Abstract: Method for relieving cough using an effective antitussive chemical compound belonging to stemoamide or tuberostemospironine and method for manufacturing pharmaceutical compositions for treating or relieving cough in human and animal subjects which including a stemoamide or tuberostemospironine compound. In addition, the antitussive property of the compounds provides a method for assessing the quality of herbs traditionally used in treating cough by analyzing the content of the effective chemical ingredient, i.e., compounds of stemoamide type and/or tuterostemospironine type. It further provides a method for identifying medicinal herbs which may be used for relieving cough by phytochemical determination of the existence of compounds that are of stemoamide or tuterostemospironine type.
Type:
Grant
Filed:
September 12, 2005
Date of Patent:
January 11, 2011
Assignee:
Hong Kong Jockey Club Institute of Chinese Medicine Limited
Inventors:
Pui-Hay Paul But, Yan-Tong Xu, Pang Chui Shaw, Ren Wang Jiang, Po Ming Hon
Abstract: Three pairs of C-2 epimeric xanthones isolated from Garcinia hanburyi and method for efficiently separating the xanthone compounds into individual epimers, each of which possesses varying biological effects. The compounds are useful for their anticancer effects, particularly because they are shown to be non-substrates of the multidrug-resistance transporter. Some of the epimers have significant inhibitory effects on cytochrome P450 systems. The xanthone compounds of the present invention are gambogic acid, epigambogic acid, isogambogic acid, isoepigambogic acid, 30-hydroxygambogic acid and 30-hydroxyepigambogic acid.
Type:
Application
Filed:
December 21, 2006
Publication date:
June 28, 2007
Applicant:
Hong Kong Jockey Club Institute of Chinese Medicine Limited
Abstract: The present invention relates to the use of Chinese herbs Shu Di Huang, Yin Yang Huo, Shan Zhu Yu, Shan Yao, Gou Qi Zi, and Dan Dou Chi in preparation formulations for the treatment of menopausal syndromes and related symptoms.
Type:
Application
Filed:
August 11, 2005
Publication date:
December 7, 2006
Applicant:
Hong Kong Jockey Club Institute of Chinese Medicine Limited
Inventors:
Yongzheng Hui, Quanzhong Sun, Guoshun Tang, Yuan Wang, Weiyong Wu, Zhen Chen, Lai Leung, Leung Chan, Jun Wang