Patents Assigned to Hyperfine Research, Inc.
  • Publication number: 20180143275
    Abstract: Some aspects include a method of detecting change in biological subject matter of a patient positioned within a low-field magnetic resonance imaging device, the method comprising: while the patient remains positioned within the low-field magnetic resonance device: acquiring first magnetic resonance image data of a portion of the patient; acquiring second magnetic resonance image data of the portion of the patient subsequent to acquiring the first magnetic resonance image data; aligning the first magnetic resonance image data and the second magnetic resonance image data; and comparing the aligned first magnetic resonance image data and second magnetic resonance image data to detect at least one change in the biological subject matter of the portion of the patient.
    Type: Application
    Filed: November 21, 2017
    Publication date: May 24, 2018
    Applicant: Hyperfine Research, Inc.
    Inventors: Michal Sofka, Jonathan M. Rothberg, Gregory L. Charvat, Tyler S. Ralston
  • Publication number: 20180143274
    Abstract: According to some aspects, a low-field magnetic resonance imaging system is provided. The low-field magnetic resonance imaging system comprises a magnetics system having a plurality of magnetics components configured to produce magnetic fields for performing magnetic resonance imaging, the magnetics system comprising, a B0 magnet configured to produce a B0 field for the magnetic resonance imaging system at a low-field strength of less than 0.
    Type: Application
    Filed: November 22, 2017
    Publication date: May 24, 2018
    Applicant: Hyperfine Research, Inc.
    Inventors: Michael Stephen Poole, Cedric Hugon, Hadrien A. Dyvorne, Laura Sacolick, William J. Mileski, Jeremy Christopher Jordan, Alan B. Katze, JR., Jonathan M. Rothberg, Todd Rearick, Christopher Thomas McNulty
  • Publication number: 20180144467
    Abstract: Some aspects include a method of determining change in size of an abnormality in a brain of a patient positioned within a low-field magnetic resonance imaging (MRI) device. The method comprises, while the patient remains positioned within the low-field MRI device, acquiring first and second magnetic resonance (MR) image data of the patient's brain; providing the first and second MR image data as input to a trained statistical classifier to obtain corresponding first and second output; identifying, using the first output, at least one initial value of at least one feature indicative of a size of the abnormality; identifying, using the second output, at least one updated value of the at least one feature; determining the change in the size of the abnormality using the at least one initial value of the at least one feature and the at least one updated value of the at least one feature.
    Type: Application
    Filed: November 21, 2017
    Publication date: May 24, 2018
    Applicant: Hyperfine Research, Inc.
    Inventors: Michal Sofka, Jonathan M. Rothberg, Gregory L. Charvat, Tyler S. Ralston
  • Publication number: 20180143281
    Abstract: Some aspects include a method of detecting change in degree of midline shift in a brain of a patient. The method comprises, while the patient remains positioned within the low-field magnetic resonance imaging device, acquiring first magnetic resonance (MR) image data and second MR image data of the patient's brain; providing the first and second MR data as input to a trained statistical classifier to obtain corresponding first and second output, identifying, from the first output, at least one initial location of at least one landmark associated with at least one midline structure of the patient's brain; identifying, from the second output, at least one updated location of the at least one landmark; and determining a degree of change in the midline shift using the at least one initial location of the at least one landmark and the at least one updated location of the at least one landmark.
    Type: Application
    Filed: November 21, 2017
    Publication date: May 24, 2018
    Applicant: Hyperfine Research, Inc.
    Inventors: Michal Sofka, Jonathan M. Rothberg, Gregory L. Charvat, Tyler S. Ralston
  • Publication number: 20180088193
    Abstract: Some aspects comprise a tuning system configured to tune a radio frequency coil for use with a magnetic resonance imaging system comprising a tuning circuit including at least one tuning element configured to affect a frequency at which the radio frequency coil resonates, and a controller configured to set at least one value for the tuning element to cause the radio frequency coil to resonate at approximately a Larmor frequency of the magnetic resonance imaging system determined by the tuning system. Some aspects include a method of automatically tuning a radio frequency coil comprising determining information indicative of a Larmor frequency of the magnetic resonance imaging system, using a controller to automatically set at least one value of a tuning circuit to cause the radio frequency coil to resonate at approximately the Larmor frequency based on the determined information.
