Abstract: Methods for treating or preventing a cancer in a subject are disclosed, wherein the cancer comprises cells having a mutation resulting in increased expression of a ligand for HER3, wherein the method comprises administering a therapeutically or prophylactically effective amount of an antigen-binding molecule which is capable of binding to HER3 to the subject.
Abstract: Methods for treating or preventing a cancer in a subject are disclosed, wherein the cancer comprises cells having a mutation resulting in increased expression of a ligand for HER3, wherein the method comprises administering a therapeutically or prophylactically effective amount of an antigen-binding molecule which is capable of binding to HER3 to the subject.
Type:
Grant
Filed:
January 20, 2021
Date of Patent:
December 28, 2021
Assignee:
Hummingbird Bioscience Holdings Limited
Inventors:
Jerome Douglas Boyd-Kirkup, Siyu Guan, Piers Ingram, Konrad Paszkiewicz, Vicente Sancenon, Dipti Thakkar, Zhihao Wu