharomyces cerevisiae, Bifidobacterium and Lactobacillus acidophilus are inoculated for fermenting, and a liquid fermented mixture is mixed to obtain fermentation preparation.
    Type: Grant
    Filed: June 7, 2024
    Date of Patent: January 14, 2025
    Assignee: Henan University of Chinese Medicine
    Inventors: Shuying Feng, Sugai Yin, Aifang Li, Baiyan Wang, Dandan Guo, Qianqian Wang, Yuqiang Zhang
  • Patent number: 12161700
    Abstract: The present disclosure provides a drug carrier, a brain-targeting nanodrug based on CRISPR gene editing technology and a preparation method and use thereof. The nanodrug contains nanoparticles prepared by coupling Cas9/sgRNA and drug carriers. The drug carrier includes a polymer mPEG-P (GPMA, FPMA) and a polymer Ang-PEG-PGPMA, wherein a structural formula of the mPEG-P (GPMA, FPMA) is: a structural formula of the polymer Ang-PEG-PGPMA is: where n is 35-45, x1 is 15-20, y is 2-4, m is 75-85, and x2=x1. The guanidino group of the drug carrier can be combined with the ribonucleoprotein complex by electrostatic action, salt bridge formation, or hydrogen bonding action. Also provided are methods of suppressing and treating tumors at a gene level using the drug carrier to transport the therapeutic drug to the lesion site.
    Type: Grant
    Filed: December 4, 2020
    Date of Patent: December 10, 2024
    Assignee: Henan University
    Inventors: Weimin Ruan, Mingzhu Jiao, Bingyang Shi, Meng Zheng
  • Patent number: 12156532
    Abstract: The present disclosure provides a peanut whole-process production line and a method. The peanut whole-process production line includes a peanut cleaning system, a shell breaking system, a skin removing system, a peanut kernel classification system, an ultra-fine pulverization system and a classification packaging system; a first procedure is cleaning and impurity removal of peanuts, breaking of peanut shells is performed after the cleaning and impurity removal of peanuts, removal of peanut kernel skins and ultra-fine pulverization of the peanut shells are respectively performed after the breaking of peanut shells, classification of peanut kernels is performed after the removal of peanut kernel skins, and classification packaging of ultra-fine peanut shell powder is performed after the ultra-fine pulverization of the peanut shells; whole-process processing of peanuts is completed by using the peanut whole-process production line, and peanut resources are fully utilized.
    Type: Grant
    Filed: May 9, 2020
    Date of Patent: December 3, 2024
    Assignees: QINGDAO UNIVERSITY OF TECHNOLOGY, RESEARCH INSTITUTE OF AGRICULTURAL MECHANIZATION, XINJIANG ACADEMY OF AGRICULTURAL SCIENCES, HENAN UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Mingzheng Liu, Changhe Li, Xinping Li, Xiangdong Liu, Huimin Yang, Yanbin Zhang, Xiaoming Wang, Yali Hou
  • Patent number: 12150468
    Abstract: An intelligent separation device has gas explosion, stirring, drying and negative pressure adsorption devices. The gas explosion device receives conveyed peanut materials with red coats to be removed, and the materials are subjected to gas explosion, so that the peanut kernels and the peanut red coats are preliminarily separated. The stirring device shifts the preliminarily separated peanut kernels and peanut red coats into the drying device. The drying device compresses and heating external air, transfers heat through hot air, and heats and dries the preliminarily separated peanut kernels and peanut red coats, so that the peanut red coats and the peanut kernels are fully separated. The negative pressure adsorption device collects the fully separated peanut kernels and red coats with different densities and masses in a negative pressure adsorption mode.
    Type: Grant
    Filed: May 8, 2020
    Date of Patent: November 26, 2024
    Assignees: QINGDAO UNIVERSITY OF TECHNOLOGY, HENAN UNIVERSITY OF SCIENCE AND TECHNOLOGY, RESEARCH INSTITUTE OF AGRICULTURAL MECHANIZATION, XINJIANG ACADEMY OF AGRICULTURAL SCIENCES
    Inventors: Mingzheng Liu, Changhe Li, Xinping Li, Xiangdong Liu, Huimin Yang, Yanbin Zhang, Xiaoming Wang, Yali Hou
  • Patent number: 12094198
    Abstract: A cloud platform-based garlic crop recognition method by coupling active and passive remote sensing images includes: firstly, obtaining an optical satellite remote sensing image based on phenological characteristics of garlic, and constructing a decision tree model for optical image recognition of the garlic by combining geographic coordinate information of the garlic, so as to obtain an optical distribution diagram of the garlic; secondly, obtaining radar image characteristics of the garlic and winter wheat based on a synthetic aperture radar satellite, and constructing a decision tree model for radar image recognition of the garlic by combining the geographic coordinate information of the garlic, so as to obtain a radar distribution diagram of the garlic; and finally, coupling the optical distribution diagram of the garlic with the radar distribution diagram of the garlic, i.e., selecting an intersection of the two distribution diagrams to complete remote sensing recognition drawing of the garlic.
