Abstract: Reconfigurable microfluidic systems are based on networks of microfluidic cavities connected by hydrophobic microfluidic channels. Each cavity is classified as either a reservoir or a node, and includes a pressure port via which gas pressure may be applied. Sequences of gas pressures, applied to reservoirs and nodes according to a fluid transfer rule, enable fluid to be moved from any reservoir to any other reservoir in a system. Such systems are suitable for automated, multi-input, multi-output homogeneous assays.
Type:
Grant
Filed:
July 24, 2015
Date of Patent:
May 1, 2018
Assignee:
HJ Science & Technology, Inc.
Inventors:
Hong Jiao, Erik C. Jensen, Homayun Mehrabani, Liran Yosef Haller
Abstract: Reconfigurable microfluidic systems are based on networks of microfluidic cavities connected by hydrophobic microfluidic channels. Each cavity is classified as either a reservoir or a node, and includes a pressure port via which gas pressure may be applied. Sequences of gas pressures, applied to reservoirs and nodes according to a fluid transfer rule, enable fluid to be moved from any reservoir to any other reservoir in a system. Such systems are suitable for automated microwell plate interfaces.
Type:
Grant
Filed:
July 24, 2015
Date of Patent:
May 1, 2018
Assignee:
HJ Science & Technology, Inc.
Inventors:
Hong Jiao, Erik C Jensen, Homayun Mehrabani, Liran Yosef Haller
Abstract: Reconfigurable microfluidic systems are based on networks of microfluidic cavities connected by hydrophobic microfluidic channels. Each cavity is classified as either a reservoir or a node, and includes a pressure port via which gas pressure may be applied. Sequences of gas pressures, applied to reservoirs and nodes according to a fluid transfer rule, enable fluid to be moved from any reservoir to any other reservoir in a system. Systems may be configured with multiple switched interaction regions connected in series for scalable, multiplexed immunoassays. Multiple, switched interaction regions may also be implemented with microvalves.
Type:
Grant
Filed:
July 24, 2015
Date of Patent:
August 15, 2017
Assignee:
HJ Science & Technology, Inc.
Inventors:
Hong Jiao, Erik C Jensen, Homayun Mehrabani, Liran Yosef Haller
Abstract: Reconfigurable microfluidic systems are based on networks of microfluidic cavities connected by hydrophobic microfluidic channels. Each cavity is classified as either a reservoir or a node, and includes a pressure port via which gas pressure may be applied. Sequences of gas pressures, applied to reservoirs and nodes according to a fluid transfer rule, enable fluid to be moved from any reservoir to any other reservoir in a system. Systems may be configured with multiple switched interaction regions connected in series for scalable, multiplexed immunoassays. Multiple, switched interaction regions may also be implemented with microvalves.
Type:
Application
Filed:
July 24, 2015
Publication date:
January 26, 2017
Applicant:
HJ Science & Technology, Inc.
Inventors:
Hong Jiao, Erik C. Jensen, Homayun Mehrabani, Liran Yosef Haller
Abstract: Reconfigurable microfluidic systems are based on networks of microfluidic cavities connected by hydrophobic microfluidic channels. Each cavity is classified as either a reservoir or a node, and includes a pressure port via which gas pressure may be applied. Sequences of gas pressures, applied to reservoirs and nodes according to a fluid transfer rule, enable fluid to be moved from any reservoir to any other reservoir in a system. Such systems are suitable for automated, multi-input, multi-output homogeneous assays.
Type:
Application
Filed:
July 24, 2015
Publication date:
January 26, 2017
Applicant:
HJ Science & Technology, Inc.
Inventors:
Hong Jiao, Erik C. Jensen, Homayun Mehrabani, Liran Yosef Haller
Abstract: Reconfigurable microfluidic systems are based on networks of microfluidic cavities connected by hydrophobic microfluidic channels. Each cavity is classified as either a reservoir or a node, and includes a pressure port via which gas pressure may be applied. Sequences of gas pressures, applied to reservoirs and nodes according to a fluid transfer rule, enable fluid to be moved from any reservoir to any other reservoir in a system. Such systems are suitable for automated microwell plate interfaces.
Type:
Application
Filed:
July 24, 2015
Publication date:
January 26, 2017
Applicant:
HJ SCIENCE & TECHNOLOGY, INC.
Inventors:
Hong Jiao, Erik C Jensen, Homayun Mehrabani, Liran Yosef Haller