Abstract: The present invention relates to alpha 1 multimers and the uses thereof. The invention also relates to methods of producing such multimers, pharmaceutical compositions comprising the same, as well as their uses for treating various diseases including organ/tissue rejection.
Type:
Application
Filed:
June 16, 2010
Publication date:
July 12, 2012
Applicant:
HLA-G TECHNOLOGIES
Inventors:
Laurence Rulleau, Jacques-Francois Martin
Abstract: The present invention relates to novel proteins and pharmaceutical uses thereof The invention more specifically relates to novel proteins comprising the sequence of an HLA-5 antigen fused to the sequence of a b2 microglobulin. The invention also relates to methods of producing such polypeptides, pharmaceutical compositions comprising the same, as well as their uses for treating various diseases including organ/tissue rejection.
Type:
Application
Filed:
November 4, 2009
Publication date:
November 10, 2011
Applicants:
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, HLA-G TECHNOLOGIES
Inventors:
Benoit Favier, Edgardo D. Carosella, Joël Lemaoult
Abstract: The present invention relates to novel proteins and pharmaceutical uses thereof. The invention more specifically relates to novel fusion proteins comprising a domain of an HLA-G antigen fused to an Fc domain of an immunoglobulin. The invention also relates to methods of producing such polypeptides, pharmaceutical compositions comprising the same, as well as their uses for treating various diseases including organ/tissue rejection.
Type:
Application
Filed:
November 4, 2009
Publication date:
November 3, 2011
Applicants:
COMMISSARIAT A L'ENEGRIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, HLA-G TECHNOLOGIES
Inventors:
Benoit Favier, Edgardo D. Carosella, Joël Lemaoult