Abstract: A transgenic animal having a genome including a humanized immunoglobulin locus for securing the diversity of an antibody repertoire and a method of producing the same are disclosed. The transgenic non-human animal has two alleles of a humanized immunoglobulin gene, wherein the two alleles are hetero-alleles.
Type:
Application
Filed:
October 16, 2020
Publication date:
December 30, 2021
Applicant:
Humab Co., Ltd
Inventors:
Chang Kyu OH, Kyoung Seok OH, Soon Ik PARK