Patents Assigned to Huanggang Normal University
  • PREPARATION OF BLACK TEA EXTRACT WITH HIGH THEAFLAVIN CONTENT AND USE THEREOF
    Publication number: 20240148817
    Abstract: Disclosed is a method of preparing black tea extract with high theaflavin content, which utilizes an enzyme solution prepared by extracting polyphenol oxidase and laccase from bergamot yam (Dioscorea opposita foshou) or Chinese yam (Dioscoreae Rhizoma). Also disclosed is a method of treating liver fibrosis or kidney injury or atherosclerosis in a subject.
    Type: Application
    Filed: November 6, 2022
    Publication date: May 9, 2024
    Applicant: Huanggang Normal University
    Inventors: Shiming Li, Weixin Wang, Peng Wu, Ting Hu, Junfeng Shen, Jianfeng Zhan
  • Preparation of a composition containing stilbene glycoside
    Patent number: 10905703
    Abstract: Disclosed is a method of processing Polygonum multiflorum, the method contains preparing a root extract solution and placing the solution under UV light for 1 to 24 hours. Also disclosed is a composition prepared from the method that can be for use in the prevention, treatment, and management of diabetes in human and animal subjects.
    Type: Grant
    Filed: March 10, 2019
    Date of Patent: February 2, 2021
    Assignee: Huanggang Normal University
    Inventor: Shiming Li
  • Method for treating melanoma
    Patent number: 10682332
    Abstract: Disclosed is a method of inhibiting growth of a melanoma cancer cell. The method includes contacting the melanoma cancer cell with an effective amount of a composition and the composition contains polymethoxyflavone. The polymethoxyflavone can be applied in an amount of 0.1 ?mol/L-1000 ?mol/L. A method of treating a subject having melanoma with the above discussed composition is also included.
    Type: Grant
    Filed: August 11, 2017
    Date of Patent: June 16, 2020
    Assignee: Huanggang Normal University
    Inventors: Shiming Li, Tao Long, Guliang Yang, Xiaojian Lv, Yin Xu, Ting Zhang
  • METHOD FOR TREATING DIABETES
    Publication number: 20200093768
    Abstract: Disclosed is a method of treating diabetes. The method includes administering an effective amount of a pharmaceutical composition to a subject in need thereof and the pharmaceutical composition contains ibuprofen. The ibuprofen can be administered at a dosage of 1-300 mg/kg per day and the pharmaceutical composition is administered for at least 30 days.
    Type: Application
    Filed: September 23, 2018
    Publication date: March 26, 2020
    Applicant: Huanggang Normal University
    Inventors: Shiming Li, Alexander Michael Gosslau, Emmanuel Selvanayagam Zachariah
  • Composition containing stilbene glycoside and preparation and uses thereof for treating diabetes
    Patent number: 10272127
    Abstract: Disclosed is a composition for use in the prevention, treatment, and management of diabetes in human and animal subjects that contains 2,3,5,4-tetrahydroxystilbene 2-O-b-glucopyranoside collected from one or more plants selected from the group consisting of Fallopia genera of plants.
    Type: Grant
    Filed: December 4, 2015
    Date of Patent: April 30, 2019
    Assignee: Huanggang Normal University
    Inventors: Shiming Li, Wenping Tang
  • Combination therapy for treating cancer
    Patent number: 9763910
    Abstract: Disclosed is a method of treating a subject having non-small cell lung cancer. The method includes administering to the subject a therapeutically effective amount of a composition and the composition contains 5-demethylnobiletin and docetaxel. Compared with the use of docetaxel alone, the method of combining 5-demethylnobiletin and docetaxel had a 4.4 fold increase in inhibiting the growth of human lung cancer cells, and had a 3.05 fold increase in inhibiting tumor growth in human lung cancer cell-engrafted nude mice.
    Type: Grant
    Filed: December 31, 2016
    Date of Patent: September 19, 2017
    Assignee: Huanggang Normal University
    Inventor: Shiming Li