Patents Assigned to Hexal Pharmaceuticals, Inc.
  • Process for preparing form 1 ranitidine hydrochloride
    Patent number: 5663381
    Abstract: A process for preparing pure N-[2-[[[5-[dimethylamino)-methyl-2-furanyl]methyl]thio]ethyl]-N'-methyl-2- nitro-1,1-ethyldiamine hydrochloride, designated Form 1 ranitidine hydrochloride, from ranitidine in methylene chloride with the addition of hydrochloric acid. The Form 1 ranitidine hydrochloride thus obtained is stable and therefore useful for producing commercial-scale quantities of Form 1 ranitidine hydrochloride.
    Type: Grant
    Filed: April 21, 1995
    Date of Patent: September 2, 1997
    Assignee: Hexal Pharmaceuticals, Inc.
    Inventors: Helmut Schickaneder, Aggelos Nikolopoulos