Patents Assigned to Hyde Park West, LLC
  • METHOD AND DEVICE FOR IDENTIFICATION OF ONE CARBON PATHWAY GENE VARIANTS AS STROKE RISK MARKERS, COMBINED DATA MINING, LOGISTIC REGRESSION, AND PATHWAY ANALYSIS
    Publication number: 20140142060
    Abstract: The disclosure provides method and device using a whole genome association analysis toolset for a total stroke case, versus a control group, which demonstrated significant associations with p less than 1.00E.03 for 5 genes, including polymorphisms in MTHFR, MTRR, and BHMT. These gene polymorphisms in MTHFR may remove or create intron and exon splice enhancer sites that affect alternative splicing activity as well as appropriate mRNA and protein production.
    Type: Application
    Filed: November 19, 2013
    Publication date: May 22, 2014
    Applicant: Hyde Park West, LLC
    Inventors: Stuart A. Stein, Reed M. Stein