    Type: Application
    Filed: September 29, 2017
    Publication date: March 29, 2018
    Applicant: Hyperfine Research, Inc.
    Inventors: Todd Rearick, Jeremy Christopher Jordan, Gregory L. Charvat, Matthew Scot Rosen
  • Publication number: 20180038931
    Abstract: According to some aspects, a method of suppressing noise in an environment of a magnetic resonance imaging system is provided. The method comprising estimating a transfer function based on multiple calibration measurements obtained from the environment by at least one primary coil and at least one auxiliary sensor, respectively, estimating noise present in a magnetic resonance signal received by the at least one primary coil based at least in part on the transfer function, and suppressing noise in the magnetic resonance signal using the noise estimate.
    Type: Application
    Filed: September 29, 2017
    Publication date: February 8, 2018
    Applicant: Hyperfine Research, Inc.
    Inventors: Todd Rearick, Gregory L. Charvat, Matthew Scot Rosen, Jonathan M. Rothberg
  • Publication number: 20180024208
    Abstract: According to some aspects, a laminate panel is provided. The laminate panel comprises at least one laminate layer including at least one non-conductive layer and at least one conductive layer patterned to form at least a portion of a B0 coil configured to contribute to a B0 field suitable for use in low-field magnetic resonance imaging (MRI).
    Type: Application
    Filed: September 29, 2017
    Publication date: January 25, 2018
    Applicant: Hyperfine Research, Inc.
    Inventors: Jonathan M. Rothberg, Matthew Scot Rosen, Gregory L. Charvat, William J. Mileski, Todd Rearick, Michael Stephen Poole, Keith G. Fife
  • Patent number: 9817093
    Abstract: According to some aspects, a laminate panel is provided. The laminate panel comprises at least one laminate layer including at least one non-conductive layer and at least one conductive layer patterned to form at least a portion of a B0 coil configured to contribute to a B0 field suitable for use in low-field magnetic resonance imaging (MRI).
    Type: Grant
    Filed: September 4, 2015
    Date of Patent: November 14, 2017
    Assignee: Hyperfine Research, Inc.
    Inventors: Jonathan M. Rothberg, Matthew Scot Rosen, Gregory L. Charvat, William J. Mileski, Todd Rearick, Michael Stephen Poole, Keith G. Fife
  • Patent number: 9797971
    Abstract: According to some aspects, a method of suppressing noise in an environment of a magnetic resonance imaging system is provided. The method comprising estimating a transfer function based on multiple calibration measurements obtained from the environment by at least one primary coil and at least one auxiliary sensor, respectively, estimating noise present in a magnetic resonance signal received by the at least one primary coil based at least in part on the transfer function, and suppressing noise in the magnetic resonance signal using the noise estimate.
    Type: Grant
    Filed: December 21, 2016
    Date of Patent: October 24, 2017
    Assignee: Hyperfine Research, Inc.
    Inventors: Todd Rearick, Gregory L. Charvat, Matthew Scot Rosen, Jonathan M. Rothberg
  • Publication number: 20170276749
    Abstract: According to some aspects, a method of producing a permanent magnet shim configured to improve a profile of a B0 magnetic field produced by a B0 magnet is provided. The method comprises determining deviation of the B0 magnetic field from a desired B0 magnetic field, determining a magnetic pattern that, when applied to magnetic material, produces a corrective magnetic field that corrects for at least some of the determined deviation, and applying the magnetic pattern to the magnetic material to produce the permanent magnet shim. According to some aspects, a permanent magnet shim for improving a profile of a B0 magnetic field produced by a B0 magnet is provided. The permanent magnet shim comprises magnetic material having a predetermined magnetic pattern applied thereto that produces a corrective magnetic field to improve the profile of the B0 magnetic field.
