Patents Assigned to Hexal AG
  • Solid, non-deliquescent formulations of sodium valproate
    Patent number: 6204255
    Abstract: Non-deliquescent formulation comprising or consisting of sodium valproate and cyclodextrin having a molar ratio of sodium valproate to cyclodextrin within the range of from 1:0.01 to 1:0.09.
    Type: Grant
    Filed: May 24, 1999
    Date of Patent: March 20, 2001
    Assignee: Hexal AG
    Inventor: Karin Klokkers
  • Transdermal preparation containing a loratidine metabolite with antihistaminic activity
    Patent number: 6165498
    Abstract: A transdermal patch contains an active loratidine metabolite contained with a polyacrylate polymer matrix. The transdermal patch provides pharmaceutically useful transdermal flux rates over time.
    Type: Grant
    Filed: March 23, 1998
    Date of Patent: December 26, 2000
    Assignee: Hexal AG
    Inventors: Karin Klokkers, Wilfried Fischer, Daniel Bracher
  • Diclofenac/gamma-cyclodextrin inclusion compounds
    Patent number: 6071964
    Abstract: The object of the present invention is an oral drug preparation containing the .gamma.-cyclodextrin complex of diclofenac or pharmaceutically acceptable salts thereof, especially the sodium salt prepared by known methods, and by which the gastro-intestinal irritancy of diclofenac, at the same or improved bioavailability, can be considerably decreased.
    Type: Grant
    Filed: May 11, 1999
    Date of Patent: June 6, 2000
    Assignee: Hexal AG
    Inventors: Wilfried Fischer, Anna Sendl-Lang
  • Pharmaceutical composition containing cyclosporin A
    Patent number: 6022852
    Abstract: The invention relates to a pharmaceutical composition consisting of or containing cyclosporin A and .alpha.-tocopherol or one of the derivatives thereof.
    Type: Grant
    Filed: May 11, 1998
    Date of Patent: February 8, 2000
    Assignee: Hexal AG
    Inventors: Karin Klokkers, Wilfried Fischer
  • Transdermal therapeutic system (TTS) containing vitamin E for the treatment of drug dependency
    Patent number: 5989585
    Abstract: The invention relates to a transdermal therapeutic system (TTS) for the administration of active agents for substitution treatment of drug dependency or drug addiction.
    Type: Grant
    Filed: June 23, 1998
    Date of Patent: November 23, 1999
    Assignee: Hexal AG
    Inventor: Daniel Bracher
  • Tablet or capsule having a content of stable ranitidine hydrochloride form 1
    Patent number: 5910320
    Abstract: The invention relates to a tablet or capsule that is characterised by a powder mixture having a content of stable ranitidine hydrochloride Form 1 together with a carrier and/or diluent, and to manufacturing processes for the tablet.
    Type: Grant
    Filed: August 19, 1996
    Date of Patent: June 8, 1999
    Assignee: Hexal AG
    Inventors: Wilfried Fischer, Karin Klokkers
  • Transdermal system in the form of a patch comprising a tamoxifen derivative
    Patent number: 5904930
    Abstract: A transdermal system in the form of a patch that comprises a tamoxifen derivative and an absorption-promoting additive for systemic administration.
    Type: Grant
    Filed: September 5, 1997
    Date of Patent: May 18, 1999
    Assignee: Hexal AG
    Inventors: Wilfried Fischer, Karin Klokkers, Anna Sendl-Lang
  • Sustained release tablet containing diclofenac-Na and methylhydroxypropyl-cellulose as a sustained release agent
    Patent number: 5874107
    Abstract: The invention relates to a sustained release tablet containing diclofenac-Na as active material and methylhydroxypropylcellulose as sustained release agent.
    Type: Grant
    Filed: September 11, 1996
    Date of Patent: February 23, 1999
    Assignee: Hexal AG
    Inventors: Wilfried Fischer, Karin Klokkers
  • Thyroxine/cyclodextrin complexes and pharmaceutical compositions containing the same
    Patent number: 5856359
    Abstract: Thyroxine containing pharmaceutical compositions with improved aqueous solubility, stability and enhanced membrane permeation have been prepared by formulating thyroxine with cyclodextrins. These thyroxine/cyclodextrin complexes can further be transformed into different dosage forms (oral tablets, injectables, transdermal patches, hydrogels, ointments, suppositories etc.) by employing known, common pharmaceutical additives.
    Type: Grant
    Filed: July 24, 1997
    Date of Patent: January 5, 1999
    Assignee: Hexal AG
    Inventors: Wilfried Fischer, Daniel Bracher