Abstract: Genes can be introduced into plants that confer desirable traits such as, drought and stress tolerance, insect and pest resistance, as well as environmental qualities such as phyto-remediation. However, possibility for transgene escape to wild and non-transformed species raises commercial and ecological concerns. Disclosed herein are methods and compositions for generating sterile plants for the prevention of transgene escape.
Type:
Grant
Filed:
February 7, 2003
Date of Patent:
April 28, 2009
Assignees:
HybriGene, Inc., Rutgers, The State University of New Jersey
Inventors:
Hong Luo, Qian Hu, Kimberly Nelson Vasilchik, John P. Longo, Albert P. Kausch, Barbara Zilinskas, Subha Lakkaraju
Abstract: A method for detecting interactions between first and second interacting molecules at variable sensitivity. This variable sensitivity may be obtained by providing for the overexpression of either a bait hybrid protein containing a DNA binding domain (desensitization) or a prey hybrid protein containing the DNA activation domain for a reporter gene (enhanced sensitivity). The use of exogenous activators of one or the other according to the needs of a particular system is readily accomplished.
Type:
Grant
Filed:
October 6, 2000
Date of Patent:
September 14, 2004
Assignee:
Hybrigen, Inc.
Inventors:
David N. Edwards, Arlene Leon, David F. Ranney
Abstract: Genes can be introduced into plants that confer desirable traits such as, drought and stress tolerance, insect and pest resistance, as well as environmental qualities such as phyto-remediation. However, possibility for transgene escape to wild and non-transformed species raises commercial and ecological concerns. Disclosed herein are methods and compositions for generating sterile plants for the prevention of transgene escape.
Type:
Application
Filed:
February 7, 2003
Publication date:
October 2, 2003
Applicant:
HybriGene, Inc.
Inventors:
Hong Luo, Qian Hu, Kimberly Nelson Vasilchik, John P. Longo, Albert P. Kausch