Patents Assigned to HIGHLIFE SAS
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Publication number: 20200078170Abstract: A transcatheter atrio-ventricular valve prosthesis for functional replacement of an atrio-ventricular valve in a connection channel, having a circumferential connection channel wall structure, between atrial and ventricular chambers of a heart, including an inner device to be disposed in the interior of the connection channel, the inner device having a circumferential support structure which is radially expandable and having a valve attached to the circumferential support structure, and an outer device to be disposed on the exterior of the connection channel, wherein the outer device at least partly extends around the inner device at a radial distance to the inner device, wherein the inner and outer devices form a securing mechanism for securing the circumferential connection channel wall structure therebetween.Type: ApplicationFiled: November 15, 2019Publication date: March 12, 2020Applicant: HIGHLIFE SASInventor: Josef WEBER
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Publication number: 20200078171Abstract: A transcatheter atrio-ventricular valve prosthesis for functional replacement of an atrio-ventricular valve in a connection channel, having a circumferential connection channel wall structure, between atrial and ventricular chambers of a heart, including an inner device to be disposed in the interior of the connection channel, the inner device having a circumferential support structure which is radially expandable and having a valve attached to the circumferential support structure, and an outer device to be disposed on the exterior of the connection channel, wherein the outer device at least partly extends around the inner device at a radial distance to the inner device, wherein the inner and outer devices form a securing mechanism for securing the circumferential connection channel wall structure therebetween.Type: ApplicationFiled: November 15, 2019Publication date: March 12, 2020Applicant: HIGHLIFE SASInventor: Josef WEBER
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Publication number: 20200046499Abstract: A catheter member for interacting with a circumferential tissue structure includes: an elongate primary catheter having at least one inner lumen and extending along a longitudinal axis; first and second elongate secondary catheters, each having an inner lumen, and each positionable in an inner lumen of the primary catheter to be moveable relatively thereto and exposable therefrom; and a first flexing mechanism to provide a distal end portion of the first and/or second secondary catheter with a tendency to assume a first secondary bent shape. The distal end portion of the first and/or second secondary catheters is provided so as to be able to be flexed by the first flexing mechanism to form an arm portion substantially transverse to the direction of the longitudinal axis of the primary catheter so as to assume the first secondary bent shape when exposed from a distal end portion of the primary catheter.Type: ApplicationFiled: October 10, 2019Publication date: February 13, 2020Applicant: HIGHLIFE SASInventors: Georg BORTLEIN, Malek NASR
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Publication number: 20200008940Abstract: A heart valve system, the system including a radially self-expandable tubular body and a valve. The tubular body having an inflow end and an outflow end, and the tubular body including a proximal-most end at the inflow end and a distal-most end at the outflow end. The tubular body including a plurality of arched beams at the outflow end of the tubular body such that the arched beams form the distal-most end of the tubular body. Connection points linking the inflow end of the tubular body and the arched beams, a number of connection points being equivalent to a number of the valve leaflets. Each arched beam being directly attached to an adjacent arched beam such that the arched beams are continuous along the entire circumference of the tubular body at the outflow end. The valve being coupled to the tubular body and including a plurality of valve leaflets.Type: ApplicationFiled: September 19, 2019Publication date: January 9, 2020Applicant: HIGHLIFE SASInventor: Malek NASR
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Patent number: 10470884Abstract: A catheter member for interacting with a circumferential tissue structure includes: an elongate primary catheter having at least one inner lumen and extending along a longitudinal axis; first and second elongate secondary catheters, each having an inner lumen, and each positionable in an inner lumen of the primary catheter to be moveable relatively thereto and exposable therefrom; and a first flexing mechanism to provide a distal end portion of the first and/or second secondary catheter with a tendency to assume a first secondary bent shape. The distal end portion of the first and/or second secondary catheters is provided so as to be able to be flexed by the first flexing mechanism to form an arm portion substantially transverse to the direction of the longitudinal axis of the primary catheter so as to assume the first secondary bent shape when exposed from a distal end portion of the primary catheter.Type: GrantFiled: March 2, 2017Date of Patent: November 12, 2019Assignee: HIGHLIFE SASInventors: Georg Bortlein, Malek Nasr
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Patent number: 10456247Abstract: A heart valve system, the system including a radially self-expandable tubular body and a valve. The tubular body having an inflow end and an outflow end, and the tubular body including a proximal-most end at the inflow end and a distal-most end at the outflow end. The tubular body including a plurality of arched beams at the outflow end of the tubular body such that the arched beams form the distal-most end of the tubular body. Connection points linking the inflow end of the tubular body and the arched beams, a number of connection points being equivalent to a number of the valve leaflets. Each arched beam being directly attached to an adjacent arched beam such that the arched beams are continuous along the entire circumference of the tubular body at the outflow end. The valve being coupled to the tubular body and including a plurality of valve leaflets.Type: GrantFiled: November 4, 2016Date of Patent: October 29, 2019Assignee: HIGHLIFE SASInventor: Malek Nasr
