Abstract: The present invention relates to a novel polymeric material with enhanced hydrophilicity for medical use comprising a biocompatible polyester material selected from the group consisting of poly(hydroxyalkanoate)s, poly(lactic acid)s, poly(glycolic acid)s, poly(caprolactone)s and copolymers and blends thereof, wherein the biocompatible polyester material is crosslinked with a functionalized poly(alkylene oxide) having at least two functional groups independently selected from the group consisting of azido-formate and alkanoyl azide. The novel polymeric material with enhanced hydrophilicity is useful as a biocompatible material in a variety of medical applications, including medical implants, bioresorbable implants, tissue engineering, and controlled release.
Type:
Grant
Filed:
June 20, 2012
Date of Patent:
February 24, 2015
Assignees:
Technische Universitat Graz, Medical University of Graz MUG, AT&S Austria Technologie & Systemtechnik Aktiengesellschaft, Herabus Medical GmbH
Inventors:
Frank Wiesbrock, Clemens Ebner, Franz Stelzer, Annelie-Martina Weinberg, Klaus-Dieter Kühn