Patents Assigned to High Point Pharmacueticals, LLC
  • 11?-hydroxysteroid dehydrogenase type 1 active spiro compounds
    Patent number: 8138342
    Abstract: A novel class of compounds of the general formula (I), their use in therapy, pharmaceutical compositions comprising the compounds, as well as their use in the manufacture of medicaments are described. The present compounds modulate the activity of 11 ?-hydroxy-Steroid dehydrogenase type 1 (11?HSD1) and are accordingly useful in the treatment of diseases in which such a modulation is beneficial, e.g. the metabolic syndrome.
    Type: Grant
    Filed: October 12, 2005
    Date of Patent: March 20, 2012
    Assignee: High Point Pharmacueticals, LLC
    Inventors: John Paul Kilburn, Henrik Sune Andersen, Gita Camilla Tejlgaard Kampen