Patents Assigned to I.N.R.A.
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Publication number: 20120270786Abstract: The present invention generally relates to the field of nutrition and health. In particular, the present invention provides a composition that allows it to treat, limit or prevent muscle atrophy. Embodiments of the present invention are directed at GLP-2 containing compositions and to compositions that stimulate the secretion of GLP-2 in a body to treat or prevent muscle atrophy.Type: ApplicationFiled: October 7, 2010Publication date: October 25, 2012Applicants: I.N.R.A., NESTEC S.A.Inventors: Didier Attaix, Audrey Codran-Raison, Irene Corthesy-Theulaz, Denis Breuille, Lydie Combaret
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Patent number: 7992521Abstract: The inventive device for automatically detecting the mating of animals is wearable by an animal. The device includes a fixing to an animal mechanism, a detector for an attempt of mating a female animal by the animal with the fixing mechanism, and an identifier for an electronic label which is introduced in the body of the female animal and actuated by the detector and/or by the female animal identification device by processing the image of at least one part of the female animal triggered by the detector. The identifier includes a communicator with an electronic label carried by a female animal. The communicator can read the electronic label identifier of each female animal which the animal attempts to mate. The communication can also be provided with a device for storing representative information on the attempted mating in the random access memory of the electronic label.Type: GrantFiled: December 20, 2004Date of Patent: August 9, 2011Assignees: Centre International d'Etudes Superieures en Sciences Agronomiques de Montepelliar (Montepellier Supagro), Institut National de la Recherche Agronomique (I.N.R.A.)Inventor: François Bocquier
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Publication number: 20040170952Abstract: The invention relates to nucleic acid molecules which make it possible to detect those genes of the MHC involved in the phenomena of resistance or susceptibility to the development of virus-induced tumours.Type: ApplicationFiled: January 14, 2002Publication date: September 2, 2004Applicants: C.N.R.S., I.N.R.A.Inventors: Rima Zoorob, Charles Auffray, Anne-Marie Chausse
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Patent number: 6162637Abstract: Method for the production of vanillic acid and vanillin by bioconversion from ferulic acid in a medium containing phospholipids cultured with at least one microorganism from the classes Ascomycetes, Basidiomycetes or Actinomycetes. Vanillin is also produced by bioconversion of vanillic acid by at least one microorganism of the class Basidiomycetes in a medium containing cellobiose.Type: GrantFiled: December 18, 1998Date of Patent: December 19, 2000Assignee: Institut National de la Recherche Agronomique - I.N.R.A.Inventors: Laurence Lesage-Meessen, Michel Delattre, Mireille Haon, Marcel Asther
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Patent number: 6087131Abstract: An acid-stable .beta.-glucosidase that may be prepared from filamentous fungi and has very low glucose inhibition sensitivity is disclosed. Said .beta.-glucosidase is particularly useful for preparing fruit juices and in enzymatic cellulose hydrolysis methods.Type: GrantFiled: January 6, 1998Date of Patent: July 11, 2000Assignee: Institut National de la Recherche Agronomique - I.N.R.A.Inventors: Yusuf Ziya Gunata, Marie-Jose Vallier, Raymond Baumes, Claude Bayonove
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Patent number: 5866380Abstract: Method for the production of vanillic acid and vanillin by bioconversion from ferulic acid in a medium containing phospholipids cultured with at least one microorganism from the classes Ascomycetes, Basidiomycetes or Actinomycetes. Vanillin is also produced by bioconversion of vanillic acid by at least one microorganism of the class Basidiomycetes in a medium containing cellobiose.Type: GrantFiled: June 12, 1997Date of Patent: February 2, 1999Assignee: Institut National De La Recherche Agronomique-I.N.R.A.Inventors: Laurence Lesage-Meessen, Michel Delattre, Mireille Haon, Marcel Asther
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Patent number: 5712152Abstract: Yeast strains containing at least one copy of gene encoding a lactic bacteria lacticodeshydrogenase, under the control of sequences regulating the expression of said gene in the yeast. The invention also encompasses expression vectors for use in producing said yeast strains.Type: GrantFiled: November 25, 1994Date of Patent: January 27, 1998Assignee: Institut National de la Recherche Agronomique - I.N.R.A.Inventors: Sylvie Dequin, Pierre Barre
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Patent number: 5646018Abstract: Nod factors of general formula (I): ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 are hydrogen atom, a carbamyl group or an acetyl group; R.sub.5 is the aliphatic chain of a fatty acid; n is 1-4; and one or more of substituents R.sub.1, R.sub.2 and R.sub.3 is a carbamyl group, and/or R.sub.4 is a methyl group, and/or R.sub.6 is an optionally substituted monosaccharide or oligosaccharide attached to the glucosamin via a glycoside bond.Type: GrantFiled: February 1, 1995Date of Patent: July 8, 1997Assignees: Institut National de la Recherche Agronomique - I.N.R.A., Centre National de la Recherche Scientifique - C.N.R.S.Inventors: William John Broughton, Jean Louis Claude Denarie, Fabienne Chantal Marie Maillet, Neil Philip John Price, Danielle Jean Claudine Prome, Jean-Claude Adrien Paul Prome, Biserka Relic, Franck Jean Bernard Talmont
