Patents Assigned to Humn Genome Sciences, Inc.
  • Interferon stimulating protein and uses thereof
    Patent number: 6001806
    Abstract: This invention relates to the use of the baculovirus glycoprotein, Interferon Stimulating Protein (ISP) (also known as gp67, gp64 EFP, or gp64), or the gene sequence encoding ISP, to stimulate production of interferon, such as for immunotherapy, anti-viral, anti-cancer, anti-bacterial, or anti-parasitic therapy. This invention also relates to novel mutant forms of ISP that show enhanced biological (i.e., anti-viral) activity, increased stability, higher yield or better solubility.
    Type: Grant
    Filed: June 26, 1998
    Date of Patent: December 14, 1999
    Assignees: Humn Genome Sciences, Inc., Washington University
    Inventors: David M. Hilbert, Daniel P. Bednarik, Bernadetta Nardelli, Marianne Murphy, David Parmelee, Ann Gronowski, Robert Schreiber