Patents Assigned to HYSENSBIO
  • Publication number: 20240190916
    Abstract: A novel peptide, a polynucleotide encoding the peptide, an expression vector including the polynucleotide, and a pharmaceutical composition, quasi-drug composition, or health functional food composition including the peptide are disclosed. Uses of the peptide, polynucleotide, expression vector, and compositions are also disclosed.
    Type: Application
    Filed: March 24, 2023
    Publication date: June 13, 2024
    Applicant: HYSENSBIO
    Inventors: Joo Hwang PARK, Dong Seol Lee, Ji Hyun Lee
  • Patent number: 11905337
    Abstract: Provided are a novel peptide, a polynucleotide encoding the peptide, an expression vector including the polynucleotide, and a pharmaceutical composition including the peptide, a quasi-drug composition including the peptide, and a health functional food composition including the peptide.
    Type: Grant
    Filed: May 5, 2022
    Date of Patent: February 20, 2024
    Assignee: HYSENSBIO
    Inventors: Joo Hwang Park, Ji Hyun Lee
  • Publication number: 20230310278
    Abstract: A drug mixing unit for a syringe is disclosed. The drug mixing unit contains a barrel member having a first flow path through which a liquid drug is to be pushed in; and a plug member having an insertion part inserted into the barrel member, the insertion part having a second flow path, for drawing out a drug mixture, formed on inner side thereof and a through hole, connected to the second flow path, formed on one surface thereof, wherein the plug member is connected to the barrel member to form a predetermined drug mixing space, the drug mixing space has a drug to be mixed with the liquid drug that has been pushed in through the first flow path. The unit also contain a third flow path, through which the drug mixture flows from the drug mixing space to the through hole.
    Type: Application
    Filed: September 3, 2021
    Publication date: October 5, 2023
    Applicant: HYSENSBIO
    Inventors: Joo Hwang PARK, Dong Seol LEE
  • Publication number: 20230257419
    Abstract: The present invention provides a pharmaceutical composition for preventing or treating periodontal disease or a dislocated traumatic tooth, comprising a peptide of a specific amino acid sequence and a composition for regenerating periodontium.
    Type: Application
    Filed: June 1, 2021
    Publication date: August 17, 2023
    Applicant: HYSENSBIO CO., LTD.
    Inventors: Joo Hwang PARK, Ji Hyun LEE, Dong Seol LEE
  • Patent number: 11612555
    Abstract: An oral care composition for alleviating dentin hyperesthesia is disclosed. The oral care composition includes a peptide consisting of an amino acid sequence of the following Formula 1: K—Y-R1-R2-R3-R4-R5-R6-R7-R8??(Formula 1) wherein R1 is arginine (R), lysine (K) or glutamine (Q); R2 is arginine (R) or glutamine (Q); R3, R4, and R5 are arginine (R) or lysine (K), respectively; R6 is asparagine (N) or serine(S); and R7 and R8 are lysine (K) or tyrosine (Y), respectively.
    Type: Grant
    Filed: April 17, 2019
    Date of Patent: March 28, 2023
    Assignee: HYSENSBIO
    Inventors: Joo Hwang Park, Ji Hyun Lee
  • Patent number: 11452682
    Abstract: A toothpaste composition for alleviating dentin hyperesthesia is disclosed. The composition includes a peptide consisting of an amino acid sequence of the following Formula 1: K-Y-R1-R2-R3-R4-R5-R6-R7-R8??(Formula 1) wherein R1 is arginine (R), lysine (K) or glutamine (Q); R2 is arginine (R) or glutamine (Q); R3, R4, and R5 are arginine (R) or lysine (K), respectively; R6 is asparagine (N) or serine (S); and R7 and R8 are lysine (K) or tyrosine (Y), respectively.
    Type: Grant
    Filed: April 17, 2019
    Date of Patent: September 27, 2022
    Assignee: HYSENSBIO
    Inventors: Joo Hwang Park, Ji Hyun Lee
  • Publication number: 20220267375
    Abstract: Provided are a novel peptide, a polynucleotide encoding the peptide, an expression vector including the polynucleotide, and a pharmaceutical composition including the peptide, a quasi-drug composition including the peptide, and a health functional food composition including the peptide.
    Type: Application
    Filed: May 5, 2022
    Publication date: August 25, 2022
    Applicant: HYSENSBIO
    Inventors: Joo Hwang PARK, Ji Hyun LEE
  • Patent number: 11390648
    Abstract: A novel peptide and a composition including the peptide are disclosed. The composition may be a pharmaceutical composition, a quasi-drug composition, a dietary supplement, or a food composition. A polynucleotide encoding the peptide and an expression vector including the polynucleotide are also disclosed. The peptide promotes regeneration of hard tissue and is useful for treating dentin-dental pulp diseases or periodontal diseases.
    Type: Grant
    Filed: December 17, 2018
    Date of Patent: July 19, 2022
    Assignee: HYSENSBIO
    Inventors: Joo Hwang Park, Ji Hyun Lee
  • Patent number: 11376310
    Abstract: Provided are compositions including a CPNE4 protein or a polynucleotide encoding thereof, a pharmaceutical composition, a quasi-drug composition, a dietary supplement, and a health functional food composition. A method for preventing or treating dentin-dental disease or periodontal disease and a method and a method for promoting regeneration of hard tissue including dentin, bone and cementum, and/or pulp tissue are disclosed.
