Abstract: The invention belongs to the field of medicine and chemical industry, and particularly relates to multiple crystal forms of scutellarin aglycone and preparation thereof. The invention also relates to use of said crystal forms of scutellarin aglycone in the manufacture of a medicament for preventing and/or treating a cardiovascular or cerebrovascular disease, rheumatic arthritis or stroke sequelae, etc. The crystal forms of scutellarin aglycone according to the invention have good stability, and can solve the problems concerning poor oral absorption and low bioavailability of scutellarin.
Type:
Grant
Filed:
December 2, 2015
Date of Patent:
January 8, 2019
Assignees:
YUNNAN INSTITUTE OF MATERIA MEDICA, HLK PHARMACEUTICALS CO., LTD.
Inventors:
Zeren Wang, Jun Xu, Minghui Wang, Zhaoyun Zhu, Jingkun Wang, Shuangxi Mei, Wenqiang Sun, Tao Cui