Patents Assigned to Hubei Ruihaoanke Pharmaceutical Technology Development Co., Ltd.
  • CRYSTAL OF POLYMYXIN B1 SULFATE, POLYMYXIN B2 SULFATE OR THEIR MIXTURE AND PREPARATION METHOD THEREOF
    Publication number: 20210283213
    Abstract: The present invention provides an anhydrous crystal of polymyxin B1 sulfate, polymyxin B2 sulfate or a mixture thereof and a preparation method thereof. The preparation method comprises using an organic solvent to precipitate a solid from a saturated solution of polymyxin B1 sulfate, polymyxin B2 sulfate or a mixture thereof, drying it under vacuum to obtain an anhydrous crystal of polymyxin B1 sulfate, polymyxin B2 sulfate or a mixture thereof.
    Type: Application
    Filed: August 19, 2016
    Publication date: September 16, 2021
    Applicant: Hubei Ruihaoanke Pharmaceutical Technology Development Co., Ltd.
    Inventors: Xiaobing Li, Fen Luo, Zengxia Wang, Yanwei Xu, Changhong Li
  • POLYMYXIN B SULFATE CRYSTAL AND PREPARATION METHOD THEREOF
    Publication number: 20190256557
    Abstract: The present invention provides a polymyxin B sulfate crystal and a preparation method thereof. Said method comprises the following steps of: adsorbing a polymyxin B fermentation liquid with a resin, and adding sulfuric acid or acidic ethanol for desorbing; concentrating to obtain a saturated solution of polymyxin B sulfate; and using an organic solvent to precipitate a crystal from the saturated solution, filtering and drying to obtain the polymyxin B sulfate crystal.
    Type: Application
    Filed: August 19, 2016
    Publication date: August 22, 2019
    Applicant: Hubei Ruihaoanke Pharmaceutical Technology Development Co., Ltd.
    Inventors: Zengxia Wang, Xiaobing Li, Fen Luo, Changhong Li, Yanwei Xu, Long Chen