    Type: Grant
    Filed: December 17, 2018
    Date of Patent: July 5, 2022
    Assignees: HYSENSBIO, SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION
    Inventors: Joo Hwang Park, Ji Hyun Lee, Joo Cheol Park, Dong Seol Lee
  • Publication number: 20220154278
    Abstract: CPNE7 protein or a nucleotide encoding for CPNE7 protein, or compositions containing the CPNE7 or the nucleotide and their uses are disclosed. The protein, nucleotide, or composition is useful for preventing or treating fatty liver disease. The CPEN7 protein regulates the expression of the SREBF1 (SREBP1) gene or a gene encoding the same. The composition can be a pharmaceutical composition or a quasi-drug composition, a health functional food, or a dietary supplement, which is suitable for preventing or alleviating fatty liver disease.
    Type: Application
    Filed: November 16, 2021
    Publication date: May 19, 2022
    Applicants: HYSENSBIO, SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION
    Inventors: Joo Cheol PARK, Dong Seol LEE, Geumbit HWANG
  • Publication number: 20210369584
    Abstract: A toothpaste composition for alleviating dentin hyperesthesia is disclosed. The composition includes a peptide consisting of an amino acid sequence of the following Formula 1: K-Y-R1-R2-R3-R4-R5-R6-R7-R8??(Formula 1) wherein R1 is arginine (R), lysine (K) or glutamine (Q); R2 is arginine (R) or glutamine (Q); R3, R4, and R5 are arginine (R) or lysine (K), respectively; R6 is asparagine (N) or serine (S); and R7 and R8 are lysine (K) or tyrosine (Y), respectively.
    Type: Application
    Filed: April 17, 2019
    Publication date: December 2, 2021
    Applicant: HYSENSBIO
    Inventors: Joo Hwang PARK, Ji Hyun LEE
  • Publication number: 20210154123
    Abstract: An oral care composition for alleviating dentin hyperesthesia is disclosed. The oral care composition includes a peptide consisting of an amino acid sequence of the following Formula 1: K-Y-R1-R2-R3-R4-R5-R6-R7-R8??(Formula 1) wherein R1 is arginine (R), lysine (K) or glutamine (Q); R2 is arginine (R) or glutamine (Q); R3, R4, and R5 are arginine (R) or lysine (K), respectively; R6 is asparagine (N) or serine(S); and R7 and R8 are lysine (K) or tyrosine (Y), respectively.
    Type: Application
    Filed: April 17, 2019
    Publication date: May 27, 2021
    Applicant: HYSENSBIO
    Inventors: Joo Hwang PARK, Ji Hyun LEE
  • Publication number: 20210061855
    Abstract: A novel peptide and a composition including the peptide are disclosed. The composition may be a pharmaceutical composition, a quasi-drug composition, a dietary supplement, or a food composition. A polynucleotide encoding the peptide and an expression vector including the polynucleotide are also disclosed. The peptide promotes regeneration of hard tissue and is useful for treating dentin-dental pulp diseases or periodontal diseases.
    Type: Application
    Filed: December 17, 2018
    Publication date: March 4, 2021
    Applicant: HYSENSBIO
    Inventors: Joo Hwang PARK, Ji-Hyun LEE
  • Publication number: 20210052699
    Abstract: Provided are compositions including a CPNE4 protein or a polynucleotide encoding thereof, a pharmaceutical composition, a quasi-drug composition, a dietary supplement, and a health functional food composition. A method for preventing or treating dentin-dental disease or periodontal disease and a method and a method for promoting regeneration of hard tissue including dentin, bone and cementum, and/or pulp tissue are disclosed.
    Type: Application
    Filed: December 17, 2018
    Publication date: February 25, 2021
    Applicants: HYSENSBIO, SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION
    Inventors: Joo Hwang PARK, Ji Hyun LEE, Joo Cheol PARK, Dong Seol LEE
  • Patent number: 10844092
    Abstract: Provided are a novel peptide, a polynucleotide encoding the peptide, an expression vector including the polynucleotide, and a pharmaceutical composition including the peptide, a quasi-drug composition including the peptide, and a health functional food composition including the peptide.
    Type: Grant
    Filed: January 28, 2019
    Date of Patent: November 24, 2020
    Assignee: HysensBio Co., Ltd.
    Inventors: Joohwang Park, Jihyun Lee
  • Patent number: 10428110
    Abstract: Provided are a novel peptide, a polynucleotide encoding the peptide, an expression vector including the polynucleotide, and a pharmaceutical composition including the peptide, a quasi-drug composition including the peptide, and a health functional food composition including the peptide.
    Type: Grant
    Filed: December 12, 2017
    Date of Patent: October 1, 2019
    Assignee: HysensBio Co., Ltd.
    Inventors: Joohwang Park, Jihyun Lee
  • Publication number: 20190153033
    Abstract: Provided are a novel peptide, a polynucleotide encoding the peptide, an expression vector including the polynucleotide, and a pharmaceutical composition including the peptide, a quasi-drug composition including the peptide, and a health functional food composition including the peptide.
    Type: Application
    Filed: January 28, 2019
    Publication date: May 23, 2019
    Applicant: HysensBio Co., Ltd.
    Inventors: Joohwang PARK, Jihyun LEE
  • Publication number: 20180179254
    Abstract: Provided are a novel peptide, a polynucleotide encoding the peptide, an expression vector including the polynucleotide, and a pharmaceutical composition including the peptide, a quasi-drug composition including the peptide, and a health functional food composition including the peptide.
    Type: Application
    Filed: December 12, 2017
    Publication date: June 28, 2018
    Applicant: HysensBio Co., Ltd.
    Inventors: Joohwang PARK, Jihyun LEE