Patents Assigned to Hologic, Inc.
  • Publication number: 20250132016
    Abstract: Systems and methods for generating and using customized hanging protocol for the display of medical images. The methods may include receiving an indication to create a first hanging step of the hanging protocol, displaying a workspace having a plurality of viewports for displaying medical images, and displaying a plurality of building blocks corresponding to different types of medical images. The method may also include receiving a selection of a first building block in the plurality of building blocks, wherein the first building block corresponds to a first type of medical image, and receiving an indication of a location in the workspace for the first building block to be placed. Based on the indication of the location in the workspace for the first building block, one or more of the plurality of viewports is filled with the first building block.
    Type: Application
    Filed: November 4, 2024
    Publication date: April 24, 2025
    Applicant: Hologic, Inc.
    Inventors: Yung-Min CHEN, Edgar Weixiong CHEN, Brian Albert GARFINKEL, Brian Todd MATUSKA, Nikolaos GKANATSIOS, Calvin J. WONG, Herschel Anthony SOLIS, Jessica LUU, Stewart SCHIFFMAN
  • Publication number: 20250127495
    Abstract: A biopsy system driver includes a motor having a rotatable output shaft, a support structure, a drive shaft, an elongate lead screw and a biopsy instrument drive member. The drive shaft is rotatably coupled to the support structure and includes or is otherwise operatively connected to the motor output shaft such that activation of the motor rotates the drive shaft. The elongate lead screw is coupled to the drive shaft such that rotation of the drive shaft rotates the lead screw about an axis of the lead screw. The lead screw is axially translatable relative to the drive shaft and to the support structure. The biopsy instrument drive member is threadably coupled to the lead screw such that rotation of the lead screw causes axial translation of one of the lead screw and biopsy instrument drive member relative to the other one and to the support structure.
    Type: Application
    Filed: September 17, 2024
    Publication date: April 24, 2025
    Applicant: Hologic, Inc.
    Inventors: Joseph A. Stand, III, Kevin M. Thompson, Christian M. Ulm, Arnold Oyola, Fareeha Safir, Daniel Robertson, Thomas Fisk, Peter Wolton
  • Publication number: 20250127465
    Abstract: An imaging system includes a gantry and a compression system coupled to the gantry and rotatable relative to the gantry. The compression system includes a compression paddle, a support platform, and an x-ray receptor disposed below the support platform. An x-ray tube head is coupled to the gantry and includes an x-ray source and a light source. The x-ray tube head is independently rotatable relative to the gantry and the compression system. The light source is configured to generate at least a first light type and a different second light type directed towards the support platform. The second light type being mapped to an x-ray field of the x-ray source, and the generated second light type is based on a tilt angle of the x-ray tube head relative to the support platform and a compression force of the compression paddle.
    Type: Application
    Filed: September 17, 2024
    Publication date: April 24, 2025
    Applicant: Hologic, Inc.
    Inventor: Adrian HUNSDON
  • Publication number: 20250123461
    Abstract: A system and method for acquiring images of objects distributed within a specimen affixed to a surface of a slide, the specimen having an uneven height relative to the slide surface using a camera having an objective lens with an optical axis that forms a non-orthogonal angle with the surface of the slide, the method including acquiring a first plurality of images of a first linear portion of the specimen; evaluating a focus of objects within the linear portion of the specimen captured in the first plurality of images; and acquiring a second plurality of images of the first linear portion or of a second linear portion of the specimen different from the first, wherein a height of the objective lens relative to the slide surface is varied during acquisition of the second plurality of images based on the evaluated focus of the objects captured in the first plurality of images.
    Type: Application
    Filed: December 20, 2024
    Publication date: April 17, 2025
    Applicant: Hologic, Inc.