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Patent number: 10195027Abstract: A heart valve system, the system including a radially self-expandable tubular body and a valve. The tubular body having an inflow end and an outflow end such that the outflow end includes a proximal section and a plurality of beams. The plurality of beams being disposed distally of the proximal section in an outflow direction. Additionally, the tubular body including struts with peaks and valleys at the inflow end of the tubular body such that the proximal section of the outflow end is disposed distally of the peaks and valleys in the outflow direction. Furthermore, the tubular body being configured such that movement of the proximal section of the outflow end radially inward causes the inflow end to flare radially outward, and an arrangement of the struts being configured such that movement of the peaks radially inward causes the valleys to flare radially outward.Type: GrantFiled: November 4, 2016Date of Patent: February 5, 2019Assignee: HIGHLIFE SASInventor: Malek Nasr
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Patent number: 10195031Abstract: An implant for implantation around a circumferential tissue structure in a heart, includes a flexible elongated component having a longitudinal axis and a first distal end portion, a second distal end portion and an intermediate portion extending between the first and second distal end portions, and an inner lumen extending longitudinally between the first and second distal end portions and through the intermediate portion; and a locking member for allowing the first distal end portion to be fixedly connected to the second distal end portion so as to provide the elongated component as a closed loop. The first distal end portion is provided with a first distal opening which connects the inner lumen with an outside of the component. The second distal end portion is provided with a second distal opening which connects the inner lumen with the outside of the component.Type: GrantFiled: May 3, 2016Date of Patent: February 5, 2019Assignee: HIGHLIFE SASInventors: Malek Nasr, Georg Börtlein, Jean-Francois Ollivier, Philippe D'Hiver
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Patent number: 10188514Abstract: A heart valve system, the system including a radially self-expandable tubular body, a valve, and a tubular fabric. The tubular body having an inflow end and an outflow end. The valve being coupled to the tubular body and including a plurality of valve leaflets. The valve leaflet being supported by only two beams of the plurality of beams, and connection points linking the inflow end of the tubular body and the plurality of beams. A number of connection points being equivalent to a number of the valve leaflets. Additionally, each beam of the plurality of beams being directly connected to an adjacent beam so that the plurality of beams extends the entire circumferential length of the tubular body at the outflow end.Type: GrantFiled: November 4, 2016Date of Patent: January 29, 2019Assignee: HIGHLIFE SASInventor: Malek Nasr
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Patent number: 10080651Abstract: A system for implanting a heart valve includes a radially self-expandable tubular body having an inflow end and an outflow end and a preformed groove disposed at an outer surface of the tubular body between the inflow end and the outflow end. The preformed groove extends at least partially around the tubular body and has a circumferential opening facing radially outward of the tubular body. A valve is disposed within and is attached to the tubular body, and an elongate outer member is configured to form a loop encircling the preformed groove so as to guide portions of native valve leaflets and/or chords into the preformed groove. The outflow end of the tubular body includes a frustoconical shape that slopes radially outward from the preformed groove toward the outflow end when the outflow end but not the inflow end has been released from a delivery catheter.Type: GrantFiled: March 11, 2014Date of Patent: September 25, 2018Assignee: HIGHLIFE SASInventors: Georg Börtlein, Malek Nasr
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Patent number: 10064719Abstract: A system for implanting a heart valve includes a radially self-expandable tubular body having an inflow end and an outflow end and a projection extending from a side surface of the tubular body toward the inflow end. The system further includes a valve disposed within and attached to the tubular body, and may include fabric that forms a pouch between the tubular body and the projection.Type: GrantFiled: March 11, 2014Date of Patent: September 4, 2018Assignee: HIGHLIFE SASInventors: Georg Börtlein, Malek Nasr
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Publication number: 20180193140Abstract: A transcatheter atrio-ventricular valve prosthesis for functional replacement of an atrio-ventricular valve in a connection channel, having a circumferential connection channel wall structure, between atrial and ventricular chambers of a heart, including an inner device to be disposed in the interior of the connection channel, the inner device having a circumferential support structure which is radially expandable and having a valve attached to the circumferential support structure, and an outer device to be disposed on the exterior of the connection channel, wherein the outer device at least partly extends around the inner device at a radial distance to the inner device, wherein the inner and outer devices form a securing mechanism for securing the circumferential connection channel wall structure therebetween.Type: ApplicationFiled: January 31, 2018Publication date: July 12, 2018Applicant: HIGHLIFE SASInventor: Josef WEBER
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Patent number: 9999502Abstract: A heart valve system, the system including a radially self-expandable tubular body, a valve, and a tubular fabric. The tubular body having an inflow end and an outflow end and including a plurality of struts with at least one motion buffer component integrated in the tubular body. The valve being coupled to the tubular body and including a plurality of valve leaflets. The fabric being disposed over an outer surface of the tubular body and over an outer surface of the motion buffer component. Additionally, when the outflow end of the tubular body moves radially inward from movement of the valve leaflets, the motion buffer component being configured so as to not move radially inward with the outflow end of the tubular body.Type: GrantFiled: November 4, 2016Date of Patent: June 19, 2018Assignee: HIGHLIFE SASInventor: Malek Nasr
