Patents Assigned to Homodeus, Inc.
  • PROTEIN HOMOLOG DISCOVERY
    Publication number: 20210202041
    Abstract: The present disclosure provides, in some aspects, protein homolog discovery methods for enhanced co-evolution-based protein structure prediction.
    Type: Application
    Filed: December 10, 2020
    Publication date: July 1, 2021
    Applicant: Homodeus, Inc.
    Inventors: Harry Kemble, Spencer Glantz, Jonathan M. Rothberg
  • RECOMBINASE DISCOVERY
    Publication number: 20210174902
    Abstract: The present disclosure provides methods, compositions, kits, and systems for identifying recombinases and cognate site-specific recombinase recognition sites as well as method for using the identified recombinase/recognition site pairs.
    Type: Application
    Filed: December 10, 2020
    Publication date: June 10, 2021
    Applicant: Homodeus, Inc.
    Inventors: Harry Kemble, Spencer Glantz, Jonathan M. Rothberg
  • PROTEIN STRUCTURE PREDICTION
    Publication number: 20210174893
    Abstract: The present disclosure provides, in some aspects, methods for using FRET-based distance measurements to refine and constrain protein structure prediction algorithms.
    Type: Application
    Filed: December 10, 2020
    Publication date: June 10, 2021
    Applicant: Homodeus, Inc.
    Inventors: Benjamin Rosenbluth, Brian Reed, Jonathan M. Rothberg
  • GENERATIVE MACHINE LEARNING MODELS FOR PREDICTING FUNCTIONAL PROTEIN SEQUENCES
    Publication number: 20210174909
    Abstract: The present disclosure provides, in some embodiments, techniques for using generative machine learning models to generate new functional protein sequences based on an input protein structure, such that the new functional protein sequences are structurally similar to the input protein structure but have new and diverse protein sequences. The techniques described herein may be used alone, or in conjunction with structural prediction algorithms and/or to generate diversified gene libraries in directed evolution techniques.
    Type: Application
    Filed: December 10, 2020
    Publication date: June 10, 2021
    Applicant: Homodeus, Inc.
    Inventors: Jonathan M. Rothberg, Zhizhuo Zhang, Spencer Glantz