Patents Assigned to Hormos Medical Ltd.
  • Method for the treatment or prevention of lower urinary tract symptoms
    Patent number: 10780063
    Abstract: This invention concerns a method for treatment or prevention of lower urinary tract symptoms with or without pelvic pain in an individual, said method comprising administering to the individual an effective amount of a selective estrogen receptor modulator, or an isomer, isomer mixture or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: May 8, 2018
    Date of Patent: September 22, 2020
    Assignee: HORMOS MEDICAL LTD.
    Inventors: Risto Santti, Tomi Streng
  • Method for the treatment or prevention of lower urinary tract symptoms
    Patent number: 9993442
    Abstract: This invention concerns a method for treatment or prevention of lower urinary tract symptoms with or without pelvic pain in an individual, said method comprising administering to the individual an effective amount of a selective estrogen receptor modulator, or an isomer, isomer mixture or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: August 21, 2015
    Date of Patent: June 12, 2018
    Assignee: HORMOS MEDICAL LTD.
    Inventors: Risto Santti, Tomi Streng
  • Method for the alleviation of dyspareunia in women
    Patent number: 9566252
    Abstract: This invention relates to a method for inhibition of skin atrophy, or epithelial or mucosal atrophy in women, or to a method for treatment or prevention of symptoms related to said atrophy, said method comprising administering to the woman an effective amount of the compound of formula (I) or a geometric isomer, a stereoisomer, a pharmaceutically acceptable salt, an ester thereof or a metabolite thereof.
    Type: Grant
    Filed: July 15, 2010
    Date of Patent: February 14, 2017
    Assignee: HORMOS MEDICAL LTD.
    Inventors: Kaija Halonen, Lauri Kangas, Michael W. DeGregorio
  • Method for the treatment or prevention of lower urinary tract symptoms
    Patent number: 9114106
    Abstract: This invention concerns a method for treatment or prevention of lower urinary tract symptoms with or without pelvic pain in an individual, said method comprising administering to the individual an effective amount of a selective estrogen receptor modulator, or an isomer, isomer mixture or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: January 15, 2015
    Date of Patent: August 25, 2015
    Assignee: HORMOS MEDICAL LTD.
    Inventors: Risto Santti, Tomi Streng
  • Method for the treatment or prevention of lower urinary tract symptoms
    Patent number: 8962693
    Abstract: This invention concerns a method for treatment or prevention of lower urinary tract symptoms with or without pelvic pain in an individual, said method comprising administering to the individual an effective amount of a selective estrogen receptor modulator, or an isomer, isomer mixture or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: August 19, 2013
    Date of Patent: February 24, 2015
    Assignee: Hormos Medical Ltd.
    Inventors: Risto Santti, Tomi Streng
  • Method for enhancing the bioavalability of ospemifene
    Patent number: 8772353
    Abstract: This invention relates to a method for enhancing the bioavailability of a therapeutically active compound of the formula (I) or a geometric isomer, a stereoisomer, a pharmaceutically acceptable salt, an ester thereof or a metabolite thereof, wherein said compound is administered orally to the individual in connection with the intake of food.
    Type: Grant
    Filed: May 29, 2013
    Date of Patent: July 8, 2014
    Assignee: Hormos Medical Ltd.
    Inventor: Markku Anttila
  • Oral formulations of ospemifene
    Patent number: 8758821
    Abstract: This invention relates to a liquid or semisolid oral drug formulation comprising a therapeutically active compound of the formula (I) or a geometric isomer, a stereoisomer, a pharmaceutically acceptable salt, an ester thereof or a metabolite thereof, in combination with a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: November 6, 2006
    Date of Patent: June 24, 2014
    Assignee: Hormos Medical Ltd.
    Inventors: Veli-Matti Lehtola, Soili Anttila, Esa Anttila, Pirkko Krikku, Pälvi Erkkilä
  • METHODS FOR THE ALLEVIATION OF SEXUAL DYSFUNCTION IN WOMEN
    Publication number: 20140142195
    Abstract: This invention relates to a method for inhibition of skin atrophy, or epithelial or mucosal atrophy in women, or to a method for treatment or prevention of symptoms related to said atrophy, said method comprising administering to the woman an effective amount of the compound of formula (I) or a geometric isomer, a stereoisomer, a pharmaceutically acceptable salt, an ester thereof or a metabolite thereof.
    Type: Application
    Filed: January 24, 2014
    Publication date: May 22, 2014
    Applicants: HORMOS MEDICAL LTD.
    Inventors: Kaija HALONEN, Lauri KANGAS, Michael W. DEGREGORIO
  • METHOD FOR ENHANCING THE BIOAVALABILITY OF OSPEMIFENE
    Publication number: 20130324614
    Abstract: This invention relates to a method for enhancing the bioavailability of a therapeutically active compound of the formula (I) or a geometric isomer, a stereoisomer, a pharmaceutically acceptable salt, an ester thereof or a metabolite thereof, wherein said compound is administered orally to the individual in connection with the intake of food.
    Type: Application
    Filed: May 29, 2013
    Publication date: December 5, 2013
    Applicant: Hormos Medical LTD.
