Patents Assigned to HOSPIRA AUSTRALIA PTY LTD.
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Publication number: 20210275500Abstract: Concentrated liquid pharmaceutical compositions comprising a) a pharmaceutically effective amount of bendamustine or a pharmaceutically acceptable salt thereof, b) a non-aqueous solvent, and c) at least about 2% water, suitable, after dilution, for administration to a mammal by injection are provided. The concentrated liquid pharmaceutical compositions can comprise a non-aqueous solvent comprising at least one organic polymeric compound solvent and at least one organic small molecule solvent. Methods of treating a cancer in a mammal in need of such treatment comprising administering to the mammal an effective amount of a concentrated liquid bendamustine pharmaceutical composition of the invention are also provided.Type: ApplicationFiled: August 14, 2019Publication date: September 9, 2021Applicant: HOSPIRA AUSTRALIA PTY LTDInventors: Andrew Malcolm Knill, Noel Norris
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Publication number: 20200237858Abstract: Lyophilized daptomycin formulations having improved reconstitution times are provided. The lyophilized daptomycin formulations include an additive, which can be a pharmaceutically acceptable antioxidant, a pharmaceutically acceptable organic acid or a pharmaceutically acceptable salt thereof, a pharmaceutically acceptable glucose derivative or a pharmaceutically acceptable salt thereof, or a combination thereof. Also provided are methods of methods of preparing the lyophilized daptomycin formulations, and methods of treating bacterial infections and treating or preventing biofilms by using the lyophilized daptomycin formulations.Type: ApplicationFiled: April 15, 2020Publication date: July 30, 2020Applicant: Hospira Australia Pty LtdInventors: Jim Alexiou, Andrew Malcolm Knill, Noel Norris, Darryl Whittaker
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Patent number: 10364053Abstract: Embodiments generally relate to vial preparation methods and to vials prepared by such methods. Some embodiments relate to use of an apparatus, such as a lyophilization apparatus, to perform the methods.Type: GrantFiled: August 5, 2011Date of Patent: July 30, 2019Assignee: Hospira Australia Pty LtdInventors: Emma J. Wensley, Andrew Malcolm Knill, John Frederic Suendermann
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Patent number: 10357535Abstract: Lyophilized daptomycin formulations having improved reconstitution times are provided. The lyophilized daptomycin formulations include an additive, which can be a pharmaceutically acceptable antioxidant, a pharmaceutically acceptable organic acid or a pharmaceutically acceptable salt thereof, a pharmaceutically acceptable glucose derivative or a pharmaceutically acceptable salt thereof, or a combination thereof. Also provided are methods of methods of preparing the lyophilized daptomycin formulations, and methods of treating bacterial infections and treating or preventing biofilms by using the lyophilized daptomycin formulations.Type: GrantFiled: February 23, 2018Date of Patent: July 23, 2019Assignee: Hospira Australia Pty LtdInventors: Jim Alexiou, Andrew Malcolm Knill, Noel Norris, Darryl Whittaker
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Publication number: 20180177843Abstract: Lyophilized daptomycin formulations having improved reconstitution times are provided. The lyophilized daptomycin formulations include an additive, which can be a pharmaceutically acceptable antioxidant, a pharmaceutically acceptable organic acid or a pharmaceutically acceptable salt thereof, a pharmaceutically acceptable glucose derivative or a pharmaceutically acceptable salt thereof, or a combination thereof. Also provided are methods of methods of preparing the lyophilized daptomycin formulations, and methods of treating bacterial infections and treating or preventing biofilms by using the lyophilized daptomycin formulations.Type: ApplicationFiled: February 23, 2018Publication date: June 28, 2018Applicant: HOSPIRA AUSTRALIA PTY LTDInventors: Jim Alexiou, Andrew Malcolm Knill, Noel Norris, Darryl Whittaker
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Publication number: 20170216396Abstract: Lyophilized daptomycin formulations having improved reconstitution times are provided. The lyophilized daptomycin formulations include an additive, which can be a pharmaceutically acceptable antioxidant, a pharmaceutically acceptable organic acid or a pharmaceutically acceptable salt thereof, a pharmaceutically acceptable glucose derivative or a pharmaceutically acceptable salt thereof, or a combination thereof. Also provided are methods of methods of preparing the lyophilized daptomycin formulations, and methods of treating bacterial infections and treating or preventing biofilms by using the lyophilized daptomycin formulations.Type: ApplicationFiled: April 20, 2017Publication date: August 3, 2017Applicant: HOSPIRA AUSTRALIA PTY LTD.Inventors: Jim Alexiou, Andrew Malcolm Knill, Noel Norris, Darryl Whittaker
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Patent number: 9655946Abstract: Lyophilized daptomycin formulations having improved reconstitution times are provided. The lyophilized daptomycin formulations include an additive, which can be a pharmaceutically acceptable antioxidant, a pharmaceutically acceptable organic acid or a pharmaceutically acceptable salt thereof, a pharmaceutically acceptable glucose derivative or a pharmaceutically acceptable salt thereof, or a combination thereof. Also provided are methods of methods of preparing the lyophilized daptomycin formulations, and methods of treating bacterial infections and treating or preventing biofilms by using the lyophilized daptomycin formulations.Type: GrantFiled: September 11, 2013Date of Patent: May 23, 2017Assignee: HOSPIRA AUSTRALIA PTY LTD.Inventors: Jim Alexiou, Andrew Knill, Noel Norris, Darryl Whittaker
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Publication number: 20150313958Abstract: Lyophilized daptomycin formulations having improved reconstitution times are provided. The lyophilized daptomycin formulations include an additive, which can be a pharmaceutically acceptable antioxidant, a pharmaceutically acceptable organic acid or a pharmaceutically acceptable salt thereof, a pharmaceutically acceptable glucose derivative or a pharmaceutically acceptable salt thereof, or a combination thereof. Also provided are methods of methods of preparing the lyophilized daptomycin formulations, and methods of treating bacterial infections and treating or preventing biofilms by using the lyophilized daptomycin formulations.Type: ApplicationFiled: September 11, 2013Publication date: November 5, 2015Applicant: HOSPIRA AUSTRALIA PTY LTD.Inventors: Jim Alexiou, Andrew Knill, Noel Norris, Darryl Whittaker
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Publication number: 20110152360Abstract: There is provided a liquid pharmaceutical formulation for parenteral administration comprising: docetaxel or a pharmaceutically acceptable salt thereof; one or more glycols; and a pharmaceutically acceptable nonaqueous solvent system; wherein the formulation has a pH meter reading in the range of from 2.5 to 7.Type: ApplicationFiled: March 2, 2011Publication date: June 23, 2011Applicant: HOSPIRA AUSTRALIA PTY LTD.Inventors: Aikun Julie Liu, Allan Harvey Spencer, Andrew Malcolm Knill, Daniel David Ash