Patents Assigned to HOLOGIC
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Publication number: 20240169958Abstract: The invention includes a method including the steps of obtaining a plurality of images, each of the images in the plurality having at least one corresponding region, generating a merged image, the merged image also having the corresponding region. The step of generating includes selecting an image source from the plurality of images to source image data for the corresponding region in the merged image by comparing attributes of the corresponding regions of the plurality of images to identify the image source having preferred attributes.Type: ApplicationFiled: October 24, 2023Publication date: May 23, 2024Applicant: Hologic, Inc.Inventors: Kevin Kreeger, Andrew P. Smith, Ashwini Kshirsagar, Jun Ge, Xiangwei Zhang, Haili Chui, Christopher Ruth, Yiheng Zhang, Liyang Wei, Jay Stein
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Publication number: 20240164720Abstract: Examples of the present disclosure describe systems and methods for personalized breast imaging. In aspects, a first set of patient attributes may be collected. The first set of patient attributes may relate to, or be used to determine, for example, breast size, breast thickness, and/or three-dimensional (3D) breast shape. The first set of patient attributes may be used to customize image acquisition parameters for the patient. A second set of patient attributes may also be collected. The second set of patient attributes may relate to, or be used to determine, for example, breast elasticity and breast density. The second set of patient attributes may be used to customize breast compression parameters for the patient. The customized image acquisition parameters and breast compression parameters may then be used to perform one or more procedures (e.g., an imaging procedure, a biopsy procedure, etc.) on the patient's breast.Type: ApplicationFiled: December 13, 2023Publication date: May 23, 2024Applicant: Hologic, Inc.Inventors: Biao CHEN, Haili CHUI
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Patent number: 11986170Abstract: A hybrid image based on different tissue specimen images is generated to compensate for blood and other fluids that interfere with imaging. Specimen is deposited into tray with fluid. X-ray and camera imaging devices acquire images of specimen and fluid. X-ray and optical images are processed for generation of hybrid image. Transparency modifications allow for multiple and different images to contribute to depiction of specimen edges or boundaries that would otherwise appear less clear in x-ray image due to interfering fluid. Transparency modifications in hybrid image also provide for sufficiently high transparency in certain optical image portions that would otherwise be opaque so that objects of interest depicted in x-ray image but not optical image are visible.Type: GrantFiled: December 19, 2019Date of Patent: May 21, 2024Assignee: Hologic, Inc.Inventor: Biao Chen
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Publication number: 20240156510Abstract: A system for modulating delivery of radiofrequency (RF) power to tissue, the system including an RF applicator configured for being positioned adjacent to tissue, an RF generator electrically coupled to the RF applicator, and a controller operatively coupled to the RF generator. The controller includes a tissue impedance measurement circuit operatively coupled with the RF applicator and configured for measuring an impedance of tissue disposed adjacent to the RF applicator, and a power modulation module configured to cause RF power to be delivered from the RF generator to the tissue disposed adjacent to the RF applicator so that an impedance of the tissue tracks a target tissue impedance as a function of time.Type: ApplicationFiled: January 18, 2024Publication date: May 16, 2024Applicant: HOLOGIC, INC.Inventors: William Lucas Churchill, Danielle Gline Allen
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Patent number: 11983799Abstract: A method for processing breast tissue image data includes processing image data of a patient's breast tissue to generate a high-dimensional grid depicting one or more high-dimensional objects in the patient's breast tissue; determining a probability or confidence of each of the one or more high-dimensional objects depicted in the high-dimensional grid; and modifying one or more aspects of at least one of the one or more high-dimensional objects based at least in part on its respective determined probability or confidence to thereby generate a lower-dimensional format version of the one or more high-dimensional objects. The method may further include displaying the lower-dimensional format version of the one or more high-dimensional objects in a synthesized image of the patient's breast tissue.Type: GrantFiled: July 22, 2022Date of Patent: May 14, 2024Assignee: Hologic, Inc.Inventors: Haili Chui, Xiaomin Liu, Xiangwei Zhang
