Patents Assigned to Hypermed Imaging, Inc.
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Patent number: 10010278Abstract: The disclosure provides methods and systems for determining tissue oxygenation. An electronic device obtains a data set including a plurality of images of a tissue of interest, each resolved at a different spectral band. Spectral analysis is performed, upon image registration, at a plurality of points in a two-dimensional area of the images of the tissue. The spectral analysis including determining approximate values of oxyhemoglobin levels and deoxyhemoglobin levels at each respective point in the plurality of points. The predetermined set of eight to twelve spectral bands includes spectral bands that provide improved methods for measuring tissue oxygenation.Type: GrantFiled: September 15, 2016Date of Patent: July 3, 2018Assignee: Hypermed Imaging, Inc.Inventors: Mark Anthony Darty, Dmitry Yudovsky
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Patent number: 9795303Abstract: Apparatus and methods for hyperspectral imaging analysis that assists in real and near-real time assessment of biological tissue condition, viability, and type, and monitoring the above overtime. Embodiments of the invention are particularly useful in surgery, clinical procedures, tissue assessment, diagnostic procedures, health monitoring, and medical evaluations, especially in the detection and treatment of cancer.Type: GrantFiled: December 7, 2015Date of Patent: October 24, 2017Assignee: Hypermed Imaging, Inc.Inventors: Svetlana V. Panasyuk, Jenny Freeman, Alexander Panasyuk
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Patent number: 9770173Abstract: The invention is directed to a hyperspectral/multispectral system referred to as the OxyVu-1 system. The hyperspectral imaging technology performs spectral analysis at each point in a two-dimensional scanned area producing an image displaying information derived from the analysis. For the OxyVu-1 system, the spectral analytical methods determined in superficial tissues approximate values of oxygen saturation (HT-Sat), oxyhemoglobin levels (HT-Oxy), and deoxyhemoglobin levels (HT-Deoxy). The OxyVu-1 system displays the tissue oxygenation in a two-dimensional, color-coded image. The system contains a system console, a cart, system electronics, CPU, monitor, keyboard, pointing device and printer. The hyperspectral instrument head with support arm contains broadband illuminator, camera and spectral filter for collecting hyperspectral imaging cube. The single use OxyVu Check Pads and Targets are used to perform an instrument check prior to patient measurements.Type: GrantFiled: January 24, 2014Date of Patent: September 26, 2017Assignee: Hypermed Imaging, Inc.Inventors: Svetlana Panasyuk, Jenny Freeman, Kevin Schomacker, Richard Lifsitz
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Patent number: 9766382Abstract: The present disclosure generally relates to hyperspectral spectroscopy, and in particular, to systems, methods and devices enabling a single-sensor hyperspectral imaging device. Hyperspectral (also known as “multispectral”) spectroscopy is an imaging technique that integrates multiples images of an object resolved at different narrow spectral bands (i.e., narrow ranges of wavelengths) into a single data structure, referred to as a three-dimensional hyperspectral data cube. Data provided by hyperspectral spectroscopy allow for the identification of individual components of a complex composition through the recognition of spectral signatures of individual components within the three-dimensional hyperspectral data cube.Type: GrantFiled: March 15, 2013Date of Patent: September 19, 2017Assignee: Hypermed Imaging, Inc.Inventor: Mark Anthony Darty
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Patent number: 9746377Abstract: Provided are methods and systems for concurrent imaging at multiple wavelengths. In one aspect, a hyperspectral/multispectral imaging device includes a lens configured to receive light backscattered by an object, a plurality of photo-sensors, a plurality of bandpass filters covering respective photo-sensors, where each bandpass filter is configured to allow a different respective spectral band to pass through the filter, and a plurality of beam splitters in optical communication with the lens and the photo-sensors, where each beam splitter splits the light received by the lens into a plurality of optical paths, each path configured to direct light to a corresponding photo-sensor through the bandpass filter corresponding to the respective photo-sensor.Type: GrantFiled: November 15, 2016Date of Patent: August 29, 2017Assignee: Hypermed Imaging, Inc.Inventors: Mark Anthony Darty, Michael Tilleman, Peter Meenen, Dmitry Yudovsky
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Patent number: 9655519Abstract: An imaging system collects a plurality of images of an extremity of a subject, each collected at a unique spectral band. A physiologic arterial parameter of the extremity is determined from the plurality of images upon image registration. A record of the physiological arterial parameter is recorded in an electronic data store and an indication of the parameter is outputted. The method is performed by a medical professional associated with a temporal clinical expenditure cost in an epoch, for an entity. The product of the (i) epoch and the (ii) temporal clinical expenditure cost is less than a difference between (a) an average or absolute reimbursement associated with the current procedural terminology code by the entity and (b) incidental expenditures associated with the performance of the method.Type: GrantFiled: March 20, 2015Date of Patent: May 23, 2017Assignee: Hypermed Imaging, Inc.Inventors: Mark Anthony Darty, Dmitry Yudovsky
