Patents Assigned to HYSENSBIO
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Publication number: 20240190916Abstract: A novel peptide, a polynucleotide encoding the peptide, an expression vector including the polynucleotide, and a pharmaceutical composition, quasi-drug composition, or health functional food composition including the peptide are disclosed. Uses of the peptide, polynucleotide, expression vector, and compositions are also disclosed.Type: ApplicationFiled: March 24, 2023Publication date: June 13, 2024Applicant: HYSENSBIOInventors: Joo Hwang PARK, Dong Seol Lee, Ji Hyun Lee
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Patent number: 11905337Abstract: Provided are a novel peptide, a polynucleotide encoding the peptide, an expression vector including the polynucleotide, and a pharmaceutical composition including the peptide, a quasi-drug composition including the peptide, and a health functional food composition including the peptide.Type: GrantFiled: May 5, 2022Date of Patent: February 20, 2024Assignee: HYSENSBIOInventors: Joo Hwang Park, Ji Hyun Lee
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Publication number: 20230310278Abstract: A drug mixing unit for a syringe is disclosed. The drug mixing unit contains a barrel member having a first flow path through which a liquid drug is to be pushed in; and a plug member having an insertion part inserted into the barrel member, the insertion part having a second flow path, for drawing out a drug mixture, formed on inner side thereof and a through hole, connected to the second flow path, formed on one surface thereof, wherein the plug member is connected to the barrel member to form a predetermined drug mixing space, the drug mixing space has a drug to be mixed with the liquid drug that has been pushed in through the first flow path. The unit also contain a third flow path, through which the drug mixture flows from the drug mixing space to the through hole.Type: ApplicationFiled: September 3, 2021Publication date: October 5, 2023Applicant: HYSENSBIOInventors: Joo Hwang PARK, Dong Seol LEE
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Publication number: 20230257419Abstract: The present invention provides a pharmaceutical composition for preventing or treating periodontal disease or a dislocated traumatic tooth, comprising a peptide of a specific amino acid sequence and a composition for regenerating periodontium.Type: ApplicationFiled: June 1, 2021Publication date: August 17, 2023Applicant: HYSENSBIO CO., LTD.Inventors: Joo Hwang PARK, Ji Hyun LEE, Dong Seol LEE
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Patent number: 11612555Abstract: An oral care composition for alleviating dentin hyperesthesia is disclosed. The oral care composition includes a peptide consisting of an amino acid sequence of the following Formula 1: K—Y-R1-R2-R3-R4-R5-R6-R7-R8??(Formula 1) wherein R1 is arginine (R), lysine (K) or glutamine (Q); R2 is arginine (R) or glutamine (Q); R3, R4, and R5 are arginine (R) or lysine (K), respectively; R6 is asparagine (N) or serine(S); and R7 and R8 are lysine (K) or tyrosine (Y), respectively.Type: GrantFiled: April 17, 2019Date of Patent: March 28, 2023Assignee: HYSENSBIOInventors: Joo Hwang Park, Ji Hyun Lee
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Patent number: 11452682Abstract: A toothpaste composition for alleviating dentin hyperesthesia is disclosed. The composition includes a peptide consisting of an amino acid sequence of the following Formula 1: K-Y-R1-R2-R3-R4-R5-R6-R7-R8??(Formula 1) wherein R1 is arginine (R), lysine (K) or glutamine (Q); R2 is arginine (R) or glutamine (Q); R3, R4, and R5 are arginine (R) or lysine (K), respectively; R6 is asparagine (N) or serine (S); and R7 and R8 are lysine (K) or tyrosine (Y), respectively.Type: GrantFiled: April 17, 2019Date of Patent: September 27, 2022Assignee: HYSENSBIOInventors: Joo Hwang Park, Ji Hyun Lee
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Publication number: 20220267375Abstract: Provided are a novel peptide, a polynucleotide encoding the peptide, an expression vector including the polynucleotide, and a pharmaceutical composition including the peptide, a quasi-drug composition including the peptide, and a health functional food composition including the peptide.Type: ApplicationFiled: May 5, 2022Publication date: August 25, 2022Applicant: HYSENSBIOInventors: Joo Hwang PARK, Ji Hyun LEE
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Patent number: 11390648Abstract: A novel peptide and a composition including the peptide are disclosed. The composition may be a pharmaceutical composition, a quasi-drug composition, a dietary supplement, or a food composition. A polynucleotide encoding the peptide and an expression vector including the polynucleotide are also disclosed. The peptide promotes regeneration of hard tissue and is useful for treating dentin-dental pulp diseases or periodontal diseases.Type: GrantFiled: December 17, 2018Date of Patent: July 19, 2022Assignee: HYSENSBIOInventors: Joo Hwang Park, Ji Hyun Lee
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Patent number: 11376310Abstract: Provided are compositions including a CPNE4 protein or a polynucleotide encoding thereof, a pharmaceutical composition, a quasi-drug composition, a dietary supplement, and a health functional food composition. A method for preventing or treating dentin-dental disease or periodontal disease and a method and a method for promoting regeneration of hard tissue including dentin, bone and cementum, and/or pulp tissue are disclosed.Type: GrantFiled: December 17, 2018Date of Patent: July 5, 2022Assignees: HYSENSBIO, SEOUL NATIONAL UNIVERSITY R&DB FOUNDATIONInventors: Joo Hwang Park, Ji Hyun Lee, Joo Cheol Park, Dong Seol Lee
