Abstract: Provided are anti-GM-CSF antibodies or fragments thereof including humanized antibodies and fragments. Also provided are uses of the antibodies and fragments for therapeutic, diagnostic and prognostic purposes. Therapeutic uses of the antibodies and fragments, for example include the treatment of inflammatory and autoimmune diseases and disorders.
Type:
Grant
Filed:
December 2, 2020
Date of Patent:
March 12, 2024
Assignee:
I-Mab Biopharma (Hangzhou) Co., Ltd.
Inventors:
Zhengyi Wang, Lei Fang, Bingshi Guo, Jingwu Zang
Abstract: The present disclosure provides antibodies that bind Lymphocyte Activation Gene-3 (LAG-3). Also provided are methods of stimulating an immune response, inhibiting growth of tumor cells, and treating an autoimmune, inflammatory, or viral disease.
Type:
Grant
Filed:
November 18, 2019
Date of Patent:
August 16, 2022
Assignee:
I-MAB BIOPHARMA (HANGZHOU) CO., LTD.
Inventors:
Lei Fang, Zhengyi Wang, Bingshi Guo, Jingwu Zang, Wenqing Jiang, Yongqiang Wang