Patents Assigned to Hoechst Aktiengellschaft
  • Patent number: 6482821
    Abstract: Vitronectin receptor antagonists, their preparation and their use The present invention relates to compounds of the formula I, A—B—D—E—F—G   (I) in which A, B, D, E, F and G have the meanings given in the patent claims, to their preparation and to their use as medicaments. The compounds of the invention are used as vitronectin receptor antagonists and as inhibitors of bone resorption.
    Type: Grant
    Filed: February 8, 2001
    Date of Patent: November 19, 2002
    Assignees: Hoechst Aktiengellschaft, Genentech, Inc.
    Inventors: Volkmar Wehner, Hans Ulrich Stilz, Anuschirwan Peyman, Karlheinz Scheunemann, Jean-Marie Ruxer, Denis Carniato, Jean-Michel Lefrancois, Thomas Richard Gadek, Robert McDowell
  • Patent number: 5852197
    Abstract: The invention relates to cyclic diphosphoric esters of the formula ##STR1## with R=methylethylene, 1,3-cyclohexylene, 1,4-cyclo-hexylene or 1,3-phenylene, a process for their preparation and their use as flame retardants.
    Type: Grant
    Filed: July 15, 1996
    Date of Patent: December 22, 1998
    Assignee: Hoechst Aktiengellschaft
    Inventor: Horst Staendeke
  • Patent number: 5424053
    Abstract: The invention relates to a process for the preparation of mixtures of synthetic, crystalline kenyaite and salts which split off oxygen. For this purpose, 1 mol of soda-water glass which has a molar ratio of SiO.sub.2 :Na.sub.2 O=1:(0.25 to 0.5) is mixed with 0.1 to 0.9 mol of a compound which has a pH of less than 10.5 in molar aqueous concentration, as a neutralizing agent. In the presence of kenyaite seed crystals, the reaction mixture is heated at temperatures from 373 to 523 K. in an autoclave for 1 to 10 hours and, after cooling, 0.15 to 1.5 mol of hydrogen peroxide are added per mol of soda-water glass employed. The solid is isolated from the reaction suspension as dry substance.
    Type: Grant
    Filed: February 28, 1994
    Date of Patent: June 13, 1995
    Assignee: Hoechst Aktiengellschaft
    Inventor: Harald Bauer
  • Patent number: 5328969
    Abstract: A very active catalyst system for olefin polymerization comprises a cocatalyst, preferably an aluminoxane, and a metallocene of the formula I ##STR1## in which, preferably, M.sup.1 is Zr or Hf, R.sup.1 and R.sup.2 are alkyl or halogen, R.sup.3 is hydrogen, R.sup.4 to R.sup.6 are alkyl or aryl, --(CR.sup.8 R.sup.9).sub.m --R.sup.7 --(CR.sup.8 R.sup.9).sub.n is a single- or multi-membered chain, in which R.sup.7 can also be a (substituted) hetero atom, and m+n is zero or 1.
    Type: Grant
    Filed: November 24, 1992
    Date of Patent: July 12, 1994
    Assignee: Hoechst Aktiengellschaft
    Inventors: Andreas Winter, Jurgen Rohrmann, Volker Dolle, Frank Kuber
  • Patent number: 4942176
    Abstract: A description is given of a process for the preparation of a compound of the formula I ##STR1## in which R.sup.1, R.sup.2 and R.sup.3 (identical or different) represent H, alkyl having 1-2 carbon atoms and F, Cl, Br or I;R.sup.4 represents H, alkyl having 1-4 carbon atoms, n represents the numbers 2-5, andR.sup.5 represents a radical which can be eliminated under physiological conditions or represents hydrogen, and its physiologically tolerated salts.They are effective remedies for diarrhea.
    Type: Grant
    Filed: May 4, 1989
    Date of Patent: July 17, 1990
    Assignee: Hoechst Aktiengellschaft
    Inventors: Heinrich C. Englert, Max Hropot, Hans-Jochen Lang, Rainer Greger
  • Patent number: 4689416
    Abstract: The reaction for the preparation of 1-oxa-3,8-diaza-4-oxo-spiro[4.5]decane compounds of the formula ##STR1## proceeds more rapidly and more completely if it is performed in the presence of a phase transfer catalyst in an aromatic hydrocarbon which is liquid at room temperature.
    Type: Grant
    Filed: July 8, 1986
    Date of Patent: August 25, 1987
    Assignee: Hoechst Aktiengellschaft
    Inventors: Josef Ertl, Hartmut Wiezer