Abstract: The use of a cytochrome P-450 enzyme comprising SEQ ID NO: 110, or a variant enzyme having at least 70% identity thereto and having CYP-450 activity, for the hydroxylation of an organic compound, wherein the amino acid residue at position 291 is not threonine.
Type:
Grant
Filed:
May 14, 2019
Date of Patent:
April 4, 2023
Assignee:
HYPHA DISCOVERY LTD.
Inventors:
Jonathan Charles Paul Steele, Antonio De Riso, Francesco Falcioni, Richard Kerry Phipps, Stephen Keith Wrigley, Kinga Linda Nytko, Vincent Poon, Sebastian Schulz, John Maxim Ward, Mariacristina Bawn
Abstract: The use of a cytochrome P-450 enzyme comprising SEQ ID NO: 110, or a variant enzyme having at least 70% identity thereto and having CYP-450 activity, for the hydroxylation of an organic compound, wherein the amino acid residue at position 291 is not threonine.
Type:
Application
Filed:
May 14, 2019
Publication date:
July 29, 2021
Applicant:
HYPHA DISCOVERY LTD.
Inventors:
Jonathan Charles Paul STEELE, Antonio DE RISO, Francesco FALCIONI, Richard Kerry PHIPPS, Stephen Keith WRIGLEY, Kinga Linda NYTKO, Vincent POON, Sebastian SCHULZ, John Maxim WARD, Mariacristina BAWN