Abstract: The cream formulation of the present invention is a topical cream made with antimycotic (amphotericin B) and a mixture of excipients where the water present in the formulation smoothes inflamed tissue. The cream has a particular application for the treatment of cutaneous leishmaniasis and mucosal leishmaniasis in humans and animals. The topical application avoids the risks of toxicity and the gastrointestinal hassles of pills treatments. It has greater acceptability from patient and does not require of valuations before, during or after treatment to check toxicity levels of the liver, kidney and heart.
Type:
Grant
Filed:
July 26, 2013
Date of Patent:
October 31, 2017
Assignees:
HUMAX PHARMACEUTICAL S.A., UNIVERSIDAD DE ANTIOQUIA
Inventors:
Ivan Dario Velez-Bernal, Sara Maria Robledo-Restrepo, Martha Beatriz Robledo-Restrepo, Alba Lucia Ceballos-Maya, Newar Andres Giraldo-Alzate, Alvaro Gomez-Zuluaga, Juan Jose Zuluaga-Rivera