    Type: Application
    Filed: March 22, 2017
    Publication date: September 28, 2017
    Applicant: Hyperfine Research, Inc.
    Inventors: Cedric Hugon, Michael Stephen Poole, Tyler S. Ralston
  • Publication number: 20170276747
    Abstract: According to some aspects, a method of producing a permanent magnet shim configured to improve a profile of a B0 magnetic field produced by a B0 magnet is provided. The method comprises determining deviation of the B0 magnetic field from a desired B0 magnetic field, determining a magnetic pattern that, when applied to magnetic material, produces a corrective magnetic field that corrects for at least some of the determined deviation, and applying the magnetic pattern to the magnetic material to produce the permanent magnet shim. According to some aspects, a permanent magnet shim for improving a profile of a B0 magnetic field produced by a B0 magnet is provided. The permanent magnet shim comprises magnetic material having a predetermined magnetic pattern applied thereto that produces a corrective magnetic field to improve the profile of the B0 magnetic field.
    Type: Application
    Filed: March 23, 2017
    Publication date: September 28, 2017
    Applicant: Hyperfine Research, Inc.
    Inventors: Cedric Hugon, Michael Stephen Poole, Tyler S. Ralston
  • Patent number: 9645210
    Abstract: A thermal management component adapted to cool, when present, at least one component of a magnetic resonance imaging (MRI) system is described. The thermal management component is adapted to reduce or eliminate eddy current production during operation of the MRI system. The thermal management component comprises at least one conduit configured to circulate coolant, and at least one thermally-conductive substrate coupled to the at least one conduit and configured to transfer heat from the at least one component to the coolant when circulated through the at least one conduit, wherein the at least one thermally-conductive substrate is configured to reduce or eliminate eddy current production.
    Type: Grant
    Filed: September 4, 2015
    Date of Patent: May 9, 2017
    Assignee: Hyperfine Research, Inc.
    Inventors: Christopher Thomas McNulty, Michael Stephen Poole, Gregory L. Charvat, Matthew Scot Rosen, Jonathan M. Rothberg
  • Patent number: 9638773
    Abstract: In some aspects, a magnetic system for use in a low-field MRI system. The magnetic system comprises at least one electromagnet configured to, when operated, generate a magnetic field to contribute to a B0 field for the low-field MRI system, and at least one permanent magnet to produce a magnetic field to contribute to the B0 field.
    Type: Grant
    Filed: September 4, 2015
    Date of Patent: May 2, 2017
    Assignee: Hyperfine Research, Inc.
    Inventors: Michael Stephen Poole, Todd Rearick, Jonathan M. Rothberg
  • Patent number: 9625544
    Abstract: In some aspects, a magnetic system for use in a low-field MRI system. The magnetic system comprises at least one electromagnet configured to, when operated, generate a magnetic field to contribute to a B0 field for the low-field MRI system, and at least one permanent magnet to produce a magnetic field to contribute to the B0 field.
    Type: Grant
    Filed: April 6, 2016
    Date of Patent: April 18, 2017
    Assignee: Hyperfine Research, Inc.
    Inventors: Michael Stephen Poole, Todd Rearick, Jonathan M. Rothberg
  • Patent number: 9625543
    Abstract: According to some aspects, a method of suppressing noise in an environment of a magnetic resonance imaging system is provided. The method comprising estimating a transfer function based on multiple calibration measurements obtained from the environment by at least one primary coil and at least one auxiliary sensor, respectively, estimating noise present in a magnetic resonance signal received by the at least one primary coil based at least in part on the transfer function, and suppressing noise in the magnetic resonance signal using the noise estimate.
