Abstract: The present invention is concerned with a method and a kit for detecting an interaction between a first membrane bound test protein or fragment thereof and a second test protein or fragment thereof which is either membrane bound or soluble with an in vivo genetic system based in yeast, bacterial or mammalian cells. The system makes use of the reconstitution of the split ubiquitin protein.
Type:
Grant
Filed:
March 28, 2003
Date of Patent:
September 6, 2016
Assignee:
Hybrigenics Services S.A.S.
Inventors:
Igor Stagljar, Michael Hottiger, Daniel Auerbach