Abstract: With the present invention, glycoalbumin and hemoglobin A1c are measured in a blood sample, and the incidence of or the existence or non-existence of a development risk of Alzheimer's disease can then be determined based on the calculated glycoalbumin/hemoglobin A1c ratio. Compounds for treating or preventing Alzheimer's disease can also be selected using this glycoalbumin/hemoglobin A1c ratio.
Type:
Application
Filed:
November 2, 2017
Publication date:
August 29, 2019
Applicants:
KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION, HISAYAMA RESEARCH INSTITUTE FOR LIFESTYLE DISEASES
Abstract: A test method for diagnosing cerebral infarction, a test method for diagnosing the disease type of cerebral infarction, and a test method for predicting prognosis of cerebral infarction in a subject animal, which test methods comprise the step of measuring the amount of cartilage acidic protein 1 in a blood sample collected from the animal.
Type:
Application
Filed:
May 16, 2013
Publication date:
September 26, 2013
Applicants:
MITSUBISHI CHEMICAL CORPORATION, HISAYAMA RESEARCH INSTITUTE FOR LIFESTYLE DISEASES, KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION
Abstract: Two genes implicated in arteriosclerotic diseases such as cerebral infarction were successfully identified by performing genome-wide correlation studies using SNPs by targeting the entire genome. Polymorphic mutations that can be used to examine the presence or absence of risk factors for arteriosclerotic diseases were successfully found on the genes. Subjects can be efficiently examined for the presence or absence of risk factors for arteriosclerotic diseases using the presence or absence of the polymorphic mutations as indicators. Furthermore, methods of screening for therapeutic agents for arteriosclerotic diseases are enabled by using expression or function of the genes as index.
Type:
Application
Filed:
April 24, 2007
Publication date:
December 31, 2009
Applicants:
KYUSHU UNIVERISTY, NATIONAL UNIVERSITY CORPORATION, THE UNIVERSITY TOKYO, HISAYAMA RESEARCH INSTITUTE FOR LIFESTYLE DISEASES, NTT DATA CORPORATION, HUBIT GENOMIX, INC
Inventors:
Yutaka Kiyohara, Mitsuo Iida, Setsuro Ibayashi, Michiaki Kubo, Jun Hata, Yusuke Nakamura, Teruo Omae, Yasuhiro Tanaka, Go Ichien