    Type: Grant
    Filed: February 22, 2016
    Date of Patent: April 18, 2017
    Assignee: Hyperfine Research, Inc.
    Inventors: Todd Rearick, Gregory L. Charvat, Matthew Scot Rosen, Jonathan M. Rothberg
  • Publication number: 20170102443
    Abstract: According to some aspects, a method of suppressing noise in an environment of a magnetic resonance imaging system is provided. The method comprising estimating a transfer function based on multiple calibration measurements obtained from the environment by at least one primary coil and at least one auxiliary sensor, respectively, estimating noise present in a magnetic resonance signal received by the at least one primary coil based at least in part on the transfer function, and suppressing noise in the magnetic resonance signal using the noise estimate.
    Type: Application
    Filed: December 21, 2016
    Publication date: April 13, 2017
    Applicant: Hyperfine Research, Inc.
    Inventors: Todd Rearick, Gregory L. Charvat, Matthew Scot Rosen, Jonathan M. Rothberg
  • Patent number: 9547057
    Abstract: According to some aspects, a method of suppressing noise in an environment of a magnetic resonance imaging system is provided. The method comprising estimating a transfer function based on multiple calibration measurements obtained from the environment by at least one primary coil and at least one auxiliary sensor, respectively, estimating noise present in a magnetic resonance signal received by the at least one primary coil based at least in part on the transfer function, and suppressing noise in the magnetic resonance signal using the noise estimate.
    Type: Grant
    Filed: September 4, 2015
    Date of Patent: January 17, 2017
    Assignee: Hyperfine Research, Inc.
    Inventors: Todd Rearick, Gregory L. Charvat, Matthew Scot Rosen, Jonathan M. Rothberg
  • Patent number: 9541616
    Abstract: According to some aspects, a laminate panel is provided. The laminate panel comprises at least one laminate layer including at least one non-conductive layer and at least one conductive layer patterned to form at least a portion of a B0 coil configured to contribute to a B0 field suitable for use in low-field magnetic resonance imaging (MRI).
    Type: Grant
    Filed: February 22, 2016
    Date of Patent: January 10, 2017
    Assignee: Hyperfine Research, Inc.
    Inventors: Jonathan M. Rothberg, Matthew Scot Rosen, Gregory L. Charvat, William J. Mileski, Todd Rearick, Michael Stephen Poole
  • Publication number: 20160334479
    Abstract: Aspects relate to providing radio frequency components responsive to magnetic resonance signals. According to some aspects, a radio frequency component comprises at least one coil having a conductor arranged in a plurality of turns oriented about a region of interest to respond to corresponding magnetic resonant signal components. According to some aspects, the radio frequency component comprises a plurality of coils oriented to respond to corresponding magnetic resonant signal components. According to some aspects, an optimization is used to determine a configuration for at least one radio frequency coil.
    Type: Application
    Filed: May 12, 2016
    Publication date: November 17, 2016
    Applicant: Hyperfine Research, Inc.
    Inventors: Michael Stephen Poole, Gregory L. Charvat, Todd Rearick, Jonathan M. Rothberg
  • Publication number: 20160299203
    Abstract: An apparatus to provide power for operating at least one gradient coil of a magnetic resonance imaging system. According to some aspects, the apparatus comprises a plurality of power terminals configured to supply different voltages of a first polarity, and a linear amplifier configured to provide at least one output to power the at least one gradient coil to produce a magnetic field in accordance with a pulse sequence, the linear amplifier configured to be powered by one or more of the plurality of power terminals, wherein the one or more of the plurality of power terminals powering the linear amplifier is selected based, at least in part, on the at least one output.
    Type: Application
    Filed: April 13, 2016
    Publication date: October 13, 2016
    Applicant: Hyperfine Research, Inc.
    Inventors: William J. Mileski, Gregory L. Charvat, Jonathan M. Rothberg, Jeremy Christopher Jordan