    Inventors: Barry F. Hunt, Jeffrey D. Struven, Sidney H. Mayer
  • Publication number: 20250114148
    Abstract: Disclosed biopsy markers are adapted to serve as localization markers during a surgical procedure. Adaptation includes incorporation of materials detectable under ultrasound during surgery, as well as features for co-registration with image guidance or other real-time imaging technologies during surgery. Such biopsy markers, when used as localization markers, improve patient comfort and reduce challenges in surgical coordination and surgery time. Additional disclosed biopsy markers are adapted to serve as monitoring and/or detection apparatuses. Localization of an implanted marker may be done with ultrasound technology. Ultrasound image data is analyzed to identify the implanted marker. A distance to the marker or a lesion may be determined and displayed. The determined distance may be a distance between the ultrasound probe and the marker or lesion, a distance between the marker or lesion and an incision instrument, and/or a distance between the ultrasound probe and the incision instrument.
    Type: Application
    Filed: September 24, 2024
    Publication date: April 10, 2025
    Applicant: Hologic, Inc.
    Inventors: John LAVIOLA, Shawn ST. PIERRE, Brian STELLMACH, Lori FONTAINE, Joseph A. STAND, III, Estefania ALVAREZ, Stephen GRANTZ, Michelle Dawn LYMAN, Shannon Marie BUTLER, Yuliya MATHIS
  • Publication number: 20250114055
    Abstract: A method of compressing a breast of a patient with a breast imaging system includes obtaining an x-ray area of the breast of the patient. The x-ray area of the breast is compared to a data set, and a target force is based at least in part on the comparison is identified. A compressive force is applied to the breast, and is based at least in part on the target force. The breast is imaged with the breast imaging system.
    Type: Application
    Filed: September 19, 2024
    Publication date: April 10, 2025
    Applicant: Hologic, Inc.
    Inventors: Alan REGO, Andrew SMITH, David WOLFF, Kenneth F. DEFREITAS
  • Patent number: 12268535
    Abstract: An imaging system includes an x-ray tube head, a support arm, and a compression system coupled to the support arm. The compression system is independently rotatable relative to the x-ray tube head and includes a compression paddle, a support platform, and an x-ray receptor. The imaging system also includes a light assembly coupled to the support arm and disposed above the compression paddle. The light assembly is configured to direct one or more beams of light towards the support platform.
    Type: Grant
    Filed: September 25, 2019
    Date of Patent: April 8, 2025
    Assignee: Hologic, Inc.
    Inventors: Timothy N. Wells, Juliette Buccilli, Alan Rego, Joseph Vartolone
  • Patent number: 12268534
    Abstract: A compression arm device for compressing a breast in an imaging system with a compression paddle. The compression arm device includes a drive for moving the compression paddle towards the breast such that the drive provides a variable resistance during a contact of the compression paddle with the breast.
    Type: Grant
    Filed: January 3, 2024
    Date of Patent: April 8, 2025
    Assignee: Hologic, Inc.
    Inventors: Kenneth Defreitas, Alan Rego
  • Patent number: 12263048
    Abstract: A biopsy site marker configured to expand upon deployment into a biopsy cavity, and visible under several different imaging modalities, comprises a superabsorbent hydrogel component and a radiopaque element. The hydrogel is in a compressed, dehydrated state prior to deployment to facilitate placement of the marker within the biopsy site, and thereafter expands upon deployment in the biopsy site. Such expansion limits migration of the site marker.
    Type: Grant
    Filed: December 4, 2023
    Date of Patent: April 1, 2025
    Assignee: HOLOGIC, INC.
    Inventors: Estefania Alvarez, Adam Kozak, Jaimee Robertson, Stephen Spiegelberg
  • Patent number: 12254586
    Abstract: Examples of the present disclosure describe systems and methods for an auto-focus tool for multimodality image review. In aspects, an image review system may provide for the display of a set of medical images representing one or more imaging modalities. The system may also provide an auto-focus tool that may be used during the review of the set of medical images. After receiving an instruction to activate the auto-focus tool, the system may receive a selection of an ROI in at least one of the images in the set of medical images. The auto-focus tool may identify the location of the ROI within the image and use the identified ROI location to identify a corresponding area or ROI in the remaining set of medical images. The auto-focus tool may orient and display the remaining set of medical images such that the identified area or ROI is prominently displayed.
    Type: Grant
    Filed: September 7, 2022
    Date of Patent: March 18, 2025
    Assignee: Hologic, Inc.
