Abstract: The present invention provides a betaine compound for use in the prevention of obesity, excessive fat accumulation and/or metabolic disorders associated with either of the foregoing in a subject, wherein the prevention comprises administering the betaine compound directly to the subject during infancy or, alternatively, to the subject's mother during breast-feeding. Also provided are compositions comprising an effective amount of betaine compound together with one or more pharmaceutically or edible acceptable excipients and/or carriers for this use.

Abstract: The present invention provides a betaine compound for use in the prevention of obesity, excessive fat accumulation and/or metabolic disorders associated with either of the foregoing in a subject, wherein the prevention comprises administering the betaine compound directly to the subject during infancy or, alternatively, to the subject's mother during breast-feeding. Also provided are compositions comprising an effective amount of betaine compound together with one or more pharmaceutically or edible acceptable excipients and/or carriers for this use.

Abstract: The present invention relates to a method and composition for use in treating a condition that benefits from the reduction of hepatic and/or visceral fat, such as polycystic ovary syndrome in adolescent girls or women of childbearing age, involving the use of spironolactone, pioglitazone and metformin.

Abstract: It relates to a nonwoven fabric membrane for topical use on the skin, which comprises polymeric nanofibres and an active agent in an amount from 25 to 80% by weight with respect to the total weight of the nonwoven fabric membrane, wherein the active agent is soluble in a suitable biocompatible solvent system, and wherein the membrane is capable of releasing the active agent immediately when the membrane is contacted with an appropriate amount of the suitable solvent biocompatible system in which the active agent is completely solubilised. It also relates to a process for the preparation of the nonwoven fabric membrane, to a cosmetic or sanitary product and a kit comprising them and to their therapeutic and cosmetic uses.

Abstract: The invention defines a nonwoven membrane for the controlled and sustained release of a therapeutic or cosmetic active agent in the area of the body to be treated. This nonwoven membrane comprises one single type of biocompatible electrospun nanofibers and microparticles of at least one therapeutic or cosmetic active agent which are entangled between the nanofibers, the active agent having a low water solubility.

Abstract: The present invention relates to the field of pediatric or childhood tumor therapy. More specifically, the invention relates to the use of the allosteric activator of the calcium sensor receptor, cinacalcet, for the preparation of a pharmaceutical product for the treatment of neuroblastic tumors, particularly for the treatment of neuroblastomas, ganglioneuroblastomas and ganglioneuromas.

Abstract: The eye movement sensor comprises a helmet (1) adjustable to the head of a patient who is undergoing an ophthalmologic examination, in a unit with seat (10) and projection screen (11) of light spots in front, the same helmet (1) incorporating a front light projector (2) which emits a light spot towards the screen (11), as well as means of image recording of each one of the eyes, which records their movements captured from an angle which permits viewing the eye in all its positions. Said means of recording preferably consists of a video camera (6) disposed below the projector (2) of the helmet (1), focussing a pair of mirrors (7), incorporated on different sides of the lower part of the helmet (1) downward, under each eye respectively, to capture the specular reflection of its movements; or instead, two cameras (5) under each eye.

Abstract: The eye movement sensor comprises a helmet (1) adjustable to the head of a patient who is undergoing an ophthalmologic examination, in a unit with seat (10) and projection screen (11) of light spots in front, the same helmet (1) incorporating a front light projector (2) which emits a light spot towards the screen (11), as well as means of image recording of each one of the eyes, which records their movements captured from an angle which permits viewing the eye in all its positions. Said means of recording preferably consists of a video camera (6) disposed below the projector (2) of the helmet (1), focussing a pair of mirrors (7), incorporated on different sides of the lower part of the helmet (1) downward, under each eye respectively, to capture the specular reflection of its movements; or instead, two cameras (5) under each eye.