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Publication number: 20220154278Abstract: CPNE7 protein or a nucleotide encoding for CPNE7 protein, or compositions containing the CPNE7 or the nucleotide and their uses are disclosed. The protein, nucleotide, or composition is useful for preventing or treating fatty liver disease. The CPEN7 protein regulates the expression of the SREBF1 (SREBP1) gene or a gene encoding the same. The composition can be a pharmaceutical composition or a quasi-drug composition, a health functional food, or a dietary supplement, which is suitable for preventing or alleviating fatty liver disease.Type: ApplicationFiled: November 16, 2021Publication date: May 19, 2022Applicants: HYSENSBIO, SEOUL NATIONAL UNIVERSITY R&DB FOUNDATIONInventors: Joo Cheol PARK, Dong Seol LEE, Geumbit HWANG
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Publication number: 20210369584Abstract: A toothpaste composition for alleviating dentin hyperesthesia is disclosed. The composition includes a peptide consisting of an amino acid sequence of the following Formula 1: K-Y-R1-R2-R3-R4-R5-R6-R7-R8??(Formula 1) wherein R1 is arginine (R), lysine (K) or glutamine (Q); R2 is arginine (R) or glutamine (Q); R3, R4, and R5 are arginine (R) or lysine (K), respectively; R6 is asparagine (N) or serine (S); and R7 and R8 are lysine (K) or tyrosine (Y), respectively.Type: ApplicationFiled: April 17, 2019Publication date: December 2, 2021Applicant: HYSENSBIOInventors: Joo Hwang PARK, Ji Hyun LEE
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Publication number: 20210154123Abstract: An oral care composition for alleviating dentin hyperesthesia is disclosed. The oral care composition includes a peptide consisting of an amino acid sequence of the following Formula 1: K-Y-R1-R2-R3-R4-R5-R6-R7-R8??(Formula 1) wherein R1 is arginine (R), lysine (K) or glutamine (Q); R2 is arginine (R) or glutamine (Q); R3, R4, and R5 are arginine (R) or lysine (K), respectively; R6 is asparagine (N) or serine(S); and R7 and R8 are lysine (K) or tyrosine (Y), respectively.Type: ApplicationFiled: April 17, 2019Publication date: May 27, 2021Applicant: HYSENSBIOInventors: Joo Hwang PARK, Ji Hyun LEE
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Publication number: 20210061855Abstract: A novel peptide and a composition including the peptide are disclosed. The composition may be a pharmaceutical composition, a quasi-drug composition, a dietary supplement, or a food composition. A polynucleotide encoding the peptide and an expression vector including the polynucleotide are also disclosed. The peptide promotes regeneration of hard tissue and is useful for treating dentin-dental pulp diseases or periodontal diseases.Type: ApplicationFiled: December 17, 2018Publication date: March 4, 2021Applicant: HYSENSBIOInventors: Joo Hwang PARK, Ji-Hyun LEE
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Publication number: 20210052699Abstract: Provided are compositions including a CPNE4 protein or a polynucleotide encoding thereof, a pharmaceutical composition, a quasi-drug composition, a dietary supplement, and a health functional food composition. A method for preventing or treating dentin-dental disease or periodontal disease and a method and a method for promoting regeneration of hard tissue including dentin, bone and cementum, and/or pulp tissue are disclosed.Type: ApplicationFiled: December 17, 2018Publication date: February 25, 2021Applicants: HYSENSBIO, SEOUL NATIONAL UNIVERSITY R&DB FOUNDATIONInventors: Joo Hwang PARK, Ji Hyun LEE, Joo Cheol PARK, Dong Seol LEE
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Patent number: 10844092Abstract: Provided are a novel peptide, a polynucleotide encoding the peptide, an expression vector including the polynucleotide, and a pharmaceutical composition including the peptide, a quasi-drug composition including the peptide, and a health functional food composition including the peptide.Type: GrantFiled: January 28, 2019Date of Patent: November 24, 2020Assignee: HysensBio Co., Ltd.Inventors: Joohwang Park, Jihyun Lee
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Patent number: 10428110Abstract: Provided are a novel peptide, a polynucleotide encoding the peptide, an expression vector including the polynucleotide, and a pharmaceutical composition including the peptide, a quasi-drug composition including the peptide, and a health functional food composition including the peptide.Type: GrantFiled: December 12, 2017Date of Patent: October 1, 2019Assignee: HysensBio Co., Ltd.Inventors: Joohwang Park, Jihyun Lee
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Publication number: 20190153033Abstract: Provided are a novel peptide, a polynucleotide encoding the peptide, an expression vector including the polynucleotide, and a pharmaceutical composition including the peptide, a quasi-drug composition including the peptide, and a health functional food composition including the peptide.Type: ApplicationFiled: January 28, 2019Publication date: May 23, 2019Applicant: HysensBio Co., Ltd.Inventors: Joohwang PARK, Jihyun LEE
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Publication number: 20180179254Abstract: Provided are a novel peptide, a polynucleotide encoding the peptide, an expression vector including the polynucleotide, and a pharmaceutical composition including the peptide, a quasi-drug composition including the peptide, and a health functional food composition including the peptide.Type: ApplicationFiled: December 12, 2017Publication date: June 28, 2018Applicant: HysensBio Co., Ltd.Inventors: Joohwang PARK, Jihyun LEE