Abstract: Stable forms of Taenia ovis peptide antigens, such as portions of a T. ovis oncosphere antigen which runs as a 47-52 kDa doublet, are suitable for use in vaccines to protect ruminants against infection by cestode parasites. The antigens are preferably obtained by isolation and expression of the DNA encoding them in recombinant host cells. Aspects of the invention include DNA encoding T. ovis antigens, vectors containing such DNA and host cells which express the T. ovis antigens.
Type:
Grant
Filed:
October 30, 1992
Date of Patent:
November 22, 1994
Assignees:
Pitman-Moore New Zealand Limited, The University of Melbourne, Her Majestry the Queen in right of New Zealand through the Ministry of Agriculture & Fisheries
Inventors:
Gavin B. L. Harrison, Robert P. Dempster, Michael D. Rickard, Marshall W. Lightowlers, David D. Heath, Stephen B. Lawrence, Kim L. O'Hoy