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Publication number: 20240148347Abstract: An imaging system includes a gantry and a compression system coupled to the gantry and rotatable relative to the gantry. The compression system includes a compression paddle, a support platform, and an x-ray receptor disposed below the support platform. An x-ray tube head is coupled to the gantry and includes an x-ray source and a light source. The x-ray tube head is independently rotatable relative to the gantry and the compression system. The light source is configured to generate at least a first light type and a different second light type directed towards the support platform. The second light type being mapped to an x-ray field of the x-ray source, and the generated second light type is based on a tilt angle of the x-ray tube head relative to the support platform and a compression force of the compression paddle.Type: ApplicationFiled: September 18, 2023Publication date: May 9, 2024Applicant: Hologic, Inc.Inventor: Adrian HUNSDON
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Patent number: 11977215Abstract: Automated systems and methods for evaluating specimens affixed to substrates, such as slides, an exemplary system including a slide imager configured for acquiring a plurality of micro images of a specimen affixed to an substrate, the specimen including a plurality of objects distributed within a three-dimensional volume, and for generating a whole specimen image of the specimen using the micro images, wherein objects contained in the specimen are depicted substantially in focus in the whole specimen image regardless of a z-depth of the respective objects within the specimen. The whole specimen image is stored on a storage medium for subsequent review by a cytotechnologist using a computer-controlled review station including a display and a user interface, wherein the review station user interface is configured such that the cytotechnologist can review and classify the stored whole specimen images.Type: GrantFiled: October 9, 2019Date of Patent: May 7, 2024Assignee: Hologic, Inc.Inventors: Raymond Jenoski, Sid Mayer, Robert Jennings, Ryan P. Oliva, John A. McCrorey, Michael D. Quick, Sarah Margaret Harrington
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Publication number: 20240138822Abstract: A biopsy device for percutaneous tissue removal includes an elongated housing having an operational axis, a stylet hub slidably mounted in the housing, where the stylet hub is movable relative to the housing between a proximal, armed position, and a distal, fired position, the stylet hub having a stylet strike, a cannula hub slidably mounted in the housing alongside the stylet hub, and a spring-biased arming member. The cannula hub is movable relative to the housing between a proximal, armed position, and a distal, fired position. The arming member is moveably mounted to the housing proximal of the respective stylet and cannula hubs, and configured for manually-actuated movement from a relaxed, extended position to a loaded, compressed position to define a compressive arming stroke. The biopsy device also includes an arming member biasing spring that restores the arming member from the compressed position to the extended position.Type: ApplicationFiled: October 31, 2023Publication date: May 2, 2024Applicant: HOLOGIC, INC.Inventors: Zachary Stephen Swick, Rosario Friedman, Brett Haarala, David Sauvageau, Donna Schulz Torres
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Publication number: 20240138792Abstract: A system for processing breast tissue images includes an image processing computer and a user interface operatively coupled to the image processing computer, wherein the image processing computer is configured to obtain image data of breast tissue, processing the image data to generate a set of reconstructed image slices, the reconstructed image slices collectively depicting the breast tissue, process respective subsets of the reconstructed image slices to generate a set of image slabs, each image slab comprising a synthesized 2D image of a portion of the breast tissue obtained from a respective subset of the set of reconstructed image slices.Type: ApplicationFiled: September 19, 2023Publication date: May 2, 2024Applicant: Hologic, Inc.Inventors: Nikolaos Gkanatsios, Haili Chui, Xiangwei Zhang
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Patent number: 11963820Abstract: A method of generating a visual representation of a complex medical diagnosis includes receiving a first signal corresponding to a measurement of a patient biological condition. A second signal corresponding to a measurement of a patient performance condition is also received. The first and second signals are processed and a visual representation of a diagnostic assessment is generated. The diagnostic assessment is based at least in part on the patient biological condition and the patient performance condition. The visual representation is marked with the measurement of the patient biological condition and the measurement of the patient performance condition.Type: GrantFiled: December 16, 2016Date of Patent: April 23, 2024Assignee: Hologic, Inc.Inventors: Kevin E. Wilson, Thomas L. Kelly
