Patents Assigned to Henkel Konnarditgesellshaft auf Aktien
  • Mutant proteolytic enzymes and method of production
    Patent number: 6403331
    Abstract: Mutant Bacillus lentus DSM 5483 proteases are derived by the replacement of at least one amino acid residue of the mature form of the B. lentus DSM 5483 alkaline protease. The mutant proteases are expressed by genes which are mutated by site-specific mutagenesis. The amino acid sites selected for replacement are identified by means of a computer based method which compares the three dimensional structure of the wild-type protease and a reference protease.
    Type: Grant
    Filed: May 31, 2000
    Date of Patent: June 11, 2002
    Assignee: Henkel Konnarditgesellshaft auf Aktien
    Inventors: Teresa Christianson, Dean Goddette, Beth Frances Ladin, Maria R. Lau, Christian Paech, Robert B. Reynolds, Charles R. Wilson, Shiow-Shong Yang