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Publication number: 20180161156Abstract: A heart valve system, the system including a radially self-expandable tubular body, a valve, and a tubular fabric. The tubular body having an inflow end and an outflow end. The valve being coupled to the tubular body and including a plurality of valve leaflets. The fabric being disposed on an outer surface of the tubular body, and the fabric having an inflow end and an outflow end, Furthermore, the outflow end of the fabric being directly connected to an outer circumferential edge of the valve.Type: ApplicationFiled: January 30, 2018Publication date: June 14, 2018Applicant: HIGHLIFE SASInventor: Malek NASR
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Publication number: 20180125649Abstract: A heart valve system, the system including a radially self-expandable tubular body, a valve, and a tubular fabric. The tubular body having an inflow end and an outflow end. The valve being coupled to the tubular body and including a plurality of valve leaflets. The fabric being disposed on an outer surface of the tubular body, and the fabric having an inflow end and an outflow end. Furthermore, the outflow end of the fabric being directly connected to an outer circumferential edge of the valve.Type: ApplicationFiled: November 4, 2016Publication date: May 10, 2018Applicant: HIGHLIFE SASInventor: Malek NASR
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Publication number: 20180125648Abstract: A heart valve system, the system including a radially self-expandable tubular body, a valve, and a tubular fabric. The tubular body having an inflow end and an outflow end and including a plurality of struts with at least one motion buffer component integrated in the tubular body. The valve being coupled to the tubular body and including a plurality of valve leaflets. The fabric being disposed over an outer surface of the tubular body and over an outer surface of the motion buffer component. Additionally, when the outflow end of the tubular body moves radially inward from movement of the valve leaflets, the motion buffer component being configured so as to not move radially inward with the outflow end of the tubular body.Type: ApplicationFiled: November 4, 2016Publication date: May 10, 2018Applicant: HIGHLIFE SASInventor: Malek NASR
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Publication number: 20180125650Abstract: A heart valve system, the system including a radially self-expandable tubular body and a valve. The tubular body having an inflow end and an outflow end such that the outflow end includes a proximal section and a plurality of beams. The plurality of beams being disposed distally of the proximal section in an outflow direction. Additionally, the tubular body including struts with peaks and valleys at the inflow end of the tubular body such that the proximal section of the outflow end is disposed distally of the peaks and valleys in the outflow direction. Furthermore, the tubular body being configured such that movement of the proximal section of the outflow end radially inward causes the inflow end to flare radially outward, and an arrangement of the struts being configured such that movement of the peaks radially inward causes the valleys to flare radially outward.Type: ApplicationFiled: November 4, 2016Publication date: May 10, 2018Applicant: HIGHLIFE SASInventor: Malek NASR
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Publication number: 20180125647Abstract: A heart valve system, the system including a radially self-expandable tubular body, a valve, and a tubular fabric. The tubular body having an inflow end and an outflow end. The valve being coupled to the tubular body and including a plurality of valve leaflets. The valve leaflet being supported by only two beams of the plurality of beams, and connection points linking the inflow end of the tubular body and the plurality of beams. A number of connection points being equivalent to a number of the valve leaflets. Additionally, each beam of the plurality of beams being directly connected to an adjacent beam so that the plurality of beams extends the entire circumferential length of the tubular body at the outflow end.Type: ApplicationFiled: November 4, 2016Publication date: May 10, 2018Applicant: HIGHLIFE SASInventor: Malek NASR
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Publication number: 20180125651Abstract: A heart valve system, the system including a radially self-expandable tubular body and a valve. The tubular body having an inflow end and an outflow end, and the tubular body including a proximal-most end at the inflow end and a distal-most end at the outflow end. The tubular body including a plurality of arched beams at the outflow end of the tubular body such that the arched beams form the distal-most end of the tubular body. Connection points linking the inflow end of the tubular body and the arched beams, a number of connection points being equivalent to a number of the valve leaflets. Each arched beam being directly attached to an adjacent arched beam such that the arched beams are continuous along the entire circumference of the tubular body at the outflow end. The valve being coupled to the tubular body and including a plurality of valve leaflets.Type: ApplicationFiled: November 4, 2016Publication date: May 10, 2018Applicant: HIGHLIFE SASInventor: Malek NASR
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Publication number: 20180116799Abstract: An implant for implantation around a circumferential tissue structure in a heart, includes a flexible elongated component having a longitudinal axis and a first distal end portion, a second distal end portion and an intermediate portion extending between the first and second distal end portions, and an inner lumen extending longitudinally between the first and second distal end portions and through the intermediate portion; and a locking member for allowing the first distal end portion to be fixedly connected to the second distal end portion so as to provide the elongated component as a closed loop. The first distal end portion is provided with a first distal opening which connects the inner lumen with an outside of the component. The second distal end portion is provided with a second distal opening which connects the inner lumen with the outside of the component.Type: ApplicationFiled: May 3, 2016Publication date: May 3, 2018Applicant: HIGHLIFE SASInventors: Malek NASR, Georg BÖRTLEIN, Jean-Francois OLLIVIER, Philippe D'HIVER