    Type: Grant
    Filed: November 22, 2021
    Date of Patent: September 17, 2024
    Assignee: Henan University
    Inventors: Haifeng Tian, Yaochen Qin, Wei Shen, Boyan Zhou, Yongjiu Wang
  • Patent number: 12083491
    Abstract: A method for preparing the ferrous sulfide-containing passivator includes: dissolving a sulfide in an alkaline solution to form a mixed solution with a pH of 12-13; adding sodium silicate to the mixed solution and stirring for 0.5-1 hour at 20-40° C.; adding an aqueous solution of ferrous salt to the mixed solution containing sodium silicate, and allowing to react at 40-60° C. for 2-3 hours; where, with decrease of the pH of the mixed solution, sodium silicate is converted into silica nanoparticles, and the ferrous salt reacts with the sulfide to form ferrous sulfide; and further adding an aqueous solution of an organic modifier, and allowing to react at 40-60° C. for 1-2 hours to form a passivator slurry including surface-modified ferrous sulfide doped with silicon dioxide; filtering the passivator slurry to form a passivator.
    Type: Grant
    Filed: August 19, 2022
    Date of Patent: September 10, 2024
    Assignees: HENAN UNIVERSITY, ENGINEERING RESEARCH CENTER FOR NANOMATERIALS CO., LTD.
    Inventors: Chunpeng Song, Chaoran Li, Mingming Lian, Xiaohong Li, Zhijun Zhang
  • Patent number: 12076416
    Abstract: The present disclosure provides a gene editing nanocapsule and a preparation method and use thereof. The gene editing nanocapsule has a core-shell structure, wherein the inner core includes a Cas/sgRNA ribonucleoprotein complex, and the outer shell includes a polymer, the Cas/sgRNA ribonucleoprotein complex has a gene editing function, and the polymer acts as a carrier for the Cas/sgRNA ribonucleoprotein complex and protects it, because the polymer contains tumor microenvironment sensitive molecules, the nanocapsules can be efficiently released in tumor cells. Further, the surface of the outer shell can be modified with a targeting agent, so that the nanocapsule can specifically target tumor cells, which improves the endocytosis efficiency of the nanocapsule. The gene editing nanocapsule has good biocompatibility and biosafety, and is expected to become a safe and efficient gene therapy drug for tumors.
    Type: Grant
    Filed: February 18, 2022
    Date of Patent: September 3, 2024
    Assignee: Henan University
    Inventors: Yan Zou, Bingyang Shi, Meng Zheng, Xinhong Sun
  • Patent number: 12065717
    Abstract: The present disclosure relates to a preparation process of a Ti3AlC2 ceramic phase-toughened molybdenum alloy. The preparation process includes: mixing MoO2 and Ti3AlC2 powders, sieving to obtain a mixed powder, and then conducting high-temperature hydrogen reduction; mixing a resulting reduced powder with a coarse-grained Mo powder to obtain a precursor powder; putting the precursor powder into a cladding material to allow hot-pressed sintering; subjecting an obtained sintered molybdenum alloy to high-temperature treatment and thermoplastic processing in sequence; and annealing an obtained processed molybdenum alloy to obtain a high-strength and high-toughness molybdenum alloy. In the present disclosure, a Ti3AlC2-containing ultrafine powder prepared by reduction is mixed with the commercial coarse-grained molybdenum powder in a certain proportion to obtain the precursor powder.
    Type: Grant
    Filed: March 13, 2024
    Date of Patent: August 20, 2024
    Assignee: HENAN UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Shizhong Wei, Lu Yang, Xinyuan Zheng, Xiran Wang, Dong Liang, Yang Zhao
  • Patent number: 12053550
    Abstract: The present disclosure discloses preparation and use of sugar-targeting nanoparticles for modifying siRNA. A sugar-targeting nanoparticle, including targeting nanocarriers, wherein the targeting nanocarriers are formed by linking in sequence a targeting molecule, a first linking compound, a first hydrophilic biomaterial, a second linking compound and a cationic compound through chemical bonds; the first linking compound and the second linking compound both have a carboxyl group; the first linking compound has a maleimido group at the same time, and the targeting molecule is a cycloaldohexose.