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Patent number: 11957497Abstract: A method for processing breast tissue image data includes processing the image data to generate a set of image slices collectively depicting the patient's breast; for each image slice, applying one or more filters associated with a plurality of multi-level feature modules, each configured to represent and recognize an assigned characteristic or feature of a high-dimensional object; generating at each multi-level feature module a feature map depicting regions of the image slice having the assigned feature; combining the feature maps generated from the plurality of multi-level feature modules into a combined image object map indicating a probability that the high-dimensional object is present at a particular location of the image slice; and creating a 2D synthesized image identifying one or more high-dimensional objects based at least in part on object maps generated for a plurality of image slices.Type: GrantFiled: March 11, 2022Date of Patent: April 16, 2024Assignee: HOLOGIC, INCInventors: Haili Chui, Liyang Wei, Jun Ge, Xiangwei Zhang, Nikolaos Gkanatsios
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Patent number: 11950941Abstract: An x-ray breast imaging system comprising a compression paddle in which the compression paddle comprises a front wall and a bottom wall. The front wall is configured to be adjacent and face a chest wall of a patient during imaging and the bottom wall configured to be adjacent a length of a top of a compressed breast. The bottom wall extends away from the patient's chest wall, wherein the bottom wall comprises a first portion and a second portion such that the second portion is between the front wall and the first portion. The first portion is generally non-coplanar to the second portion, wherein the compression paddle is movable along a craniocaudal axis. The x-ray breast imaging system also comprises a non-rigid jacket releasably secured to the compression paddle, the non-rigid jacket positioned between the compression paddle and the patient.Type: GrantFiled: September 16, 2021Date of Patent: April 9, 2024Assignee: Hologic, Inc.Inventors: Timothy R. Stango, Kenneth F. Defreitas, Ian Shaw, Jay Stein, Lynne Jameson-Meehan, Loren Niklason
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Patent number: 11950948Abstract: Radiographic imaging techniques include the use of an exposure sequence having a plurality of specimen exposure windows. The plurality of specimen exposure windows have a total exposure time period that satisfies a desired exposure time. The plurality of exposure frames resulting from the plurality of specimen exposure windows are summed to form an output frame. The output frame is provided as output.Type: GrantFiled: September 17, 2019Date of Patent: April 9, 2024Assignee: HOLOGIC, INC.Inventors: Cornell Lee Williams, Brad Polischuk
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Publication number: 20240108296Abstract: A breast support platform for an x-ray imaging system includes a housing having a compression plate and a front wall, and a heating system disposed at least partially within the housing. The heating system is configured to heat at least a portion of the compression plate, at least a portion of the front wall, or at least a portion of the compression plate and the front wall. In an example, the heating system includes a transparent conducting film coupled to an inner surface of the housing. In another example, the heating system includes a blower disposed at least partially within the housing, and the blower is configured to channel hot air across an inner surface of the housing.Type: ApplicationFiled: August 8, 2023Publication date: April 4, 2024Applicant: Hologic, Inc.Inventors: Kenneth F. DeFreitas, Tarpit Patel, Alan Rego, Danielle Niremberg, Douglas Myers, Shusheng He
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Patent number: 11944509Abstract: An implantable tissue marker device is provided to be placed in a soft tissue site through a surgical incision. The device can include a bioabsorbable body in the form of a spiral and defining a spheroid shape for the device, the spiral having a longitudinal axis, and turns of the spiral being spaced apart from each other in a direction along the longitudinal axis. A plurality of markers can be disposed on the body, the markers being visualizable by a radiographic imaging device. The turns of the spiral are sufficiently spaced apart to form gaps that allow soft tissue to infiltrate between the turns and to allow flexibility in the device along the longitudinal axis in the manner of a spring.Type: GrantFiled: September 27, 2022Date of Patent: April 2, 2024Assignee: HOLOGIC, INC.Inventors: George D. Hermann, David B. Willis, Michael J. Drews, Gail S. Lebovic, James B. Stubbs
