Abstract: What are disclosed are compounds, useful as intermediates in the preparation of substituted penem compounds, of the formula ##STR1## methods for making such compounds from intermediates of the formula ##STR2## by reaction of the latter with a nucleophilic compound, methods for making such intermediates from compounds of the formula ##STR3## by reaction of the last-mentioned compounds with a tervalent phosphorus compound, and methods for making said last-mentioned compounds by cyclizing compounds of the formula ##STR4## with a tervalent phosphorus compound.
Type:
Grant
Filed:
November 4, 1981
Date of Patent:
October 2, 1984
Assignee:
Hoechst U.K. Limited
Inventors:
Barry C. Ross, Graham Johnson, Michael A. Yeomans