    Type: Grant
    Filed: December 3, 2020
    Date of Patent: August 6, 2024
    Assignee: HENAN UNIVERSITY
    Inventors: Bingyang Shi, Feiyan Zhu, Meng Zheng, Yang Liu
  • Publication number: 20240188421
    Abstract: A solar cell is provided that comprises: a glass substrate or a plastic polymeric substrate; a first electrode disposed on the glass substrate or the plastic polymeric substrate, an electron transport layer disposed on the first electrode; a perovskite layer disposed on the electron transport layer; an organic-inorganic hole transport bilayer comprising an organic layer which is disposed on the perovskite layer and an inorganic layer which is disposed on the organic layer; and a second electrode disposed on the inorganic layer.
    Type: Application
    Filed: November 22, 2023
    Publication date: June 6, 2024
    Applicants: Henan University, Solaires Entreprises Inc.
    Inventors: Furui TAN, Yaqing LI, Wanlong WANG, Chen DONG
  • Patent number: 11985912
    Abstract: A weeding device for crops having a seedling avoidance function includes a rack connected to a weeding machine. A hydraulic pump and two hydraulic cylinders are mounted to the rack. Bottom ends of each of the two hydraulic cylinders are provided with a vertically arranged support rod. An inter-row weeder is mounted to a bottom end of each of the two support rods. A slider configured to reciprocate in a horizontal direction is positioned on two slide rails that are mounted to the rack. An inter-plant weeder is mounted to a bottom side of the slider. A plurality of weeder blades are arranged side by side on the inter-plant weeder. At the weeding position, an arrangement direction of weeder blades is perpendicular to an advancing direction, and at the weed avoidance position, the arrangement direction of the weeder blades is parallel to the advancing direction, thereby avoiding crops.
    Type: Grant
    Filed: November 22, 2023
    Date of Patent: May 21, 2024
    Assignee: Henan University of Science and Technology
    Inventors: Xin Jin, Hengyi Zhang, Hongbin Suo, Xiaowu Zhu, Mengnan Liu, Yirong Zhao, Bo Zhao
  • Patent number: 11980160
    Abstract: A dust removal-sterilization-deodorization integrated intelligent lightweight device for livestock and poultry houses includes: a transparent housing, a photocatalyst slidably connected to an inner wall of the transparent housing, filter sleeves rotatably mounted on the inner wall of the transparent housing, a flow guide cavity defined in the transparent housing, a fan fixedly connected to a left sidewall of the flow guide cavity, and a flow baffle fixedly connected to an air inlet end of the flow guide cavity. The filter sleeve includes a low-resistance melt-blown fabric, a rutile manganese-zinc layer is laid on an outer side of the low-resistance melt-blown fabric, a skeleton fabric is attached to an outer wall of the rutile manganese-zinc layer, and an outer wall of the skeleton fabric is rotatably connected to the inner wall of the transparent housing. At least two filter sleeves are transversely arranged, and the filter sleeves are tubular.
    Type: Grant
    Filed: November 19, 2023
    Date of Patent: May 14, 2024
    Assignees: Henan University of Animal Husbandry and Economy, GreenAsia Biotechnology Co., Ltd
    Inventors: Zhifang Shi, Lei Xi, Xuanyang Li, Pu Cheng, Chunhui Hua, Sixin Zhang, Limin Wang
  • Patent number: 11875488
    Abstract: A method for parallel processing of retinal images includes: optimizing an objective function with a chaotic supply-demand algorithm to enhance a real retinal image; synthesizing a virtual retinal image by a hybrid image generation method; establishing a parallel multi-layer decomposed interval type-2 intuitionistic fuzzy convolutional neural network model based on the virtual retinal image and the enhanced real retinal image; and integrating outputs from a plurality of parallel multi-layer decomposed interval type-2 intuitionistic fuzzy convolutional neural network models as a final classification result.
