Abstract: The present invention concerns combinations of inecalcitol with an anti-CD38 agent such as daratumumab, MOR 202 or isatuximab for the treatment of cancer, such as hematological malignancies by increasing or inducing the expression of CD-38 by inecalcitol.
Type:
Grant
Filed:
July 20, 2017
Date of Patent:
November 19, 2019
Assignee:
HYBRIGENICS S.A.
Inventors:
Susan Benjamin, Cécile Planquette, Rémi Delansorne
Abstract: The present invention concerns collections of recombinant cell clones derived from a prokaryotic genome, more particularly from Helicobacter pylori genome, useable for two-hybrid systems and methods to produce such collections. The invention further relates to then identification of H. pylori protein-protein interactions and to the application of said collections of recombinant cell clones and said identified proteins interactions to the pharmaceutical and diagnostic field.
Type:
Grant
Filed:
October 30, 2001
Date of Patent:
July 12, 2005
Assignee:
Hybrigenics S.A.
Inventors:
Pierre Legrain, Luc Selig, Jean-Christophe Rain