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Patent number: 11944458Abstract: Breast securement devices for imaging systems are provided. The securement device can include a breast tray configured to support a patient's breast. In one example, one or more walls extend from the breast tray to receive the patient's breast. In another example, a pair of arms pivotably extend at least partially over the breast tray to receive the patient's breast therebetween. In still another example, a membrane covers the breast tray and the patient's breast and selectively couples to the breast tray via a suction force. In yet another example, a paddle includes a plurality of flexible fingers that contour to the patient's breast, or includes an array of pins that independently slide within of the paddle and contour to the patient's breast, or includes a bladder having non-Newtonian fluid. Additionally or alternatively, a sling may receive the patient's breast and support the breast from below.Type: GrantFiled: September 20, 2019Date of Patent: April 2, 2024Assignee: Hologic, Inc.Inventor: James Mullally
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Patent number: 11937886Abstract: Disclosed biopsy markers are adapted to serve as localization markers during a surgical procedure. Adaptation includes incorporation of materials detectable under ultrasound during surgery, as well as features for co-registration with image guidance or other real-time imaging technologies during surgery. Such biopsy markers, when used as localization markers, improve patient comfort and reduce challenges in surgical coordination and surgery time. Additional disclosed biopsy markers are adapted to serve as monitoring and/or detection apparatuses, Localization of an implanted marker may be done with ultrasound technology. Ultrasound image data is analyzed to identify the implanted marker. A distance to the marker or a lesion may be determined and displayed. The determined distance may be a distance between the ultrasound probe and the marker or lesion, a distance between the marker or lesion and an incision instrument, and/or a distance between the ultrasound probe and the incision instrument.Type: GrantFiled: November 11, 2021Date of Patent: March 26, 2024Assignee: Hologic, Inc.Inventors: John Laviola, Shawn St. Pierre, Brian Stellmach, Lori Fontaine, Joseph A. Stand, III, Estefania Alvarez, Stephen Grantz, Michelle Dawn Lyman, Shannon Marie Butler, Yuliya Mathis
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Patent number: 11918276Abstract: A system is configured to delivering radiofrequency power to the endometrial lining tissue of a uterine cavity, including modulating the delivered power so that a measured impedance of the endometrial lining tissue tracks a target impedance as a function of time, wherein the target tissue impedance is derived from a function that approximates a preferred endometrial lining tissue ablation impedance curve that is determined based upon a measured impedance of the endometrial lining tissue after RF power has been delivered for a predetermined initial time period.Type: GrantFiled: January 5, 2023Date of Patent: March 5, 2024Assignee: Hologic, Inc.Inventors: William Lucas Churchill, Danielle Gline Allen
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Patent number: 11918389Abstract: Methods, devices, apparatuses and systems are disclosed for performing mammography, such as utilizing tomosynthesis in combination with breast biopsy.Type: GrantFiled: July 23, 2020Date of Patent: March 5, 2024Assignee: Hologic, Inc.Inventors: Kenneth Defreitas, John Laviola, Loren Thomas Niklason, Tao Wu, Joseph Mark, Michael Miller, Jay Stein, Andrew Smith
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Publication number: 20240065614Abstract: Examples of the present disclosure describe systems and methods for the long-term, real-time active monitoring of a wireless implant. In aspects, a wireless biosensor may be implanted in a breast biopsy cavity. The biosensor may detect biochemical parameter data of the breast biopsy cavity and the human body. The biosensor may transmit the detected biochemical parameter data in real-time to a surveillance system wirelessly coupled to the biosensor. The surveillance system may then facilitate the evaluation of the biochemical parameter data. In examples, the evaluation may comprise detecting trends in a tumor's microenvironment, monitoring the progress of a treatment, or adjusting a treatment to tailor a personalized treatment.Type: ApplicationFiled: September 11, 2023Publication date: February 29, 2024Applicant: Hologic, Inc.Inventor: Estefania ALVAREZ