Patents Assigned to HUNAN NORMAL UNIVERSITY
  • Patent number: 11857644
    Abstract: A multi-signal fluorescent probe, represented by: A method for preparing the multi-signal fluorescent probe includes: (a) adding 2-methoxyphenothiazine and ethyl iodide into a mixture of dichloromethane (DCM) and acetonitrile followed by a first reaction and a first post-treatment to obtain 10-ethyl-2-methoxy-10H-phenothiazine; (b) adding boron tribromide into the 10-ethyl-2-methoxy-10H-phenothiazine under an inert gas followed by a second reaction under an ice bath and a second post-treatment to obtain 10-ethyl-10H-phenothiazin-2-ol; and (c) mixing the 10-ethyl-10H-phenothiazin-2-ol, malonic acid, zinc chloride and phosphorus oxychloride followed by a third reaction and a third post-treatment to obtain the multi-signal fluorescent probe. A use of the multi-signal fluorescent probe in the detection of intracellular ONOO? and Na2S2 is also provided.
    Type: Grant
    Filed: March 24, 2023
    Date of Patent: January 2, 2024
    Assignees: Hunan Cancer Hospital, Hunan Normal University
    Inventors: Huijun Zhou, Zhenyang Liu, Pan Chen, Xiaming Zhang, Peng Yin, Ting Li
  • Patent number: 11192011
    Abstract: The present disclosure relates to a physical training apparatus, and in particular to a relay race training apparatus. The relay race training apparatus includes a tread mill, a column disposed at a side of the tread mill through a linear driving device, a swinging device disposed on the column, and a catching and releasing device connected to the swinging device, wherein the swinging device is used to simulate swinging and turning over of the catching and releasing device by a baton passer or a baton receiver in a running process, the catching and releasing device includes a catching and releasing body, a holding groove for holding a baton is disposed on the catching and releasing body, a limiting plate for limiting the position of the baton and a driving mechanism for driving the limiting plate to move along the baton are disposed in the holding groove.
    Type: Grant
    Filed: May 29, 2021
    Date of Patent: December 7, 2021
    Assignee: HUNAN NORMAL UNIVERSITY
    Inventor: Tao Gong