Abstract: This invention relates to a method of inhibiting the expression of TNF? or IL-1? with a compound of the following formula: wherein R1 and R2 are defined herein. It also relates to is a method of treating inflammatory bowel disease with such a compound.
Type:
Grant
Filed:
March 11, 2005
Date of Patent:
December 1, 2009
Assignee:
Hutchison MediPharma Enterprises Ltd.
Inventors:
Xiaoqiang Yan, Tao Wang, Zhiming Ma, Ke Pan, Weihan Zhang, Jianrong Hong, Jeff Duan, Yu Cai