Patents Assigned to Hypnion, Inc.
  • Benzisoxazole piperidine compounds and methods of use thereof
    Patent number: 8129410
    Abstract: The invention includes benzisoxazole piperidine compositions and methods of using them for modulating sleep.
    Type: Grant
    Filed: April 26, 2006
    Date of Patent: March 6, 2012
    Assignee: Hypnion, Inc.
    Inventors: Daniel Coughlin, James F. White, Kazumi Shiosaki, David G. Hangauer, Michael Solomon, Dale M. Edgar
  • Loxapine analogs and methods of use thereof
    Patent number: 8101596
    Abstract: The invention relates to novel compounds and methods of using them for modulating sleep.
    Type: Grant
    Filed: March 25, 2009
    Date of Patent: January 24, 2012
    Assignee: Hypnion Inc.
    Inventors: Dale M. Edgar, David G. Hangauer, Michael Solomon
  • Benzisoxazole piperazine compounds and methods of use thereof
    Patent number: 8088778
    Abstract: The invention includes benzisoxazole piperazine compositions and methods of using them for modulating sleep.
    Type: Grant
    Filed: February 11, 2009
    Date of Patent: January 3, 2012
    Assignee: Hypnion, Inc.
    Inventors: Daniel Coughlin, James F. White, Kazumi Shiosaki, David G. Hangauer, Michael Solomon, Dale M. Edgar
  • Olanzapine analogs and methods of use thereof
    Patent number: 7807828
    Abstract: The invention relates to novel compounds and methods of using them for modulating sleep.
    Type: Grant
    Filed: August 10, 2006
    Date of Patent: October 5, 2010
    Assignee: Hypnion, Inc.
    Inventors: Michael Solomon, Dale Edgar, David Hangauer, Kazumi Shiosaki, James White
  • Loxapine analogs and methods of use thereof
    Patent number: 7592333
    Abstract: The invention relates to novel compounds and methods of using them for modulating sleep.
    Type: Grant
    Filed: September 21, 2005
    Date of Patent: September 22, 2009
    Assignee: Hypnion, Inc.
    Inventors: Dale M. Edgar, David G. Hangauer, Kazumi Shiosaki, Michael Solomon, James F. White
  • Quetiapine analogs and methods of use thereof
    Patent number: 7563785
    Abstract: The invention relates to novel compounds and methods of using them for modulating sleep.
    Type: Grant
    Filed: September 21, 2005
    Date of Patent: July 21, 2009
    Assignee: Hypnion, Inc.
    Inventors: Dale Edgar, David Hangauer, Kazumi Shiosaki, Michael Solomon, James White
  • Methods of treating sleep disorders
    Patent number: 7524864
    Abstract: The invention relates to novel antihistamines and methods of modulating sleep by administering a doxepin analog or a pharmaceutically effective salt thereof.
    Type: Grant
    Filed: April 25, 2005
    Date of Patent: April 28, 2009
    Assignee: Hypnion, Inc.
    Inventors: Dale M. Edgar, David G. Hangauer, James F. White
  • Benzisoxazole piperazine compounds and methods of use thereof
    Patent number: 7494998
    Abstract: The invention includes benzisoxazole piperazine compositions and methods of using them for modulating sleep.
    Type: Grant
    Filed: April 26, 2006
    Date of Patent: February 24, 2009
    Assignee: Hypnion, Inc.
    Inventors: Daniel Coughlin, James F. White, Kazumi Shiosaki, David G. Hangauer, Michael Solomon, Dale M. Edgar
  • Doxepin analogs and methods of use thereof
    Patent number: 7482460
    Abstract: The invention relates to novel doxepin analog compounds and methods of modulating sleep by administering such compounds, or a pharmaceutically effective salt thereof.
    Type: Grant
    Filed: April 25, 2005
    Date of Patent: January 27, 2009
    Assignee: Hypnion, Inc.
    Inventors: Dale M. Edgar, David G. Hangauer, James F. White, Michael Solomon
  • Doxepin analogs and methods of use thereof
    Patent number: 7411069
    Abstract: The invention relates to novel antihistamines and methods of modulating sleep by administering a doxepin analog or a pharmaceutically effective salt thereof.
    Type: Grant
    Filed: April 23, 2004
    Date of Patent: August 12, 2008
    Assignee: Hypnion, Inc.
    Inventors: Dale M. Edgar, David G. Hangauer, James F. White, Michael Solomon
  • Treatment of CNS disorders using CNS target modulators
    Patent number: 7355042
    Abstract: The invention is directed to compositions and methods useful for treating Central Nervous System (CNS) disorders. Furthermore, the invention provides compositions and methods of treating sleep disorders. More specifically, the invention is directed to the compositions and use of derivatized, histamine antagonists for the treatment of sleep disorders.