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Patent number: 9648254Abstract: Provided are methods and systems for concurrent imaging at multiple wavelengths. In one aspect, a hyperspectral/multispectral imaging device includes a lens configured to receive light backscattered by an object, a plurality of photo-sensors, a plurality of bandpass filters covering respective photo-sensors, where each bandpass filter is configured to allow a different respective spectral band to pass through the filter, and a plurality of beam splitters in optical communication with the lens and the photo-sensors, where each beam splitter splits the light received by the lens into a plurality of optical paths, each path configured to direct light to a corresponding photo-sensor through the bandpass filter corresponding to the respective photo-sensor.Type: GrantFiled: March 20, 2015Date of Patent: May 9, 2017Assignee: Hypermed Imaging, Inc.Inventors: Mark Anthony Darty, Michael Tilleman, Peter Meenen, Dmitry Yudovsky
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Patent number: 9619883Abstract: The disclosure provides computer systems, non-transitory computer-readable storage medium, and methods for determining the presence of a skin indication in a subject. In some aspects the method includes acquiring a hyperspectral imaging data set from a region of interest of a human subject using a hyperspectral imager, and applying the hyperspectral imaging data set against a classifier including a two layered media model, the two layered media model including a first layer of a modeled human tissue overlying a second layer of the modeled human tissue, where the two layered media model has been trained by application of simulated data across a set of optical and geometric properties associated with the presence or the absence of a skin indication, where the two layered media model computes tissue reflectance R from the modeled human tissue by a relationship provided herein.Type: GrantFiled: March 17, 2014Date of Patent: April 11, 2017Assignee: Hypermed Imaging, Inc.Inventor: Dmitry Yudovsky
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Patent number: 9526427Abstract: Provided are methods and systems for concurrent imaging at multiple wavelengths. In one aspect, an imaging device includes at least one objective lens configured to receive light backscattered by an object, a plurality of pixel array photo-sensors, a plurality of bandpass filters covering respective photo-sensors, where each bandpass filter is configured to allow a different respective spectral band to pass through the filter, and a beam steering assembly in optical communication with the at least one objective lens and the photo-sensors. The beam steering assembly directs light received by at least one objective lens from the tissue of a subject to at least one pixel array photo-sensor in the plurality of pixel array photo-sensors.Type: GrantFiled: May 10, 2016Date of Patent: December 27, 2016Assignee: Hypermed Imaging, Inc.Inventors: Mark Anthony Darty, Michael Tilleman, Peter Meenen, Dmitry Yudovsky
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Patent number: 9480424Abstract: The disclosure provides methods and systems for determining tissue oxygenation. An electronic device obtains a data set including a plurality of images of a tissue of interest, each resolved at a different spectral band. Spectral analysis is performed, upon image registration, at a plurality of points in a two-dimensional area of the images of the tissue. The spectral analysis including determining approximate values of oxyhemoglobin levels and deoxyhemoglobin levels at each respective point in the plurality of points. The predetermined set of eight to twelve spectral bands includes spectral bands that provide improved methods for measuring tissue oxygenation.Type: GrantFiled: March 20, 2015Date of Patent: November 1, 2016Assignee: Hypermed Imaging, Inc.Inventors: Mark Anthony Darty, Dmitry Yudovsky
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Patent number: 9354115Abstract: A hyperspectral/multispectral imager comprising a housing is provided. At least one light source is attached to the housing. An objective lens, in an optical communication path comprising originating and terminating ends, is further attached to the housing and causes light to (i) be backscattered by the tissue of a subject at the originating end and then (ii) pass through the objective lens to a beam steering element at the terminating end of the communication path inside the housing. The beam steering element has a plurality of operating modes each of which causes the element to be in optical communication with a different optical detector in a plurality of optical detectors offset from the optical communication path. Each respective detector filter in a plurality of detector filters covers a corresponding optical detector in the plurality of optical detectors thereby filtering light received by the corresponding detector from the beam steering element.Type: GrantFiled: July 16, 2014Date of Patent: May 31, 2016Assignee: Hypermed Imaging, Inc.Inventor: Mark Anthony Darty
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Patent number: 9345428Abstract: The invention is directed to methods and systems of hyperspectral and multispectral imaging of medical tissues. In particular, the invention is directed to new devices, tools and processes for the detection and evaluation of diseases and disorders such as, but not limited to diabetes and peripheral vascular disease and cancer, that incorporate hyperspectral or multispectral imaging.Type: GrantFiled: November 15, 2012Date of Patent: May 24, 2016Assignee: Hypermed Imaging, Inc.Inventors: Jenny Freeman, Svetlana Panasyuk, Michael Hopmeier, Kevin Schomacker, Derek Brand