    Inventor: Anttila Markku
  • Method for enhancing the bioavailability of ospemifene
    Patent number: 8470890
    Abstract: This invention relates to a method for enhancing the bioavailability of a therapeutically active compound of the formula (I) or a geometric isomer, a stereoisomer, a pharmaceutically acceptable salt, an ester thereof or a metabolite thereof, wherein said compound is administered orally to the individual in connection with the intake of food.
    Type: Grant
    Filed: July 6, 2012
    Date of Patent: June 25, 2013
    Assignee: Hormos Medical Ltd.
    Inventor: Anttila Markku
  • Method for the preparation of therapeutically valuable triphenylbutene derivatives
    Patent number: 8293947
    Abstract: The present invention concerns a method for the preparation of therapeutically valuable triphenylbutene derivatives, especially ospemifene or fispemifene.
    Type: Grant
    Filed: September 16, 2010
    Date of Patent: October 23, 2012
    Assignee: Hormos Medical Ltd.
    Inventors: Marja Sodervall, Maire Eloranta, Arja Kalapudas
  • Method of treating men suffering from chronic nonbacterial prostatitis with SERM compounds or aromatase inhibitors
    Patent number: 7825107
    Abstract: A method for treatment or prevention of chronic nonbacterial prostatitis in individuals without urethral sphincter dysfunction, comprises administering an effective amount of (i) a selective estrogen receptor modulator (SERM) having estrogen antagonist effect in the prostate, (ii) an aromatase inhibitor, and/or (iii) an antiestrogen.
    Type: Grant
    Filed: May 22, 2007
    Date of Patent: November 2, 2010
    Assignee: Hormos Medical Ltd.
    Inventors: Risto Santti, Tomi Streng, Jenni Bernoulli, Emrah Yatkin
  • Method for the preparation of therapeutically valuable triphenylbutene derivatives
    Patent number: 7812197
    Abstract: The present invention concerns a method for the preparation of therapeutically valuable triphenylbutene derivatives, especially ospemifene or fispemifene.
    Type: Grant
    Filed: February 13, 2008
    Date of Patent: October 12, 2010
    Assignee: Hormos Medical Ltd.
    Inventors: Marja Sodervall, Maire Eloranta, Arja Kalapudas
  • Methods for the preparation of fispemifene from ospemifene
    Patent number: 7504530
    Abstract: The present invention concerns a method for preparation of fispemifene by use of ospemifene as a starting material.
    Type: Grant
    Filed: February 13, 2008
    Date of Patent: March 17, 2009
    Assignee: Hormos Medical Ltd.
    Inventors: Marja Sodervall, Maire Eloranta, Arja Kalapudas, Brian Kearton, Michael McKenzie
  • Method for treating cryptorchidism
    Patent number: 7345073
    Abstract: The present invention relates to a method and pharmaceutical composition for the treatment of male individuals suffering from cryptorchidism comprising administering to said individuals an effective amount of an aromatase inhibitor, preferably finrozole.
    Type: Grant
    Filed: October 7, 2005
    Date of Patent: March 18, 2008
    Assignee: Hormos Medical Ltd.
    Inventors: Tomi Streng, Sari Mäkelä, Risto Santti, Matti Poutanen, Xiangdong Li
  • METHOD OF TREATING MEN SUFFERING FROM CHRONIC NONBACTERIAL PROSTATITIS WITH SERM COMPOUNDS OR AROMATASE INHIBITORS
    Publication number: 20080021111
    Abstract: A method for treatment or prevention of chronic nonbacterial prostatitis in individuals without urethral sphincter dysfunction, comprises administering an effective amount of (i) a selective estrogen receptor modulator (SERM) having estrogen antagonist effect in the prostate, (ii) an aromatase inhibitor, and/or (iii) an antiestrogen.
    Type: Application
    Filed: May 22, 2007
    Publication date: January 24, 2008
    Applicant: Hormos Medical Ltd.
    Inventors: Risto Santti, Tomi Streng, Jenni Bernoulli, Emrah Yatkin
  • Formulations of fispemifene
    Publication number: 20070104743
    Abstract: This invention relates to a liquid or semisolid oral drug formulation comprising a therapeutically active compound of the formula (I) or a geometric isomer, a stereoisomer, a mixture of isomers, a pharmaceutically acceptable salt, an ester thereof or a metabolite thereof, in combination with a pharmaceutically acceptable carrier.
    Type: Application
    Filed: November 9, 2006
    Publication date: May 10, 2007
    Applicant: HORMOS MEDICAL LTD.
    Inventors: Veli-Matti Lehtola, Kaija Halonen
  • Novel oral formulations of ospemifene
    Publication number: 20070104742
    Abstract: This invention relates to a liquid or semisolid oral drug formulation comprising a therapeutically active compound of the formula (I) or a geometric isomer, a stereoisomer, a pharmaceutically acceptable salt, an ester thereof or a metabolite thereof, in combination with a pharmaceutically acceptable carrier.
    Type: Application
    Filed: November 6, 2006
    Publication date: May 10, 2007
    Applicant: HORMOS MEDICAL LTD.
    Inventors: Veli-Matti Lehtola, Kaija Halonen