    Type: Grant
    Filed: April 23, 2004
    Date of Patent: April 8, 2008
    Assignee: Hypnion, Inc.
    Inventors: Dale M. Edgar, David G. Hangauer, Harry Jefferson Leighton, Emmanuel J. M. Mignot, James F. White, Michael Solomon, Kazumi Shiosaki
  • Doxepin analogs and methods of use thereof
    Patent number: 7326721
    Abstract: The invention relates to novel doxepin analog compounds and methods of modulating sleep by administering such compounds, or a pharmaceutically effective salt thereof.
    Type: Grant
    Filed: December 10, 2004
    Date of Patent: February 5, 2008
    Assignee: Hypnion, Inc.
    Inventors: Dale M. Edgar, David G. Hangauer, James F. White, Michael Solomon
  • CNS target modulators
    Patent number: 7317026
    Abstract: The invention is directed to compositions used for treating Central Nervous System (CNS) disorders. More specifically, the invention is directed to derivatized, e.g., ester or carboxylic acid derivatized, doxepins, and analogs thereof, useful for the treatment of sleep disorders.
    Type: Grant
    Filed: December 4, 2003
    Date of Patent: January 8, 2008
    Assignee: Hypnion, Inc.
    Inventors: Dale M. Edgar, David G. Hangauer, Harry Jefferson Leighton, Emmanuel J. M. Mignot
  • Treatment of sleep disorders using CNS target modulators
    Patent number: 7189757
    Abstract: The invention is directed to compositions used for treating Central Nervous System (CNS) disorders. In addition, the invention provides convenient methods of treatment of a CNS disorder. Furthermore, the invention provides methods of treating sleep disorders using compositions that remain active for a discrete period of time to reduce side effects. More specifically, the invention is directed to the compositions and use of derivatized, e.g., ester or carboxylic acid derivatized, antihistamine antagonists for the treatment of sleep disorders.
    Type: Grant
    Filed: October 16, 2002
    Date of Patent: March 13, 2007
    Assignee: Hypnion, Inc.
    Inventors: Dale M. Edgar, David G. Hangauer, Harry Jefferson Leighton, Emmanuel J. M. Mignot
  • CNS target modulators
    Publication number: 20040142972
    Abstract: The invention is directed to compositions used for treating Central Nervous System (CNS) disorders. In addition, the invention provides convenient methods of treatment of a CNS disorder. Furthermore, the invention provides methods of treating sleep disorders using compositions that remain active for a discrete period of time to reduce side effects. More specifically, the invention is directed to the compositions and use of derivatized, e.g., ester or carboxylic acid derivatized, antihistamine antagonists for the treatment of sleep disorders.
    Type: Application
    Filed: December 4, 2003
    Publication date: July 22, 2004
    Applicant: Hypnion, Inc.
    Inventors: Dale M. Edgar, David G. Hangauer, Harry Jefferson Leighton, Emmanuel J.M. Mignot
  • Treatment of sleeping disorders using CNS sleep target modulators
    Publication number: 20030232839
    Abstract: The invention is directed to compositions used for treating sleep disorders. In addition, the invention provides convenient methods of treatment of a sleep disorder. Furthermore, the invention provides methods of treating sleep disorders using compositions that remain active for a discrete period of time to reduce side effects. More specifically, the invention is directed to the compositions and use of ester derivatized trazodone compounds for the treatment of sleep disorders.
    Type: Application
    Filed: January 21, 2003
    Publication date: December 18, 2003
    Applicant: Hypnion, Inc.
    Inventors: David G. Hangauer, Harry Jefferson Leighton, Dale M. Edgar
  • Treatment of CNS disorders using CNS target modulators
    Publication number: 20030187021
    Abstract: The invention is directed to compositions used for treating Central Nervous System (CNS) disorders. In addition, the invention provides convenient methods of treatment of a CNS disorder. Furthermore, the invention provides methods of treating sleep disorders using compositions that remain active for a discrete period of time to reduce side effects. More specifically, the invention is directed to the compositions and use of derivatized, e.g., ester or carboxylic acid derivatized, antihistamine antagonists for the treatment of sleep disorders.
    Type: Application
    Filed: October 16, 2002
    Publication date: October 2, 2003
    Applicant: Hypnion, Inc.
    Inventors: Dale M. Edgar, David G. Hangauer, Harry Jefferson Leighton, Emmanuel J.M. Mignot