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Patent number: 5597689Abstract: The subject of the invention is the use of a DNA fragment comprising a sequence from the 3' end of the AcNPV baculovirus IE1 gene, optionally combined with a DNA fragment comprising a sequence situated upstream of the promoter of the IE1 gene, for producing vectors permitting the replication and maintenance of genetic information in animal cells.The invention also encompasses the episomal vectors obtained, as well as the transformed cells comprising the vectors.Type: GrantFiled: July 26, 1994Date of Patent: January 28, 1997Assignees: Institut National de la Recherche Agronomique (I.N.R.A.), Centre National de la Recherche Scientifique (C.N.R.S.)Inventors: G erard Devauchelle, Martine Cerutti, C ecile Persillon
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Patent number: 5587304Abstract: An isolated nucleic acid fragment comprising a sequence of 1620 bp encoding the malolactic enzyme of Lactococcus lactis.Type: GrantFiled: January 17, 1995Date of Patent: December 24, 1996Assignee: Institut National de la Recherche Agronomique - I.N.R.A.Inventors: Pierre Barre, Sylvie Dequin, Virginie Ansanay
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Patent number: 5549718Abstract: An essentially pure substance has a structure of a Nod factor or one of its analogues. The Nod factor is characterized by the fact that its biosynthesis is controlled by at least one nodulation gene (nodA,B,C) common to the Rhizobiaceae, in particular to the genera Rhizobium, Bradyrhizobium, Sinorhizobium and Azorhizobium. This substance consists of a lipo-oligosaccharide which is not a derivative of the exopolysaccharides and which has the general formula (I). In formula (I), the Nod factor of which it has the structure is a plant-specific symbiotic signal and is capable of enhancing the capacity of the bacteria of infect the host plant with which it is associated and/or of accelerating the formation of nodules on the host plant with which it is associated and/or of inducing the transcription of symbiotic genes of the leguminoseae. Applications to the treatment of plants and as an active therapeutic agent in humans and animals.Type: GrantFiled: September 30, 1994Date of Patent: August 27, 1996Assignees: Centre National de la Recherche Scientifique (C.N.R.S.), Institut National de la Recherche Agronomique (I.N.R.A.)Inventors: Patrice Lerouge, Philippe Roche, Catherine Faucher, Fabienne Maillet, Jean Denarie, Jean-Claude Prome, Georges Truchet
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Patent number: 5378823Abstract: Variants of type I interferons containing peptide extensions, and their production using recombinant DNA techniques, are described. Expression cassettes comprising DNA coding for the variant interferon, DNA coding for a signal peptide, and a promoter are described for use in transforming yeast and in the production of the variant interferons.Type: GrantFiled: September 11, 1992Date of Patent: January 3, 1995Assignee: Institut National de la Recherche Agronomique-I.N.R.A.Inventors: Jacques Martal, Erich DeGryse, Pierre Gaye, Madia Charlier, Gilles Charpigny, Pierrette Reinaud, Gerard Chaouat
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Patent number: 4839648Abstract: A method of determining the trajectory of a body (1) such as a vehicle body on a relatively plane path portion (2), the method being characterized in that it consists: in forming a main real image (4) of the path portion in a plane (19) at a non-zero angle (5) with the path portion; in decomposing said main image as formed into a plurality of points (21); in determining the relationship between the size of a unit length (30) taken substantially at the level of the path portion and the size of its image formed in the main image the size being a function of the number of points covered by the image and of the location of the unit length on said path portion; in determining a secondary image (32) in the main image, the secondary image corresponding to a longitudinal reference mark (31) related to the vehicle on the path portion; and in determining the various successive positions (32, 33, 34) of the secondary image by correlation of the number of points covered by the secondary image, given that the secondary imType: GrantFiled: January 14, 1988Date of Patent: June 13, 1989Assignees: Association Pour La Recherche et le Developpement Des Methodes et Processus Industriels (Armines), Institut National De Recherche Sur Les Transports et Leur Securite (I.N.R.E.T.S.)Inventors: Serge Beucher, Jean-Marc Blosseville, Francois Lenoir
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Patent number: 4188466Abstract: A method and system for the automatic determination of the weight of starch or similar substances in various forms of simple or complex substrates. In a system in accordance with the invention, dispersion of starch is effected by ultrasonics and enzymatic hydrolysis is carried out continuously in segmented form. The colorimetric determination of glucose obtained thereby is also effected continuously in segmented form.Type: GrantFiled: July 6, 1977Date of Patent: February 12, 1980Assignee: I.N.R.A.Inventors: Pierre Thivend, Christiane Mercier-Greenwood, Andre Guilbot
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Method for sampling and fixing urinary metabolites on an immobilizing support and apparatus therefor
Patent number: 4159193Abstract: A method for sampling and fixing urinary metabolites on an immobilizing support which is a paper comprising a substance appropriately activated before use. The determination of the or each required metabolite is expressed in relation to the determination of a metabolite where excretion is constant with time. The appropriately activated substance may be an ion exchange resin or silica gel. The method may be used for determining delta-aminolevulinic acid (ALA), or trichloroacetic acid and trichloroethanol conjugated with glucuronic acid, in urine samples.Type: GrantFiled: April 27, 1977Date of Patent: June 26, 1979Assignee: I.N.R.S., Institut National de Recherche et de Securite pour la Prevention des Accidents du travail et des Maladies ProfessionnellesInventors: Philippe Gauntley, Jean-Louis Magadur, Georges Morel