Abstract: The invention provides humanized monoclonal antibodies against Gal9, and method of using the antibodies to treat cancer, including combination therapy with antagonists of the PD-1/PD-L1 immune checkpoint.
Type:
Grant
Filed:
January 6, 2021
Date of Patent:
June 9, 2026
Assignee:
HIFIBIO, INC.
Inventors:
Germain Margall Ducos, Rachel Pacherie, Nicola Arturo Aldo Beltraminelli, Francisco Adrian, Liang Schweizer, Muriel David, Yun-Yueh Lu
Abstract: Anti-CCR8 antibodies and antigen-binding fragments thereof are described herein. Also described herein are nucleic acids encoding the anti-CCR8 antibodies and antigen-binding fragments thereof, compositions comprising the anti-CCR8 antibodies and antigen-binding fragments thereof, and methods of producing and using the anti-CCR8 antibodies and antigen-binding fragments thereof for treating or preventing cancer in a subject in need thereof.
Type:
Application
Filed:
August 19, 2022
Publication date:
January 16, 2025
Applicant:
HIFIBIO, INC.
Inventors:
Julie PRIGENT, Nicola Arturo Aldo BELTRAMINELLI, Sami ELLOUZE, Francisco ADRIAN, Liang SCHWEIZER, Yun-Yueh LU, Ross Bane FULTON