Abstract: A cell culture chamber with a novel hydrodynamic environment, constructed with gas permeable membranes is disclosed. The culture chamber is horizontally rotated, wall movement suspends cells and enhances oxygen mass transfer as cells aggregate and grow into 3-dimensional tissue.
Type:
Grant
Filed:
July 7, 1995
Date of Patent:
June 4, 1996
Assignee:
HMRI/CLMF
Inventors:
Marylou Ingram, Glenn F. Spaulding, James J. G. Craft, Chuen P. Ng, Ramez Saroufeem, Geza B. Techy, Ozkan Yazan