Abstract: The present invention discloses a flexible connecting structure of a prefabricated component and a building main body. The flexible connecting structure comprises multiple layers of cast-in-situ building main bodies spaced up and down, a prefabricated component is connected between two adjacent cast-in-situ building main bodies, a tenon is provided at the lower end of the prefabricated component, a mortise matching the tenon is provided on the top surface of the cast-in-situ building main body, and the prefabricated component is socketed to the lower layer of cast-in-situ building main body by tenon-and-mortise cooperation; and a first flexible layer for reducing the connection rigidity between the prefabricated component and the upper layer of cast-in-situ building main body is provided at the junction between the prefabricated component and the upper layer of cast-in-situ building main body.