Patents Assigned to HUMEDICS GMBH
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Patent number: 10862267Abstract: A method for controlling the emission frequency of a laser comprises: recording a first spectrum by passing a laser light emitted by the laser through a sample onto a detector, the detector being connected to a multichannel analyzer which assigns pulses detected by the detector to a channel; determining a first channel to which the maximum of a first signal in the first spectrum has been assigned; determining a second channel to which the maximum of a second signal in the first spectrum has been assigned; recording a second spectrum in analog fashion like the first spectrum; determining whether the maximum of the first signal in the second spectrum has been assigned to the first channel and whether the maximum of the second signal in the second spectrum has been assigned to the second channel; adjusting the operating temperature of the laser in the event of deviations determined in the previous step.Type: GrantFiled: May 19, 2017Date of Patent: December 8, 2020Assignee: HUMEDICS GMBHInventors: Axel Luchterhand, Alexander Helmke, Tom Rubin, Karsten Heyne
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Publication number: 20190305514Abstract: A method for controlling the emission frequency of a laser comprises: recording a first spectrum by passing a laser light emitted by the laser through a sample onto a detector, the detector being connected to a multichannel analyzer which assigns pulses detected by the detector to a channel; determining a first channel to which the maximum of a first signal in the first spectrum has been assigned; determining a second channel to which the maximum of a second signal in the first spectrum has been assigned; recording a second spectrum in analog fashion like the first spectrum; determining whether the maximum of the first signal in the second spectrum has been assigned to the first channel and whether the maximum of the second signal in the second spectrum has been assigned to the second channel; adjusting the operating temperature of the laser in the event of deviations determined in the previous step.Type: ApplicationFiled: May 19, 2017Publication date: October 3, 2019Applicant: Humedics GmbHInventors: Axel LUCHTERHAND, Alexander HELMKE, Tom RUBIN, Karsten HEYNE
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Publication number: 20170052069Abstract: A method for determining the temperature of an infrared-active gas by means of infrared spectroscopy is provided. The method comprising: radiating infrared light in a spectral range of 700 cm?1 to 5000 cm?1 originating from an infrared light source onto the gas; obtaining a first absorption-related parameter originating from measuring a first infrared absorption band of the gas, wherein the first infrared absorption band is a hot band being caused by thermal population of at least one vibrational mode of the gas; obtaining a second absorption-related parameter originating from measuring a second infrared absorption band of the gas, and calculating a ratio between the first absorption-related parameter and the second absorption-related parameter. The method is characterized in that the ratio is used to determine the temperature of the gas, wherein the ratio has a relative change of at least 0.5% per Kelvin temperature difference of the gas.Type: ApplicationFiled: April 28, 2015Publication date: February 23, 2017Applicant: HUMEDICS GMBHInventors: Tom RUBIN, Karsten HEYNE
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Patent number: 9560989Abstract: A method for determining the metabolic capacity of an enzyme includes time-resolved determination of the concentration of a product in exhaled air. The product is created by metabolism of a substrate, previously administered to an individual, by an enzyme of the individual. The product concentration is determined until the maximum product concentration in the exhaled air is reached. A model function is fitted to measured values of the product concentration, obtained by the time-resolved determination of the product concentration between start and end times. The metabolic capacity of the enzyme is determined based on parameters of the model function. Determining the metabolic capacity of the enzyme takes place based on at least two parameters of the model function, wherein the maximum value and time constant of the model function are not selected as parameters at the same time, and the start and/or end times are not selected as parameters.Type: GrantFiled: April 13, 2012Date of Patent: February 7, 2017Assignee: HUMEDICS GMBHInventors: Karsten Heyne, Martin Stockmann, Tom Rubin
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Patent number: 9541497Abstract: A measurement device and a method for analyzing a sample gas by infrared absorption spectroscopy are described. The measurement device comprises a narrowband laser having a line width of less than 0.2 cm?1 and being smaller than a width of an infrared absorption line to be measured of a sample gas. The measurement device is suited and can be arranged to measure the respiratory gas of a human or animal as sample gas, wherein the respiratory gas exchanges in the measurement chamber only by the respiration of the human or animal, and the respiratory resistance of the measurement device is less than 60 mbar.Type: GrantFiled: December 21, 2010Date of Patent: January 10, 2017Assignee: HUMEDICS GMBHInventors: Karsten Heyne, Tom Rubin
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Publication number: 20140107516Abstract: A method for determining the metabolic capacity of an enzyme includes time-resolved determination of the concentration of a product in exhaled air. The product is created by metabolism of a substrate, previously administered to an individual, by an enzyme of the individual. The product concentration is determined until the maximum product concentration in the exhaled air is reached. A model function is fitted to measured values of the product concentration, obtained by the time-resolved determination of the product concentration between start and end times. The metabolic capacity of the enzyme is determined based on parameters of the model function. Determining the metabolic capacity of the enzyme takes place based on at least two parameters of the model function, wherein the maximum value and time constant of the model function are not selected as parameters at the same time, and the start and/or end times are not selected as parameters.Type: ApplicationFiled: April 13, 2012Publication date: April 17, 2014Applicant: HUMEDICS GMBHInventors: Karsten Heyne, Martin Stockmann, Tom Rubin
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Publication number: 20110313677Abstract: A method for determining the liver performance of a living organism, in particular a human, comprising administering at least one 13C labelled substrate, which is converted by the liver by releasing at least one 13C labelled metabolization product, and determining the amount of the at least one 13C labelled metabolization product in the exhalation air over a definite time interval by the means of at least one measuring device with at least one evaluation unit is disclosed. Using this method, it is possible to describe the measured initial increase of the amount of the at least one 13C labelled metabolization product in the exhalation air using a differential equation of first order and to determine a value Amax (DOBmax) and a time constant tau of the increase of the amount of 13C labelled metabolization product from the solution of the differential equation of first order.Type: ApplicationFiled: December 21, 2010Publication date: December 22, 2011Applicant: HUMEDICS GMBHInventor: Karsten Heyne
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Publication number: 20110270113Abstract: A measurement device and a method for analyzing a sample gas by infrared absorption spectroscopy are described. The measurement device comprises: a measurement chamber with the sample gas to be analyzed, a laser being arranged in relation to the measurement chamber such that light being emitted from the laser radiates through the measurement chamber, a detection device detecting the light being emitted from the laser and radiated through the measurement chamber, and an evaluation unit evaluating signals generated by the detection device regarding a light absorption occurred in the measurement chamber.Type: ApplicationFiled: December 21, 2010Publication date: November 3, 2011Applicant: HUMEDICS GMBHInventors: Karsten Heyne, Tom Rubin
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Patent number: D689603Type: GrantFiled: October 4, 2011Date of Patent: September 10, 2013Assignee: Humedics GmbHInventor: Martin Stockmann
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Patent number: D779651Type: GrantFiled: August 4, 2014Date of Patent: February 21, 2017Assignee: HUMEDICS GMBHInventors: Axel Luchterhand, Alexander Helmke