Abstract: The invention relates to the use of galanthamine, as free base or as acid addition salt, for the treatment of cerebral, central nervous or psychiatric symptoms, defunctionalization manifestations or disorders occurring through intake of psychotropic substances as a consequence of occasional or chronic abuse of addictive substances, intoxicants or medicines, or as side effects of the use, especially repeated or prolonged, as intended of medicaments, or as an effect of use, in particular repeated or prolonged, not as intended of medicaments, or as a result of acute poisoning by psychotropic toxic substances, or as a result of chronic exposure to toxic substances with a psychotropic effect in humans or other vertebrates.
Type:
Grant
Filed:
April 18, 2002
Date of Patent:
June 26, 2012
Assignee:
HF Arzneimittelforschung GmbH
Inventors:
Klaus Opitz, Joachim Moormann, Thomas Hille, Frank Becher
Abstract: Processes for the production of a compound of the following formula (I) by converting a compound of formula (II) with 2-pyrrolidone used in excess relative to compound (II) and processes for the production of a compound of formula (III). The latter process includes preparing compound (I); a reduction reaction which yields compound (III) in salt form; and liberating compound (III) from the salt.
Type:
Grant
Filed:
January 22, 2004
Date of Patent:
February 24, 2009
Assignee:
HF Arzneimittelforschung GmbH
Inventors:
Joachim Moormann, Hans-Rainer Hoffmann, Rudolf Matusch
Abstract: Film-shaped medicaments administered orally, particularly buccally, for treating climacteric complaints. The medicaments contain estriol and/or at least one pharmacologically acceptable ester of estriol, either alone or in combination with at least one gestagen.
Abstract: Processes for the production of a compound of the following formula (I) by converting a compound of formula (II) with 2-pyrrolidone used in excess relative to compound (II) and processes for the production of a compound of formula (III). The latter process includes preparing compound (I); a reduction reaction which yields compound (III) in salt form; and liberating compound (III) from the salt.
Type:
Application
Filed:
January 22, 2004
Publication date:
April 20, 2006
Applicant:
HF Arzneimittelforschung GmbH
Inventors:
Joachim Moormann, Hans-Rainer Hoffmann, Rudolf Matusch