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Patent number: 9326715Abstract: The invention is directed to a hyperspectral/multispectral system referred to as the OxyVu-1 system. The hyperspectral imaging technology performs spectral analysis at each point in a two-dimensional scanned a producing an image displaying information derived from the analysis. For the OxyVu-1 system, the spectral analytical methods determined in superficial tissues approximate values of oxygen saturation (HT-Sat), oxyhemoglobin levels (HT-oxy), and deoxyhemoglobin levels (HT-deoxy). The OxyVu-1 system displays the tissue oxygenation in a two-dimensional, color-coded image. The system contains a system console, a cart, system electronics, CPU, monitor, keyboard, pointing device and printer. The hyperspectral instrument head with support arm contains broadband illuminator, camera and spectral filter for collecting hyperspectral imaging cube. The single use OxyVu Check Pads and Targets are used to perform an instrument check prior to patient measurements.Type: GrantFiled: December 26, 2012Date of Patent: May 3, 2016Assignee: Hypermed Imaging, Inc.Inventors: Svetlana Panasyuk, Jenny Freeman, Kevin Schomacker, Richard Lifsitz
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Patent number: 9204805Abstract: Apparatus and methods for hyperspectral imaging analysis that assists in real and near-real time assessment of biological tissue condition, viability, and type, and monitoring the above over time. Embodiments of the invention are particularly useful in surgery, clinical procedures, tissue assessment, diagnostic procedures, health monitoring, and medical evaluations, especially in the detection and treatment of cancer.Type: GrantFiled: November 15, 2012Date of Patent: December 8, 2015Assignee: Hypermed Imaging, Inc.Inventors: Svetlana Panasyuk, Jenny Freeman, Alexander Panasyuk
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Patent number: 9107624Abstract: A hyperspectral/multispectral imager comprising a housing is provided. At least one light source is attached to the housing. An objective lens, in an optical communication path comprising originating and terminating ends, is further attached to the housing and causes light to (i) be backscattered by the tissue of a subject at the originating end and then (ii) pass through the objective lens to a beam steering element at the terminating end of the communication path inside the housing. The beam steering element has a plurality of operating modes each of which causes the element to be in optical communication with a different optical detector in a plurality of optical detectors offset from the optical communication path. Each respective detector filter in a plurality of detector filters covers a corresponding optical detector in the plurality of optical detectors thereby filtering light received by the corresponding detector from the beam steering element.Type: GrantFiled: March 15, 2013Date of Patent: August 18, 2015Assignee: Hypermed Imaging, Inc.Inventor: Mark Anthony Darty
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Patent number: 9084533Abstract: A medical instrument that comprises: a first-stage optic responsive to a tissue surface of a patient; a spectral separator optically responsive to the first stage optic and having a control input; an imaging sensor optically responsive to the spectral separator and having an image data output; and a diagnostic processor having an image acquisition interface with an input responsive to the imaging sensor and a filter control interface having a control output provided to the control input of the spectral separator.Type: GrantFiled: April 29, 2013Date of Patent: July 21, 2015Assignee: Hypermed Imaging, Inc.Inventors: Jenny E. Freeman, Edgar N. Lewis
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Patent number: 9078619Abstract: The present invention provides a hyperspectral imaging system which demonstrates changes in tissue oxygen delivery, extraction and saturation during shock and resuscitation including an imaging apparatus for performing real-time or near real-time assessment and monitoring of shock, including hemorrhagic, hypovolemic, cardiogenic, neurogenic, septic or burn shock. The information provided by the hyperspectral measurement can deliver physiologic measurements that support early detection of shock and also provide information about likely outcomes.Type: GrantFiled: December 28, 2005Date of Patent: July 14, 2015Assignee: Hypermed Imaging, Inc.Inventors: Svetlana V. Panasyuk, Jenny E. Freeman, Michael J. Hopmeier, Alexander A. Panasyuk, Brian H. Tracey
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Publication number: 20150177429Abstract: The present disclosure generally relates to hyperspectral spectroscopy, and in particular, to systems, methods and devices enabling a single-sensor hyperspectral imaging device. Hyperspectral (also known as “multispectral”) spectroscopy is an imaging technique that integrates multiples images of an object resolved at different narrow spectral bands (i.e., narrow ranges of wavelengths) into a single data structure, referred to as a three-dimensional hyperspectral data cube. Data provided by hyperspectral spectroscopy allow for the identification of individual components of a complex composition through the recognition of spectral signatures of individual components within the three-dimensional hyperspectral data cube.Type: ApplicationFiled: March 15, 2013Publication date: June 25, 2015Applicant: HYPERMED IMAGING, INC.Inventor: Mark Anthony DARTY
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Patent number: 8971984Abstract: This invention relates generally to an index map comprising both pressure and perfusion information from a diabetic patient foot for the purpose of treatment. The index map may also be a map of perfusion and/or metabolism of the tissue (reflecting oxygen delivery and oxygen extraction), obtained by thermal imaging, hyperspectral imaging, or duplex ultrasound, MRA, CT or laser Doppler imaging. This information aids treatment in prevention of diabetic foot ulceration and amputation and in treatment of tissue compromise to prevent tissue loss in other body regions.Type: GrantFiled: August 21, 2006Date of Patent: March 3, 2015Assignee: Hypermed Imaging, Inc.Inventors: Jenny E. Freeman, Svetlana V. Panasyuk, Michael J. Hopmeier, Derek Brand, Kevin Schomacker
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Patent number: D758468Type: GrantFiled: December 10, 2014Date of Patent: June 7, 2016Assignee: Hypermed Imaging, Inc.Inventors: Mark Anthony Darty, Michael Paloian, Anthony Orchard