    Type: Grant
    Filed: April 13, 2021
    Date of Patent: January 16, 2024
    Assignee: HENAN UNIVERSITY OF TECHNOLOGY
    Inventors: Liang Zhao, Chuan Zhou, Xiaoxia Feng, Jingjing Li, Yuanyuan Liu, Ranran Si, Zhifeng Xie, Yuankun Fu, Junwei Jin, Kunpeng Zhang, Lei Zhang, Shimeng Shi, Tianci Wang, Dongjiang Liu, Meng Li, Zhiyuan Shi
  • Publication number: 20230340509
    Abstract: The present invention discloses a tomato glutaredoxin SIGRXC9 gene and its application. The present invention first identifies the tomato glutaredoxin SIGRXC9 gene, knock out of SIGRXC9 in tomato MT (micro-Tom) by Agrobacterium-mediated method for function identification and obtains a result that SIGRXC9 gene deletion results in tomato hypersensitivity to chilling stress, and reduced plant height, leaf length and width, which further demonstrates that SIGRXC9 plays an important role in controlling development and response to low-temperature stress.
    Type: Application
    Filed: December 15, 2022
    Publication date: October 26, 2023
    Applicants: Sanya Institute of Henan University, Henan University
    Inventors: Yingfang ZHU, Zhixin JIAO, Rui XU
  • Patent number: 11793764
    Abstract: The present disclosure provides an siRNA nanocapsule and a preparation method and use thereof, relating to the technical field of biomedical engineering. The siRNA nanocapsule provided in the present disclosure includes siRNA and a shell encapsulating the siRNA and polymerized by a monomer A and a monomer B. The monomer A has a double bond at one end, and is electrostatically bound with the siRNA, and the monomer B includes molecules for improving tumor microenvironment sensitivity. The siRNA nanocapsule provided in the present disclosure is suitable for a wide range of clinical applications.
    Type: Grant
    Filed: December 4, 2020
    Date of Patent: October 24, 2023
    Assignee: HENAN UNIVERSITY
    Inventors: Bingyang Shi, Yan Zou
  • Publication number: 20230281806
    Abstract: A microbubble counting method for patent foramen ovale (PFO) based on deep learning is provided. The method includes: segmenting a target area of a left heart in an ultrasonic image; and generating a corresponding density map for a segmented target image using a convolutional neural network (CNN), and calculating a total number of the microbubbles in the segmented area by integration and summation. The method has the following beneficial effects: target segmentation is performed on the left atrium and left ventricular area of the heart using the neural network, and effective segmentation of the target area of the left heart is the key of obtaining parameters such as a size and form of the target area. The target area is quantitatively analyzed according to a segmentation result, and the number of the microbubbles in the target area is counted.
    Type: Application
    Filed: February 28, 2023
    Publication date: September 7, 2023
    Applicant: Henan University of Science and Technology
    Inventors: Mingchuan ZHANG, Mengjie GU, Lin WANG, Qingtao WU, Junlong ZHU, Zhihang JI
  • Patent number: 11734923
    Abstract: A method for automatically identifying global solar photovoltaic (PV) panels based on a cloud platform by using remote sensing. Optical images in a study area for a whole specific year are collected based on the cloud platform, and preprocessing is performed to obtain a surface reflectance image. Seven time-series images are derived and constructed based on spectral features of a solar PV panel: a solar PV panel index image, a water index image, a vegetation index image, a difference image between a first shortwave infrared band and a second shortwave infrared band, a difference image between the first shortwave infrared band and a near-infrared band, a blue band image, and a first shortwave infrared band image. Data in the seven time-series images are synthesized and reconstructed to obtain input data required by a model. A remote sensing theoretical model for automatically identifying a solar PV panel is constructed.
    Type: Grant
    Filed: January 20, 2023
    Date of Patent: August 22, 2023
    Assignee: Henan University
    Inventors: Haifeng Tian, Jiajun Qiao, Yaochen Qin, Xiaohao Jiao, Shuai Wang
  • Patent number: 11717813
    Abstract: A method for preparing a zeolite catalyst for catalytic cracking of hydrocarbons to produce propylene is provided, which specifically includes steps of mixing a silicon source, a templating agent, an aluminium source, and a solvent to form a zeolite precursor solution, which is then subjected to hydrothermal crystallization, washing, drying, and calcination to obtain a zeolite precursor; ion-exchanging the zeolite precursor with ammonium ions, followed by drying and calcination; and loading aluminum onto the ion-exchanged zeolite precursor as a carrier via incipient-wetness impregnation by using an aluminium-containing solution, followed by drying and calcination. Zeolite catalysts prepared by the method and use of the catalysts in catalytic cracking of hydrocarbons to produce propylene are also provided.
    Type: Grant
    Filed: August 18, 2022
    Date of Patent: August 8, 2023
    Assignee: Henan University
    Inventors: Yajie Tian, Xinyu He, Congzhen Qiao