    Inventors: Herschel A. Solis, Calvin J. Wong
  • Publication number: 20250082292
    Abstract: A method for processing breast tissue image data includes obtaining image data of a patient's breast tissue, processing the image data to generate a set of image slices, the image slices collectively depicting the patient's breast tissue; feeding image slices of the set through each of a plurality of object-recognizing modules, each of the object-recognizing modules being configured to recognize a respective type of object that may be present in the image slices; combining objects recognized by the respective object-recognizing modules to generate a synthesized image of the patient's breast tissue; and displaying the synthesized image.
    Type: Application
    Filed: July 18, 2024
    Publication date: March 13, 2025
    Applicant: Hologic, Inc.
    Inventors: Haili CHUI, Liyang WEI, Jun GE, Nikolaos GKANATSIOS
  • Publication number: 20250082312
    Abstract: A tissue removal device includes a housing, an outer tube having a distal portion configured for transcervical insertion into a uterus, an inner tube slidably disposed within the outer tube lumen, a vacuum generation chamber disposed within the housing, a movable piston slidably disposed in the vacuum generation chamber, a collection chamber, a manual actuator moveably coupled to the housing and operatively coupled to the piston, and proximal and distal one-way valves. The outer tube has an outer tube lumen, a tissue in-take opening proximate a distal end thereof, and a proximal end coupled to the housing. The inner tube has an inner tube lumen extending from an open inner tube distal end to an open inner tube proximal end, the open inner tube distal end comprising a cutting edge configured to sever intrauterine tissue extending through the tissue in-take opening in the outer tube.
    Type: Application
    Filed: November 25, 2024
    Publication date: March 13, 2025
    Applicant: HOLOGIC, INC.
    Inventors: Roy H. Sullivan, Jessica Tina Schenck, George Charles Michaels
  • Publication number: 20250072856
    Abstract: An x-ray breast imaging system includes a breast support platform including an x-ray receptor, and an x-ray tube head. The x-ray tube head includes an x-ray source configured to emit an x-ray beam in a direction towards the x-ray receptor, and a collimator. A filter assembly including a plurality of filter slots selectively positionable adjacent to the collimator, and a specimen imaging filter disposed within a slot of the plurality of filter slots. The specimen imaging filter includes at least one aperture defined therein. The specimen imaging filter also blocks a portion of the emitted x-ray beam so that the at least one aperture defines a path of the emitted x-ray beam towards the x-ray receptor.
    Type: Application
    Filed: September 17, 2024
    Publication date: March 6, 2025
    Applicant: Hologic, Inc.
    Inventors: Filip Nikolas BUNDRA, Christine JANSSEN, Zhenxue JING, Tarpit PATEL, Thomas DEYOUNG
  • Patent number: 12239471
    Abstract: Systems and methods for x-ray imaging a patient's breast in combinations of dual-energy, single-energy, mammography and tomosynthesis modes that facilitate screening for and diagnosis of breast abnormalities, particularly breast abnormalities characterized by abnormal vascularity.
    Type: Grant
    Filed: June 17, 2022
    Date of Patent: March 4, 2025
    Assignee: Hologic, Inc.
    Inventors: Andrew P. Smith, Jay A. Stein, Zhenxue Jing, Baorui Ren, Loren Niklason, Christopher Ruth, Ian Shaw
  • Patent number: 12236582
    Abstract: Systems and methods for locating abnormalities within a breast and generating mappings of structures, such as ducts, within the breast. First imaging data may be acquired for a breast from a first imaging modality and second imaging data for the breast from a second imaging modality. The first imaging data is co-registered with the second imaging data, such that the first imaging data and the second imaging data share a common coordinate space. Based on the second imaging data, a plurality of structures within the breast are mapped to generate a mapping of the plurality of structures. From at least one of the first imaging data or the second imaging data, the abnormality in the breast is located. The mapping of the plurality of structures and the located abnormality in the breast may be concurrently displayed. A statistical analysis of the mapping of the breast structures may also be performed.
    Type: Grant
    Filed: September 24, 2019
    Date of Patent: February 25, 2025
    Assignee: Hologic, Inc.
