Patents Assigned to Humacyte
  • Tissue-engineered constructs
    Patent number: 9556414
    Abstract: The present invention provides constructs including a tubular biodegradable polyglycolic acid scaffold, wherein the scaffold may be coated with extracellular matrix proteins and substantially acellular. The constructs can be utilized as an arteriovenous graft, a coronary graft, a peripheral artery bypass conduit, or a urinary conduit. The present invention also provides methods of producing such constructs.
    Type: Grant
    Filed: January 6, 2012
    Date of Patent: January 31, 2017
    Assignee: HUMACYTE
    Inventors: Shannon L. M. Dahl, Laura E. Niklason, Juliana Blum, Justin T. Strader, William E. Tente, Heather L. Prichard, Joseph J. Lundquist
  • TISSUED-ENGINEERED CONSTRUCTS
    Publication number: 20130345824
    Abstract: The present invention provides constructs including a tubular biodegradable polyglycolic acid scaffold, wherein the scaffold may be coated with extracellular matrix proteins and substantially acellular. The constructs can be utilized as an arteriovenous graft, a coronary graft, a peripheral artery bypass conduit, or a urinary conduit. The present invention also provides methods of producing such constructs.
    Type: Application
    Filed: January 6, 2012
    Publication date: December 26, 2013
    Applicant: HUMACYTE
    Inventors: Shannon L.M. Dahl, Laura E. Niklason, Juliana Blum, Justin T. Strader, William E. Tente, Heather L. Prichard, Joseph Lundquist
  • Tissue-Engineered Constructs
    Publication number: 20130013083
    Abstract: Constructs including a tubular biodegradable polyglycolic acid scaffold may be coated with extracellular matrix proteins and are substantially acellular. The constructs can be utilized as an arteriovenous graft, a coronary graft, an arterial graft, a venous graft, a duct graft, a skin graft, or a urinary graft or conduit.
    Type: Application
    Filed: July 5, 2012
    Publication date: January 10, 2013
    Applicant: HUMACYTE
    Inventors: Juliana L. BLUM, Shannon L.M. DAHL, Laura E. NIKLASON, Justin T. STRADER, William E. TENTE, Heather L. PRITCHARD, Joseph J. LUNDQUIST
  • METHOD FOR ENDOTHELIAL CELL EXTRACTION FROM ADISPOSE TISSUES
    Publication number: 20090319033
    Abstract: Adipose tissue has proven to serve as an abundant, accessible, and rich source of endothelial or vascular endothelial cells suitable for tissue engineering. We describe a detailed method for the isolation and purification of endothelial cells using purified enzymes and antibody-based selection. The cells can be obtained from liposuction procedures and used in vascular grafts.
    Type: Application
    Filed: March 7, 2007
    Publication date: December 24, 2009
    Applicant: Humacyte
    Inventors: Laura E Niklason, Yuling Li