Abstract: Provided is a medicated patch containing a medicinal agent, an adhesive base material and a tackifier, where the medicinal agent is varenicline or a pharmaceutically acceptable salt thereof, the adhesive base material is a rubbery adhesive base material and the tackifier is a rosin-based tackifier selected from the group consisting of rosin, rosin derivatives and hydrogenated products of the foregoing, or a non-rosin-based tackifier selected from the group consisting of aliphatic hydrocarbon resins and alicyclic hydrocarbon resins, and when a non-rosin-based tackifier is added as the tackifier, a solubilizer for the medicinal agent is further added, the solubilizer containing an alcohol-based solubilizer having at least a solubility parameter of 20-35.
Type:
Grant
Filed:
February 9, 2009
Date of Patent:
October 28, 2014
Assignee:
Hisamitso Pharmaceutical Co., Inc.
Inventors:
Naoki Yamamoto, Kumi Morimoto, Akio Takeuchi, Kenji Ishigaki