    Inventors: Shawn St. Pierre, Susan Harvey
  • Patent number: 12236597
    Abstract: A method of correlating regions in an image pair including a cranial-caudal image and a medial-lateral-oblique image. Data from a similarity matching model is received by an ensemble model, the data including at least a matched pair of regions and a first confidence level indicator associated with the matched pair of regions. Data from a geo-matching model is received by the ensemble model, the data from the geo-matching model including at least the matched pair of regions and a second confidence level indicator. A joint probability of correlation is determined by the ensemble model based on evaluation of each of the first and second confidence level by the ensemble matching model, wherein the joint probability of correlation provides a probability that the region in each image correlates to the corresponding region in the other image. The joint probability of correlation is provided to an output device.
    Type: Grant
    Filed: May 22, 2024
    Date of Patent: February 25, 2025
    Assignee: Hologic, Inc.
    Inventors: Haili Chui, Ashwini Kshirsagar, Xiangwei Zhang
  • Patent number: 12226222
    Abstract: Examples of the present disclosure describe systems and methods for the long-term, real-time active monitoring of a wireless implant. In aspects, a wireless biosensor may be implanted in a breast biopsy cavity. The biosensor may detect biochemical parameter data of the breast biopsy cavity and the human body. The biosensor may transmit the detected biochemical parameter data in real-time to a surveillance system wirelessly coupled to the biosensor. The surveillance system may then facilitate the evaluation of the biochemical parameter data. In examples, the evaluation may comprise detecting trends in a tumor's microenvironment, monitoring the progress of a treatment, or adjusting a treatment to tailor a personalized treatment.
    Type: Grant
    Filed: September 11, 2023
    Date of Patent: February 18, 2025
    Assignee: Hologic, Inc.
    Inventor: Estefania Alvarez
  • Patent number: 12226233
    Abstract: Examples of the present disclosure describe systems and methods for personalized breast imaging. In aspects, a first set of patient attributes may be collected. The first set of patient attributes may relate to, or be used to determine, for example, breast size, breast thickness, and/or three-dimensional (3D) breast shape. The first set of patient attributes may be used to customize image acquisition parameters for the patient. A second set of patient attributes may also be collected. The second set of patient attributes may relate to, or be used to determine, for example, breast elasticity and breast density. The second set of patient attributes may be used to customize breast compression parameters for the patient. The customized image acquisition parameters and breast compression parameters may then be used to perform one or more procedures (e.g., an imaging procedure, a biopsy procedure, etc.) on the patient's breast.
    Type: Grant
    Filed: December 13, 2023
    Date of Patent: February 18, 2025
    Assignee: Hologic, Inc.
    Inventors: Biao Chen, Haili Chui
  • Patent number: 12226250
    Abstract: Systems and methods for determining body composition by combining dual-energy x-ray (DXA) technology with three-dimensional (3D) optical technology and/or bioimpedance technology. A multi-modality scanning system may include a dual-energy x-ray source and an x-ray detector mounted to opposing sides a c-arm and configured to scan a patient on a optically translucent table. The system may also include one or more 3D optical imaging devices to capture 3D optical images of the patient substantially concurrently with the emission of the dual energy x-rays. A bioimpedance machine may also be included in the multi-modality scanning system. Data based on the dual-energy x-rays may be combined with the data from the 3D optical images and/or the bioimpedance data to generate values of at least three compartments selected from: bone, fat tissue, lean tissue, dehydrated lean tissue, and water.
    Type: Grant
    Filed: March 22, 2018
    Date of Patent: February 18, 2025
    Assignees: Hologic, Inc., The Regents of the University of California
    Inventors: Kevin E. Wilson, John A. Shepherd, Bennett K. Ng, Mark Guetersloh, Chao Huang, Thomas L. Kelly, Wei Wang, Howard Weiss
  • Patent number: D1071196
    Type: Grant
    Filed: November 23, 2022
    Date of Patent: April 15, 2025
    Assignee: HOLOGIC, INC.
    Inventors: Ken DeFreitas, Jaroslaw S. Guz